STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Methods in yeast genetics

1979 • 7,824 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

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1984 • 1,649 citations

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

1986 • 1,264 citations

Potential Metal-Binding Domains in Nucleic Acid Binding Proteins

1986 • 1,096 citations

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

1988 • 830 citations

Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae.

1981 • 542 citations

Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae

1984 • 501 citations

The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein

1989 • 491 citations

The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway

1987 • 431 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone.

1980 • 368 citations

GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

1987 • 365 citations

Respiration-deficient mutants of yeast

1964 • 357 citations

Nucleotide sequences of STE2 and STE3 , cell type-specific sterile genes from Saccharomyces cerevisiae

1985 • 351 citations

The yeast cell-type-specific repressor α2 acts cooperatively with a non-cell-type-specific protein

1988 • 348 citations

Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins

1984 • 341 citations

Saccharomyces cerevisiae protein involved in plasmid maintenance is necessary for mating of MATα cells

1988 • 323 citations

Yeast HAP1 activator binds to two upstream activation sites of different sequence

1987 • 317 citations

Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16.

1988 • 289 citations

Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae.

1987 • 253 citations

Conjugation in Saccharomyces cerevisiae

1988 • 248 citations

MATα1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes

1987 • 236 citations

A yeast operator overlaps an upstream activation site

1987 • 200 citations

Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast

1985 • 192 citations

Nucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases.

1986 • 189 citations

Control of yeast cell type by the mating type locus

1981 • 180 citations

Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II)

1987 • 158 citations

Yeast peptide pheromones, a-factor and α-factor, activate a common response mechanism in their target cells

1986 • 137 citations

Mutations in a gene encoding the alpha subunit of a Saccharomyces cerevisiae G protein indicate a role in mating pheromone signaling.

1988 • 121 citations

The human c-fos serum response factor and the yeast factors GRM/PRTF have related DNA-binding specificities.

1988 • 117 citations

Role of STE genes in the mating factor signaling pathway mediated by GPA1 in Saccharomyces cerevisiae.

1988 • 107 citations

Intracellular targeting and import of an F1-ATPase beta-subunit-beta-galactosidase hybrid protein into yeast mitochondria.

1984 • 102 citations

Identification of a DNA segment that is necessary and sufficient for alpha-specific gene control in Saccharomyces cerevisiae: implications for regulation of alpha-specific and a-specific genes.

1988 • 95 citations

Yeast STE7, STE11, and STE12 genes are required for expression of cell-type-specific genes.

1988 • 92 citations

Multiple regulation of STE2, a mating-type-specific gene of Saccharomyces cerevisiae.

1986 • 88 citations

Common signal transduction system shared by STE2 and STE3 in haploid cells of Saccharomyces cerevisiae : autocrine cell-cycle arrest results from forced expression of STE2

1987 • 80 citations

The Yeast Repeated Element Sigma Contains a Hormone-Inducible Promoter

1987 • 77 citations

Regulation by the Yeast Mating-Type Locus of STE12, a Gene Required for Cell-Type-Specific Expression

1987 • 72 citations

Studies on transposable elements in yeast. I. ROAM mutations causing increased expression of yeast genes: their activation by signals directed toward conjugation functions and their formation by insertion of Ty1 repetitive elements. II. deletions, duplications, and transpositions of the COR segment that encompasses the structural gene of yeast iso-1-cytochrome c.

1981 • 67 citations

Identification of a Ty1 regulatory sequence responsive to STE7 and STE12.

1988 • 64 citations

Interactions of purified transcription factors: binding of yeast MAT alpha 1 and PRTF to cell type-specific, upstream activating sequences.

1988 • 62 citations

Studies on Transposable Elements in Yeast: I. ROAM Mutations Causing Increased Expression of Yeast Genes: Their Activation by Signals Directed toward Conjugation Functions and Their Formation by Insertion of Tyl Repetitive Elements

1981 • 54 citations

Induction of yeast mating pheromone a-factor by α cells

1983 • 52 citations

Cell-type-dependent gene activation by yeast transposon Ty1 involves multiple regulatory determinants.

1987 • 34 citations

AAAS--Philip Hauge Abelson Prize: To Be Awarded to a Public Servant or Scientist

1986 • 1 citations