Cyclin-Dependent Kinase Inhibitors of Saccharomyces cerevisiae and Schizosaccharomyces pombe

The molecular biology of the yeast saccharomyces: Life cycle and inheritance

1982 • 1,361 citations

The molecular biology of the yeast saccharomyces

1982 • 1,165 citations

The molecular biology of the yeast saccharomyces: Metabolism and gene expression

1983 • 1,118 citations

MAP kinase pathways in yeast: For mating and more

1995 • 1,009 citations

Inhibition of cyclin-dependent kinases by p21.

1995 • 999 citations

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Purification and properties of an ATP-dependent nucleosome remodeling factor

1995 • 600 citations

The Saccharomyces cerevisiae Cell Cycle

1981 • 539 citations

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

1993 • 521 citations

Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins.

1993 • 509 citations

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

1993 • 483 citations

Current topics in Microbiology and Immunology

1976 • 463 citations

The LIM domain is a modular protein-binding interface

1994 • 450 citations

The fission yeast cdc18+ gene product couples S phase to START and mitosis

1993 • 446 citations

The Yeast Cell Cycle Gene CDC34 Encodes a Ubiquitin-Conjugating Enzyme

1988 • 435 citations

Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2

1990 • 401 citations

Sequential gene function in the initiation of Saccharomyces cerevisiae DNA synthesis

1974 • 394 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

CLB5: a novel B cyclin from budding yeast with a role in S phase.

1992 • 391 citations

Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28.

1985 • 370 citations

Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85

1994 • 361 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

The PH084 Gene of Saccharomyces cerevisiae Encodes an Inorganic Phosphate Transporter

1991 • 350 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae.

1995 • 337 citations

Regulation of PHO4 Nuclear Localization by the PHO80-PHO85 Cyclin-CDK Complex

1996 • 326 citations

A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae

1989 • 298 citations

p34^Cdc28-Mediated Control of Cln3 Cyclin Degradation

1995 • 293 citations

Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.

1992 • 292 citations

FAR1 links the signal transduction pathway to the cell cycle machinery in yeast

1993 • 290 citations

A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins.

1996 • 285 citations

Isolation and Characterization of Acid Phosphatase Mutants in Saccharomyces cerevisiae

1973 • 276 citations

STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes.

1989 • 274 citations

FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.

1993 • 274 citations

A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5.

1993 • 270 citations

p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast

1995 • 259 citations

Direct Inhibition of the Yeast Cyclin-Dependent Kinase Cdc28-Cln by Far1

1994 • 258 citations

Progress in Cell Cycle Research

1997 • 243 citations

Phosphate-Regulated Inactivation of the Kinase PHO80-PHO85 by the CDK Inhibitor PHO81

1994 • 239 citations

Polarization of yeast cells in spatial gradients of alpha mating factor.

1993 • 237 citations

An Inhibitor of p34 ^CDC28 Protein Kinase Activity from Saccharomyces cerevisiae

1993 • 236 citations

Linkage of Replication to Start by the Cdk Inhibitor Sic1

1996 • 230 citations

Rapid Degradation of the G ₁ Cyclin Cln2 Induced by CDK-Dependent Phosphorylation

1996 • 227 citations

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

1995 • 213 citations

FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction.

1991 • 211 citations

Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal

1990 • 209 citations

Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins.

1995 • 185 citations

Far1 and Fus3 link the mating pheromone signal transduction pathway to three G1-phase Cdc28 kinase complexes.

1993 • 174 citations

Dual regulation of the yeast CDC28-p40 protein kinase complex: Cell cycle, pheromone, and nutrient limitation effects

1987 • 166 citations

An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells.

1994 • 164 citations

The two positively acting regulatory proteins PHO2 and PHO4 physically interact with PHO5 upstream activation regions.

1989 • 160 citations

Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila.

1993 • 158 citations

Signal Propagation and Regulation in the Mating Pheromone Response Pathway of the Yeast Saccharomyces cerevisiae

1994 • 157 citations

The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start.

1996 • 151 citations

Negative regulation of FAR1 at the Start of the yeast cell cycle.

1993 • 148 citations

Pheromone-dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation.

1991 • 148 citations

FAR1 is required for oriented polarization of yeast cells in response to mating pheromones.

1995 • 144 citations

P40SDB25, a putative CDK inhibitor, has a role in the M/G1 transition in Saccharomyces cerevisiae.

1994 • 142 citations

Regulatory Circuits for Gene Expression: The Metabolism of Galactose and Phosphate

1982 • 141 citations

PHO85, a negative regulator of the PHO system, is a homolog of the protein kinase gene, CDC28, of Saccharomyces cerevisiae

1988 • 141 citations

Mcm1 Is Required To Coordinate G₂-Specific Transcription in Saccharomyces cerevisiae

1995 • 131 citations

The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition.

