Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

The validity of animal models of depression

1984 • 1,365 citations

The dopamine hypothesis of the reinforcing properties of cocaine

1991 • 990 citations

Excitatory amino acid receptors and synaptic plasticity

1990 • 872 citations

Neurotransmitter regulation of dopamine neurons in the ventral tegmental area

1993 • 713 citations

New concepts in cocaine addiction: The dopamine depletion hypothesis

1985 • 608 citations

Stress Down-Regulates Corticosterone Receptors in a Site-Specific Manner in the Brain*

1984 • 586 citations

AMPA glutamate receptor subunits are differentially distributed in rat brain

1993 • 574 citations

Corticosterone levels determine individual vulnerability to amphetamine self-administration.

1991 • 572 citations

Drug addiction: A model for the molecular basis of neural plasticity

1993 • 548 citations

A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function

1991 • 538 citations

Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats

1973 • 523 citations

Postcocaine anhedonia. An animal model of cocaine withdrawal.

1991 • 505 citations

Immunochemical characterization of the non-NMDA glutamate receptor using subunit-specific antibodies. Evidence for a hetero-oligomeric structure in rat brain.

1992 • 505 citations

Persistent sensitization of dopamine neurotransmission in ventral striatum (nucleus accumbens) produced by prior experience with (+)-amphetamine: a microdialysis study in freely moving rats

1988 • 455 citations

Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates

1990 • 442 citations

The role of reward pathways in the development of drug dependence

1987 • 439 citations

Animal models as simulations of depression

1991 • 328 citations

Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area

1992 • 315 citations

Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: electrophysiological and biochemical evidence.

1993 • 308 citations

Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system.

1995 • 291 citations

Non-contingent electric footshock facilitates the acquisition of intravenous cocaine self-administration in rats

1994 • 284 citations

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration.

1989 • 273 citations

Coadministration of MK-801 with amphetamine, cocaine or morphine prevents rather than transiently masks the development of behavioral sensitization

1993 • 242 citations

Depression of Mesolimbic Dopamine Transmission and Sensitization to Morphine During Opiate Abstinence

1992 • 224 citations

Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system

1995 • 222 citations

Morphine and Cocaine Exert Common Chronic Actions on Tyrosine Hydroxylase in Dopaminergic Brain Reward Regions

1991 • 211 citations

MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine

1994 • 203 citations

Cloned Glutamate Receptors

1994 • 176 citations

Regulation of cortical and subcortical glutamate receptor subunit expression by antipsychotic drugs

1995 • 171 citations

DNQX blockade of amphetamine behavioral sensitization

1991 • 163 citations

Selective RNA editing and subunit assembly of native glutamate receptors

1994 • 158 citations

Profound depression of mesolimbic dopamine release after morphine withdrawal in dependent rats

1991 • 155 citations

Development and expression of sensitization to cocaine's reinforcing properties: role of NMDA receptors

1993 • 135 citations

Electrophysiological effects of MK-801 on rat nigrostriatal and mesoaccumbal dopaminergic neurons

1992 • 130 citations

Transmembrane topology of the glutamate receptor subunit GluR6.

1994 • 107 citations

Chronic Cocaine Administration Increases CNS Tyrosine Hydroxylase Enzyme Activity and mRNA Levels and Tryptophan Hydroxylase Enzyme Activity Levels

1993 • 107 citations

Time course of tyrosine hydroxylase expression after behavioral sensitization to cocaine.

1993 • 105 citations

Enhanced stress-induced dopamine release in the prefrontal cortex of amphetamine-sensitized rats

1993 • 100 citations

Long lasting changes in morphine‐induced mesolimbic dopamine release after chronic morphine exposure

1993 • 92 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, And Distinct Properties In The Function Of The Central Nervous System

1989 • 90 citations

Effect of stress on oral morphine and fentanyl self-administration in rats

1992 • 79 citations

Acute withdrawal after repeated ethanol treatment reduces the number of spontaneously active dopaminergic neurons in the ventral tegmental area

1993 • 73 citations

Correlation between behavioral sensitization to cocaine and G protein ADP-ribosylation in the ventral tegmental area

1992 • 72 citations

Sensitization to cocaine and dopamine autoreceptor subsensitivity in the nucleus accumbens

1995 • 68 citations

Effects of ventral striatal 6-OHDA lesions or amphetamine sensitization on ethanol consumption in the rat

1994 • 64 citations

l-Glutamate excitation of A10 dopamine neurons is preferentially mediated by activation of NMDA receptors: extra- and intracellular electrophysiological studies in brain slices

1993 • 58 citations

Amphetamine regulation of mesolimbic dopamine/cholecystokinin neurotransmission

1992 • 55 citations

Molecular Mechanisms of Drug Reinforcement and Addiction

1995 • 32 citations

Chronic Antidepressant Treatment Down-Regulates the Induction of c-fos mRNA in Response to Acute Stress in Rat Frontal Cortex

1995 • 16 citations

NMDA antagonist effects on the development of L-DOPA behavioral sensitization in rats.

1995 • 9 citations