DOCK2 Is Required in T Cell Precursors for Development of Vα14 NK T Cells

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

1994 • 1,044 citations

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

1998 • 951 citations

Lysosomal Glycosphingolipid Recognition by NKT Cells

2004 • 946 citations

CD1 Recognition by Mouse NK1 ⁺ T Lymphocytes

1995 • 903 citations

Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers

2000 • 891 citations

The unconventional lifestyle of NKT cells

2002 • 756 citations

CD1d1 Mutant Mice Are Deficient in Natural T Cells That PromptlyProduce IL-4

1997 • 612 citations

Critical contribution of liver natural killer T cells to a murine model of hepatitis

2000 • 532 citations

A Thymic Precursor to the NK T Cell Lineage

2002 • 517 citations

Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes.

1995 • 517 citations

A Subset of CD4 ⁺ Thymocytes Selected by MHC Class I Molecules

1994 • 464 citations

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

2001 • 443 citations

NKT cells derive from double-positive thymocytes that are positively selected by CD1d

2001 • 421 citations

Augmentation of Vα14 Nkt Cell–Mediated Cytotoxicity by Interleukin 4 in an Autocrine Mechanism Resulting in the Development of Concanavalin a–Induced Hepatitis

2000 • 395 citations

A Natural Killer T (NKT) Cell Developmental Pathway Involving a Thymus-dependent NK1.1−CD4+ CD1d-dependent Precursor Stage

2002 • 374 citations

Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

2005 • 338 citations

Tissue-Specific Segregation of CD1d-Dependent and CD1d-Independent NK T Cells

1999 • 332 citations

Editing of CD1d-Bound Lipid Antigens by Endosomal Lipid Transfer Proteins

2003 • 310 citations

Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice.

1994 • 304 citations

Homeostasis of Vα14i NKT cells

2002 • 291 citations

SAP couples Fyn to SLAM immune receptors

2003 • 282 citations

Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

2003 • 274 citations

An NK1.1+ CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor V beta family.

1992 • 270 citations

Differential dependence of CD4 ⁺ CD25 ⁺ regulatory and natural killer-like T cells on signals leading to NF-κB activation

2004 • 228 citations

Differential Requirements for DOCK2 and Phosphoinositide-3-Kinase γ during T and B Lymphocyte Homing

2004 • 224 citations

SAP Regulates TH2 Differentiation and PKC-θ-Mediated Activation of NF-κB1

2004 • 223 citations

NK1.1+ T Cells in the Liver Arise in the Thymus and Are Selected by Interactions with Class I Molecules on CD4+CD8+ Cells

2000 • 217 citations

The Src Family Tyrosine Kinase Fyn Regulates Natural Killer T Cell Development

1999 • 186 citations

Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions

2005 • 171 citations

Cutting Edge: NKT Cell Development Is Selectively Impaired in Fyn- Deficient Mice

1999 • 167 citations

Positive selection of V beta 8+ CD4-8- thymocytes by class I molecules expressed by hematopoietic cells.

1993 • 165 citations

Differential Requirement for Rel/Nuclear Factor κB Family Members in Natural Killer T Cell Development

2003 • 158 citations

Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes.

1994 • 155 citations

Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development.

1997 • 153 citations

NIK-dependent RelB Activation Defines a Unique Signaling Pathway for the Development of Vα14i NKT Cells

2003 • 120 citations

DOCK2 Is Essential for Antigen-Induced Translocation of TCR and Lipid Rafts, but Not PKC-θ and LFA-1, in T Cells

2003 • 116 citations

The Adaptor Protein AP-3 Is Required for CD1d-Mediated Antigen Presentation of Glycosphingolipids and Development of Vα14i NKT Cells

2003 • 113 citations

Thymocyte expression of cathepsin L is essential for NKT cell development

2002 • 110 citations

Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins

1999 • 99 citations

The CDM protein DOCK2 in lymphocyte migration

2002 • 87 citations

Developmental program of mouse Vα14i NKT cells

2005 • 85 citations

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

2005 • 46 citations

Development of CD1d‐restricted NKT cells in the mouse thymus

2004 • 44 citations

Restoration of NK T Cell Development infyn-Mutant Mice by a TCR Reveals a Requirement for Fyn During Early NK T Cell Ontogeny

2004 • 27 citations

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