Chronic neutropenia mediated by Fas ligand

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

The Fas Death Factor

1995 • 4,070 citations

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1995 • 1,477 citations

Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity

1995 • 1,306 citations

Characteristics of human large granular lymphocytes and relationship to natural killer and K cells

1981 • 1,008 citations

Clonal diseases of large granular lymphocytes [see comments]

1993 • 710 citations

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

1995 • 706 citations

Fas ligand in human serum

1996 • 682 citations

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1995 • 656 citations

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

1996 • 574 citations

Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro

1995 • 505 citations

Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells.

1998 • 453 citations

Clinical spectrum of clonal proliferations of T-large granular lymphocytes: a T-cell clonopathy of undetermined significance?

1994 • 267 citations

Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry

1994 • 226 citations

Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events.

1997 • 167 citations

Lectin-dependent and anti-CD3 induced cytotoxicity are preferentially mediated by peripheral blood cytotoxic T lymphocytes expressing Leu-7 antigen.

1986 • 164 citations

CD3+, CD56+ aggressive variant of large granular lymphocyte leukemia [see comments]

1994 • 147 citations

Treatment of large granular lymphocyte leukemia with oral low-dose methotrexate

1994 • 147 citations

Dysregulation of CD95/CD95 Ligand-Apoptotic Pathway in CD3+ Large Granular Lymphocyte Leukemia

1998 • 147 citations

Soluble Fas (APO‐1, CD95) and soluble Fas ligand in rheumatic diseases

1997 • 144 citations

Clinical spectrum of clonal proliferations of T-large granular lymphocytes: a T-cell clonopathy of undetermined significance?

1994 • 143 citations

Critical role of Lyn kinase in inhibition of neutrophil apoptosis by granulocyte-macrophage colony-stimulating factor.

1996 • 127 citations

CD3+, CD56+ aggressive variant of large granular lymphocyte leukemia [see comments]

1994 • 110 citations

Neutropenia Associated With T-Cell Large Granular Lymphocyte Leukemia: Long-Term Response to Cyclosporine Therapy Despite Persistence of Abnormal Cells

1998 • 96 citations

Immunogenetic similarities between patients with Felty's syndrome and those with clonal expansions of large granular lymphocytes in rheumatoid arthritis

1997 • 84 citations

Constitutive expression of Fas ligand in large granular lymphocyte leukaemia

1997 • 78 citations

The large granular lymphocyte syndrome with rheumatoid arthritis. immunogenetic evidence for a broader definition of felty's syndrome

1994 • 67 citations

Perforin gene expression in granular lymphocyte proliferative disorders

1990 • 52 citations

Analysis of the T cell receptor in the lymphoproliferative disease of granular lymphocytes: superantigen activation of clonal CD3+ granular lymphocytes.

1995 • 50 citations

Multidrug resistance analysis in lymphoproliferative disease of large granular lymphocytes

1998 • 35 citations

Increased lymphocyte apoptosis in Fas ligand transgenic mice.

1997 • 34 citations