Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody.

Adhesion receptors of the immune system

1990 • 6,585 citations

CD44 is the principal cell surface receptor for hyaluronate

1990 • 2,433 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

1986 • 997 citations

Cell binding function of E-cadherin is regulated by the cytoplasmic domain.

1988 • 811 citations

A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family

1989 • 680 citations

Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition.

1990 • 639 citations

Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis.

1991 • 628 citations

The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells.

1991 • 587 citations

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures.

1990 • 574 citations

A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins

1989 • 568 citations

CD44 — A molecule involved in leukocyte adherence and T-cell activation

1989 • 559 citations

Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion

1991 • 532 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

1991 • 481 citations

Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin.

1989 • 436 citations

A lymphoid cell surface glycoprotein involved in endothelial cell recognition and lymphocyte homing in man

1986 • 435 citations

A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture.

1991 • 399 citations

Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells.

1988 • 382 citations

Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons.

1991 • 377 citations

Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen.

1988 • 374 citations

The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins [published erratum appears in J Cell Biol 1991 Feb;112(3):following 513]

1990 • 368 citations

Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues

1982 • 359 citations

Four molecular pathways of T cell adhesion to endothelial cells: roles of LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions.

1991 • 343 citations

Dual role of the CD44 molecule in T cell adhesion and activation.

1989 • 335 citations

Homing Receptors and Vascular Addressins: Cell Adhesion Molecules that Direct Lymphocyte Traffic

1989 • 332 citations

CD44 contributes to T cell activation.

1989 • 324 citations

Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits.

1989 • 321 citations

Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin

1991 • 294 citations

Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor.

1990 • 285 citations

Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β Subunit

1991 • 262 citations

Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man.

1988 • 257 citations

Aggregation of complement receptors on human neutrophils in the absence of ligand.

1987 • 250 citations

Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.

1990 • 230 citations

On the mode of action of LFA-1

1990 • 208 citations

Binding of hyaluronic acid to lymphoid cell lines is inhibited by monoclonal antibodies against Pgp-1

1990 • 207 citations

Complementation Patterns of Thy-1 Variants and Evidence That Antigen Loss Variants “Pre-Exist” in the Parental Population 2

1974 • 204 citations

Preparation and properties of fluorescein-labelled hyaluronate

1975 • 197 citations

Monoclonal antibodies against the CD44 [In(Lu)-related p80], and Pgp-1 antigens in man recognize the Hermes class of lymphocyte homing receptors.

1989 • 183 citations

Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis.

1990 • 141 citations

Molecular cloning and expression of Pgp-1. The mouse homolog of the human H-CAM (Hermes) lymphocyte homing receptor.

1989 • 133 citations

Isolation and DNA sequence of a cDNA clone encoding a lymphocyte adhesion receptor for high endothelium.

1989 • 132 citations

Structural homology between lymphocyte receptors for high endothelium and class III extracellular matrix receptor.

1989 • 129 citations

Redistribution of a major cell surface glycoprotein during cell movement.

1984 • 115 citations

IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate.

1990 • 115 citations

Expression of transferrin receptor on murine hematopoietic progenitors

1984 • 112 citations

Structural heterogeneity of human Pgp-1 and its relationship with p85

1988 • 97 citations

Identification and characterization of the human Pgp-1 glycoprotein

1986 • 97 citations

Isolation of mouse CD44 cDNA: structural features are distinct from the primate cDNA.

1989 • 94 citations

A role in transmembrane signaling for the cytoplasmic domain of the CD2 T lymphocyte surface antigen

1988 • 93 citations

Identification of mRNA that encodes an alternative form of H-CAM(CD44) in lymphoid and nonlymphoid tissues

1990 • 89 citations

Evidence that the Pgp-1 glycoprotein is expressed on thymus-homing progenitor cells of the thymus

1985 • 88 citations

Genetic characterization of a polymorphic murine cell-surface glycoprotein

1982 • 75 citations

Extracellular calcium results in a conformational change in Mac-1 (CD11b/CD18) on neutrophils. Differentiation of adhesion and phagocytosis functions of Mac-1.

1991 • 70 citations

The cDNA sequence of mouse Pgp-1 and homology to human CD44 cell surface antigen and proteoglycan core/link proteins.

1990 • 67 citations

Evidence for a genetic basis for the class A Thy-1− defect

1980 • 67 citations

Tissue-specific expression of cell-surface Qa-2 antigen from a transfected Q7b gene of C57BL/10 mice.

1987 • 66 citations

Somatic cell mutants distinguish CD44 expression and hyaluronic acid binding

1991 • 62 citations

Characterization of the serum In(Lu)-related antigen: identification of a serum protein related to erythrocyte p80

1989 • 54 citations

Molecules and Regulation in Lymphocyte Migration

1989 • 46 citations

Characterization of autoantibody-secreting B cells in mice undergoing stimulatory (chronic) graft-versus-host reactions. Identification of a CD44hi population that binds specifically to hyaluronate.

1991 • 46 citations

Progenitor cells in the thymus: Most thymus-homing progenitor cells in the adult mouse thymus bear Pgp-1 glycoprotein but not interleukin-2 receptor on their cell surface

1986 • 44 citations

Confirmation by peptide sequence and co-expression on various cell types of the identity of CD44 and P85 glycoprotein

1990 • 41 citations

Dissection of murine lymphocyte-endothelial cell interaction mechanisms by SV-40-transformed mouse endothelial cell lines: Novel mechanisms mediating basal binding, and α4-integrin-dependent cytokine-induced adhesion

1991 • 35 citations