Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

1997 • 2,370 citations

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

MOUSE CD1-SPECIFIC NK1 T CELLS: Development, Specificity, and Function

1997 • 1,326 citations

Requirement for V _α 14 NKT Cells in IL-12-Mediated Rejection of Tumors

1997 • 1,226 citations

Cutting Edge: Cross-Talk Between Cells of the Innate Immune System: NKT Cells Rapidly Activate NK Cells

1999 • 856 citations

CD1d-mediated Recognition of an α-Galactosylceramide by Natural Killer T Cells Is Highly Conserved through Mammalian Evolution

1998 • 649 citations

Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes

1998 • 642 citations

The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

1999 • 624 citations

Structure-Activity Relationship of .alpha.-Galactosylceramides against B16-Bearing Mice

1995 • 569 citations

Mouse CD94/NKG2A Is a Natural Killer Cell Receptor for the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule Qa-1b

1998 • 491 citations

Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Vα14 NKT cells

1998 • 474 citations

α/β–T Cell Receptor (TCR)+CD4−CD8− (NKT) Thymocytes Prevent Insulin-dependent Diabetes Mellitus in Nonobese Diabetic (NOD)/Lt Mice by the Influence of Interleukin (IL)-4 and/or IL-10

1998 • 473 citations

Murine CD1d-Restricted T Cell Recognition of Cellular Lipids

2000 • 467 citations

Detection of Antigen-Specific T Cells with Multivalent Soluble Class II MHC Covalent Peptide Complexes

1998 • 465 citations

CD1d-restricted Recognition of Synthetic Glycolipid Antigens by Human Natural Killer T Cells

1998 • 445 citations

Natural Ligand of Mouse CD1d1: Cellular Glycosylphosphatidylinositol

1998 • 399 citations

CD1d-Restricted Immunoglobulin G Formation to GPI-Anchored Antigens Mediated by NKT Cells

1999 • 386 citations

CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice.

1995 • 384 citations

Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes.

1998 • 383 citations

Initiation of Signal Transduction through the T Cell Receptor Requires the Multivalent Engagement of Peptide/MHC Ligands

1998 • 379 citations

KRN7000, a novel immunomodulator, and its antitumor activities.

1995 • 361 citations

Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype.

1999 • 359 citations

Early quantitative and functional deficiency of NK1⁺‐like thymocytes in the NOD mouse

1996 • 359 citations

Tissue-Specific Segregation of CD1d-Dependent and CD1d-Independent NK T Cells

1999 • 332 citations

Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells

2000 • 330 citations

Selective Ability of Mouse CD1 to Present Glycolipids: α-Galactosylceramide Specifically Stimulates Vα14+ NK T Lymphocytes

1998 • 319 citations

Bone Marrow NK1.1− and NK1.1+ T Cells Reciprocally Regulate Acute Graft versus Host Disease

1999 • 312 citations

Selective reduction of T cells bearing invariant V alpha 24J alpha Q antigen receptor in patients with systemic sclerosis.

1995 • 310 citations

Direct Assessment of MHC Class I Binding by Seven Ly49 Inhibitory NK Cell Receptors

1999 • 308 citations

Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis

1999 • 306 citations

Production of soluble MHC class II proteins with covalently bound single peptides

1994 • 302 citations

Cutting Edge: Activation of NK T Cells by CD1d and α-Galactosylceramide Directs Conventional T Cells to the Acquisition of a Th2 Phenotype

1999 • 296 citations

A New Look at T Cells

1998 • 269 citations

Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

1996 • 268 citations

NKT cells are phenotypically and functionally diverse

1999 • 259 citations

The Relationship of MHC-Peptide Binding and T Cell Activation Probed Using Chemically Defined MHC Class II Oligomers

2000 • 254 citations

Peptide Binding and Presentation by Mouse CD1

1995 • 252 citations

Tetrameric Complexes of Human Histocompatibility Leukocyte Antigen (HLA)-G Bind to Peripheral Blood Myelomonocytic Cells

1999 • 252 citations

NK Markers Are Expressed on a High Percentage of Virus-Specific CD8+ and CD4+ T Cells

2000 • 250 citations

Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice

1998 • 233 citations

NK1.1+ T Cells in the Liver Arise in the Thymus and Are Selected by Interactions with Class I Molecules on CD4+CD8+ Cells

2000 • 217 citations

Treatment of hepatic metastasis of the colon26 adenocarcinoma with an alpha-galactosylceramide, KRN7000.

1998 • 164 citations

Inhibition of T Helper Cell Type 2 Cell Differentiation and Immunoglobulin E Response by Ligand-Activated Vα14 Natural Killer T Cells

1999 • 158 citations

Binding and Antigen Presentation of Ceramide-Containing Glycolipids by Soluble Mouse and Human Cd1d Molecules

1999 • 154 citations

A role for CD4+ NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection.

1996 • 154 citations

Mouse CD1-Autoreactive T Cells Have Diverse Patterns of Reactivity to CD1+ Targets

1998 • 152 citations

α-Galactosylceramide Induces Early B-Cell Activation through IL-4 Production by NKT Cells

2000 • 141 citations

A Defect in Interleukin 12–Induced Activation and Interferon γ Secretion of Peripheral Natural Killer T Cells in Nonobese Diabetic Mice Suggests New Pathogenic Mechanisms for Insulin-Dependent Diabetes Mellitus

1999 • 136 citations

Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors

2000 • 133 citations

Induction of IFN-γ-producing CD4+ natural killer T cells byMycobacterium bovis bacillus Calmette Guérin

1999 • 126 citations

Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers

2000 • 88 citations

Heterogeneity of NK1.1+ T Cells in the Bone Marrow: Divergence from the Thymus

1999 • 78 citations

The Qa-1b molecule binds to a large subpopulation of murine NK cells

1998 • 76 citations

IL-4 secretion by CD4+ NK1+ T cells induces monocyte chemoattractant protein-1 in early listeriosis.

1997 • 76 citations

Diverse CD1d-restricted reactivity patterns of human T cells bearing “invariant” AV24BV11 TCR

1998 • 68 citations

The Murine Nonclassical Class I Major Histocompatibility Complex–like CD1.1 Molecule Protects Target Cells from Lymphokine-activated Killer Cell Cytolysis

1999 • 40 citations

A population of CD62Llow NK1.1− CD4+ T cells that resembles NK1.1+ CD4+ T cells

1998 • 25 citations

Enhancing Effects of Agelasphin-11 on Natural Killer Cell Activities of Normal and Tumor-Bearing Mice.

1996 • 13 citations