Positive selection of V beta 8+ CD4-8- thymocytes by class I molecules expressed by hematopoietic cells.

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

1990 • 885 citations

Mice lacking MHC class II molecules

1991 • 869 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Depletion of CD4 ⁺ T Cells in Major Histocompatibility Complex Class II-Deficient Mice

1991 • 673 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

CDlb restricts the response of human CD4−8−T lymphocytes to a microbial antigen

1992 • 577 citations

Specificity and function of T cells bearing γδ receptors

1988 • 570 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

Recognition of cluster of differentiation 1 antigens by human CD4−CD8>− cytolytic T lymphocyte

1989 • 521 citations

Stimulation of a major subset of lymphocytes expressing T cell receptor γδ by an antigen derived from mycobacterium tuberculosis

1989 • 491 citations

A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family

1987 • 397 citations

Correlations between T-cell specificity and the structure of the antigen receptor

1986 • 375 citations

Germ-line transmission of a disrupted β2microglobulin gene produced by homologous recombination in embryonic stem cells

1989 • 355 citations

The effect of thymus environment on T cell development and tolerance

1988 • 330 citations

Identity of cells that imprint H–2-restricted T-cell specificity in the thymus

1986 • 267 citations

Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes.

1987 • 230 citations

The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens

1989 • 219 citations

Predominant use of a Vα gene segment in mouse T-cell receptors for cytochrome c

1986 • 206 citations

H-2M3 presents a listeria monocytogenes peptide to cytotoxic T lymphocytes

1992 • 203 citations

Thymic selection: a matter of life and death

1992 • 184 citations

Positive selection of CD4+ thymocytes controlled by MHC class II gene products

1988 • 174 citations

Cytokine production by mature and immature CD4-CD8- T cells. Alpha beta-T cell receptor+ CD4-CD8- T cells produce IL-4.

1992 • 167 citations

An unusual lineage of alpha/beta T cells that contains autoreactive cells.

1991 • 152 citations

Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice.

1992 • 147 citations

Molecules Related to Class-I Major Histocompatibility Complex Antigens

1990 • 146 citations

Positive selection determines T cell receptor V beta 14 gene usage by CD8+ T cells.

1989 • 146 citations

Functionally conformed free class I heavy chains exist on the surface of beta 2 microglobulin negative cells.

1992 • 146 citations

Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice.

1988 • 142 citations

Specialized Role for a Murine Class I-b MHC Molecule in Prokaryotic Host Defenses

1992 • 135 citations

Inefficient positive selection of T cells directed by haematopoietic cells

1992 • 132 citations

Tolerance-related V beta clonal deletions in normal CD4-8-, TCR-alpha/beta + and abnormal lpr and gld cell populations.

1989 • 127 citations

Influence of the Major Histocompatibility Complex on Positive Thymic Selection of V_β17a⁺T Cells

1989 • 110 citations

Phenotype, ontogeny, and repertoire of CD4-CD8- T cell receptor alpha beta + thymocytes. Variable influence of self-antigens on T cell receptor V beta usage.

1991 • 107 citations

Phenotypic properties, interleukin 2 production, and developmental origin of a "mature" subpopulation of Lyt-2- L3T4- mouse thymocytes.

1987 • 76 citations

Tolerogenicity of thymic epithelium

1990 • 74 citations

Major histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes.

1992 • 70 citations

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny.

1992 • 67 citations

T‐Cell Lineages, Repertoire Selection and Tolerance Induction

1988 • 67 citations

Intrathymic selection of murine TCRαβ⁺CD4⁻CD8⁻ thymocytes

1990 • 50 citations

CD4⁻CD8⁻ thymocytes that express the T cell receptor may have previously expressed CD8

1990 • 41 citations

Functional responsiveness in vitro and in vivo of α/β T cell receptors expressed by the B2A2 (J11d)^– subset of CD4^–8^– thymocytes

1989 • 18 citations

Mouse strain differences in subset distribution and T cell antigen receptor expression among CD4⁻CD8⁻ thymocytes

1988 • 7 citations