1994 • 130 citations

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

1996 • 129 citations

A conserved mitotic kinase active at late anaphase—telophase in syncytial Drosophila embryos

1993 • 128 citations

Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae.

1994 • 126 citations

The product of the Saccharomyces cerevisiae cell cycle gene DBF2 has homology with protein kinases and is periodically expressed in the cell cycle.

1990 • 124 citations

A new role for MCM1 in yeast: cell cycle regulation of SW15 transcription.

1991 • 123 citations

B-type cyclins regulate G1 progression in fission yeast in opposition to the p25rum1 cdk inhibitor.

1996 • 115 citations

Function of the PHO regulatory genes for repressible acid phosphatase synthesis in Saccharomyces cerevisiae

1989 • 113 citations

Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients.

1995 • 110 citations

Chemical kinetic theory: understanding cell-cycle regulation

1996 • 100 citations

The transcription factor, the Cdk, its cyclin and their regulator: directing the transcriptional response to a nutritional signal.

1994 • 100 citations

Genes that can bypass the CLN requirement for Saccharomyces cerevisiae cell cycle START.

1994 • 97 citations

Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe.

1996 • 96 citations

A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle.

1993 • 95 citations

Cell Cycle-Regulated Transcription of the CLB2 Gene Is Dependent on Mcm1 and a Ternary Complex Factor

1995 • 95 citations

A B-type cyclin negatively regulates conjugation via interacting with cell cycle ‘start’ genes in fission yeast.

1994 • 92 citations

Functional Domains of Pho81p, an Inhibitor of Pho85p Protein Kinase, in the Transduction Pathway of P_i Signals in Saccharomyces cerevisiae

1995 • 91 citations

Start-Specific Transcription in Yeast

1996 • 88 citations

Regulation of repressible acid phosphatase gene transcription in Saccharomyces cerevisiae.

1985 • 87 citations

Specification of sites for polarized growth in Saccharomyces cerevisiae and the influence of external factors on site selection.

1992 • 86 citations

Interaction between the Cig1 and Cig2 B-type cyclins in the fission yeast cell cycle.

1994 • 80 citations

Isolation and characterization of recessive, constitutive mutations for repressible acid phosphatase synthesis in Saccharomyces cerevisiae

1975 • 77 citations

Negative regulators of the PHO system inSaccharomyces cerevisiae: isolation and structural characterization ofPHO85

1987 • 74 citations

A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism

1994 • 74 citations

A gene controlling the synthesis of non specific alkaline phosphatase in Saccharomyces cerevisiae

1976 • 70 citations

Requirement of Saccharomyces cerevisiae Ras for Completion of Mitosis

1995 • 70 citations

FAR1 is required for posttranscriptional regulation of CLN2 gene expression in response to mating pheromone.

1993 • 66 citations

Progress in Cell Cycle Research

1995 • 65 citations

Phosphorylation of FAR1 in response to alpha-factor: a possible requirement for cell-cycle arrest.

1992 • 65 citations

The cell-cycle-regulated budding yeast gene DBF2, encoding a putative protein kinase, has a homologue that is not under cell-cycle control

1991 • 64 citations

Functional Redundancy in the Yeast Cell Cycle: FUS3 and KSS1 Have Both Overlapping and Unique Functions

1991 • 63 citations

FAR1 and the G₁ Phase Specificity of Cell Cycle Arrest by Mating Factor in Saccharomyces cerevisiae

1995 • 61 citations

C-myc and the yeast transcription factor PHO4 share a common CACGTG-binding motif.

1991 • 59 citations

Functional domains of the yeast STE12 protein, a pheromone-responsive transcriptional activator.

1993 • 58 citations

Segregation of Unreplicated Chromosomes in Saccharomyces cerevisiae Reveals a Novel G₁/M-Phase Checkpoint

1995 • 51 citations

Negative Regulation of G₁ and G₂ by S-Phase Cyclins of Saccharomyces cerevisiae

1995 • 38 citations

Promoter analysis of the PHO81 gene encoding a 134 kDa protein bearing ankyrin repeats in the phosphatase regulon of Saccharomyces cerevisiae

1993 • 34 citations

Interaction of cdc2 and rum1 regulates Start and S-phase in fission yeast

1995 • 29 citations

Molecular and Expression Analysis of the Negative Regulators Involved in the Transcriptional Regulation of Acid Phosphatase Production in Saccharomyces cerevisiae

1990 • 23 citations