A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules.

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

Two distinct classes of carbohydrate-recognition domains in animal lectins.

1988 • 1,259 citations

Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors

1989 • 1,135 citations

Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro.

1989 • 1,115 citations

GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies.

1989 • 993 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

Cloning of GMP-140, a granule membrane protein of platelets and endothelium: Sequence similarity to proteins involved in cell adhesion and inflammation

1989 • 799 citations

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

1982 • 764 citations

A tissue-specific endothelial cell molecule involved in lymphocyte homing

1988 • 725 citations

Lymphocyte homing into lymph nodes: in vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules.

1976 • 680 citations

Adhesion molecules controlling lymphocyte migration

1989 • 654 citations

Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes.

1988 • 639 citations

Designing CD4 immunoadhesins for AIDS therapy

1989 • 612 citations

PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells

1989 • 538 citations

Cloning of a lymphocyte homing receptor reveals a lectin domain

1989 • 522 citations

Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α

1989 • 495 citations

Mouse Lymph Node Homing Receptor cDNA Clone Encodes a Glycoprotein Revealing Tandem Interaction Domains

1989 • 428 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1.

1989 • 413 citations

Organ specificity of lymphocyte migration: mediation by highly selective lymphocyte interaction with organ‐specific determinants on high endothelial venules

1980 • 347 citations

A Distinct Endothelial Cell Recognition System That Controls Lymphocyte Traffic into Inflamed Synovium

1986 • 317 citations

Isolation and chromosomal localization of cDNAs encoding a novel human lymphocyte cell surface molecule, LAM-1. Homology with the mouse lymphocyte homing receptor and other human adhesion proteins.

1989 • 308 citations

Endothelial-leukocyte adhesion molecule-1-dependent and leukocyte (CD11/CD18)-dependent mechanisms contribute to polymorphonuclear leukocyte adhesion to cytokine-activated human vascular endothelium.

1989 • 288 citations

The Regulation of Lymphocyte Traffic

1986 • 285 citations

T lymphocyte adhesion to endothelial cells: mechanisms demonstrated by anti-LFA-1 monoclonal antibodies.

1986 • 246 citations

Adherence of neutrophils to cultured human microvascular endothelial cells. Stimulation by chemotactic peptides and lipid mediators and dependence upon the Mac-1, LFA-1, p150,95 glycoprotein family.

1989 • 238 citations

Involvement of Sialic Acid on Endothelial Cells in Organ-Specific Lymphocyte Recirculation

1985 • 236 citations

Possible role for cell-surface carbohydrate-binding molecules in lymphocyte recirculation.

1983 • 232 citations

Lymphocyte homing receptors

1986 • 231 citations

Lymphocyte Homing

1989 • 227 citations

Lymphocyte Adherence to High Endothelial Venules: Characterization of a Modified in Vitro Assay, and Examination of the Binding of Syngeneic and Allogeneic Lymphocyte Populations

1979 • 215 citations

Phosphomannosyl receptors may participate in the adhesive interaction between lymphocytes and high endothelial venules.

1984 • 194 citations

Specific Cell-Adhesion Mechanisms Determining Migration Pathways of Recirculating Lymphocytes

1987 • 181 citations

Receptors involved in lymphocyte homing: relationship between a carbohydrate-binding receptor and the MEL-14 antigen.

1987 • 171 citations

Germinal center B cells lack homing receptors necessary for normal lymphocyte recirculation.

1983 • 157 citations

Interferon-gamma regulates an antigen specific for endothelial cells involved in lymphocyte traffic.

1986 • 145 citations

Phosphomannosyl-derivatized beads detect a receptor involved in lymphocyte homing.

1987 • 113 citations

Protection of Mice from Lethal Herpes Simplex Virus Infection by Vaccination with a Secreted form of Cloned Glycoprotein D

1984 • 105 citations

Characterization of a human homologue of the murine peripheral lymph node homing receptor.

1989 • 102 citations

Homing receptors on human and rodent lymphocytes--evidence for a conserved carbohydrate-binding specificity

1987 • 100 citations

Human homologue of mouse lymph node homing receptor: evolutionary conservation at tandem cell interaction domains.

1989 • 99 citations

An in vitro model of lymphocyte homing. II. Membrane and cytoplasmic events involved in lymphocyte adherence to specialized high-endothelial venules of lymph nodes.

1977 • 96 citations

Intravenously injected sialidase inactivates attachment sites for lymphocytes on high endothelial venules.

1989 • 95 citations

Mechanisms of Human Lymphocyte Migration and their Role in the Pathogenesis of Disease

1989 • 95 citations

Demonstration that a lectin-like receptor (gp90MEL) directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes.

1989 • 85 citations

The Mel 14 antibody binds to the lectin domain of the murine peripheral lymph node homing receptor.

1990 • 80 citations

Lymphocyte Adhesion to Psoriatic Dermal Endothelium Is Mediated by a Tissue-specific Receptor/Ligand Interaction

1988 • 74 citations

Rapid decrease in lymphocyte adherence to high endothelial venules in lymph nodes deprived of afferent lymphatic vessels

1987 • 67 citations

Lymphocyte recognition of lymph node high endothelium. VI. Evidence of distinct structures mediating binding to high endothelial cells of lymph nodes and Peyer's patches.

1984 • 65 citations

Prevention of lymphadenopathy in MRL-lpr/lpr mice by blocking peripheral lymph node homing with Mel-14 in vivo.

1988 • 43 citations

Adhesion molecules of cultured hematopoietic malignancies. A calcium-dependent lectin is the principle mediator of binding to the high endothelial venule of lymph nodes.

1989 • 30 citations