Start-Specific Transcription in Yeast

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

The regulation of transcription by phosphorylation

1992 • 1,316 citations

Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

1976 • 906 citations

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1994 • 902 citations

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

1994 • 759 citations

Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast

1981 • 740 citations

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.

1992 • 587 citations

An essential G1 function for cyclin-like proteins in yeast

1989 • 574 citations

The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog.

1988 • 563 citations

Regulation of the Yeast HO Gene

1985 • 526 citations

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

1993 • 521 citations

Hundreds of ankyrin‐like repeats in functionally diverse proteins: Mobile modules that cross phyla horizontally?

1993 • 504 citations

The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast.

1994 • 502 citations

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.

1993 • 492 citations

Substrates for p34cdc2: In vivo veritas?

1990 • 472 citations

G1-specific cyclins of S. cerevisiae: Cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase

1990 • 449 citations

The fission yeast cdc18+ gene product couples S phase to START and mitosis

1993 • 446 citations

DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae.

1988 • 445 citations

The retinoblastoma protein binds to a family of E2F transcription factors.

1993 • 436 citations

The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor

1994 • 432 citations

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

1994 • 426 citations

A Role for the Transcription Factors Mbp1 and Swi4 in Progression from G1 to S Phase

1993 • 399 citations

Cell cycle control of the yeast HO gene: Cis- and Trans-acting regulators

1987 • 392 citations

The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues.

1993 • 391 citations

CLB5: a novel B cyclin from budding yeast with a role in S phase.

1992 • 391 citations

The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2.

1993 • 377 citations

Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins

1993 • 376 citations

Binding of myc proteins to canonical and noncanonical DNA sequences.

1993 • 375 citations

Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila

1987 • 366 citations

Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85

1994 • 361 citations

Identification of Ets- and Notch-Related Subunits in GA Binding Protein

1991 • 358 citations

The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast

1991 • 354 citations

A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle

1991 • 341 citations

Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F.

1992 • 331 citations

DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control

1994 • 323 citations

Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription

1991 • 313 citations

Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.

1992 • 310 citations

A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis

1991 • 310 citations

Sequential function of gene products relative to DNA synthesis in the yeast cell cycle

1976 • 302 citations

A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae

1983 • 302 citations

Transcription mechanisms and regulation

1994 • 299 citations

Induction of pseudohyphal growth by overexpression of PHD1, a Saccharomyces cerevisiae gene related to transcriptional regulators of fungal development.

1994 • 289 citations

Molecular analysis of a cell lineage

1983 • 286 citations

Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.

1992 • 281 citations

Molecular Biology of the Fission Yeast

1989 • 261 citations

Direct Inhibition of the Yeast Cyclin-Dependent Kinase Cdc28-Cln by Far1

1994 • 258 citations

The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression.

1992 • 239 citations

An Inhibitor of p34 ^CDC28 Protein Kinase Activity from Saccharomyces cerevisiae

1993 • 236 citations

Control of DNA synthesis genes in fission yeast by the cell-cycle gene cdclO+

1992 • 233 citations

cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis.

1994 • 232 citations

Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 ‘start’ gene.

1985 • 228 citations

The identification of a second cell cycle control on the HO promoter in yeast: Cell cycle regulation of SWI5 nuclear entry

1990 • 215 citations

Coordination of expression of DNA synthesis genes in budding yeast by a cell-cycle regulated trans factor

1991 • 209 citations

The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription

1989 • 207 citations

Asymmetry and directionality in production of new cell types during clonal growth: the switching pattern of homothallic yeast

1979 • 206 citations

Positive feedback in the activation of Gl cyclins in yeast

1991 • 202 citations

Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F.

1993 • 196 citations

Transcription : mechanisms and regulation

1994 • 195 citations

StuA is required for cell pattern formation in Aspergillus.

1992 • 192 citations

A central role for SWI6 in modulating cell cycle Start-specific transcription in yeast

1992 • 191 citations

The HIP1 Binding Site Is Required for Growth Regulation of the Dihydrofolate Reductase Gene Promoter

1992 • 172 citations

Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene

1989 • 171 citations

SWI6 protein is required for transcription of the periodically expressed DNA synthesis genes in budding yeast

1992 • 169 citations

Dual regulation of the yeast CDC28-p40 protein kinase complex: Cell cycle, pheromone, and nutrient limitation effects

1987 • 166 citations

The PCL2 (ORFD)-PHO85 Cyclin-Dependent Kinase Complex: a Cell Cycle Regulator in Yeast

1994 • 164 citations

Regulation of mating in the cell cycle of Saccharomyces cerevisiae.

1977 • 156 citations

Cell Cycle Control by a Complex of the Cyclin HCS26 (PCL1) and the Kinase PHO85

1994 • 152 citations

Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division.

1992 • 143 citations

P40SDB25, a putative CDK inhibitor, has a role in the M/G1 transition in Saccharomyces cerevisiae.

1994 • 142 citations

Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity.

1992 • 140 citations

Anatomy of a transcription factor important for the Start of the cell cycle in Saccharomyces cerevisiae

1992 • 136 citations

A repetitive DNA sequence that confers cell-cycle START (CDC28)-dependent transcription of the HO gene in yeast

1985 • 134 citations

Complete transposition requires four active monomers in the mu transposase tetramer.

1994 • 125 citations

A new cdc gene required for S phase entry of Schizosaccharomyces pombe encodes a protein similar to the cdc 10+ and SWI4 gene products.

1992 • 122 citations

Characterization of a short, cis-acting DNA sequence which conveys cell cycle stage-dependent transcription in Saccharomyces cerevisiae.

1991 • 122 citations

Cell cycle control of DNA synthesis in budding yeast

1992 • 118 citations

At least 1400 base pairs of 5′-flanking DNA is required for the correct expression of the HO gene in yeast

1985 • 116 citations

Sct1 functions in partnership with Cdc10 in a transcription complex that activates cell cycle START and inhibits differentiation

1993 • 114 citations

Analysis of the SWI4/SWI6 protein complex, which directs G1/S-specific transcription in Saccharomyces cerevisiae.

1993 • 107 citations

SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase.

1993 • 104 citations

The CDC8 transcript is cell cycle regulated in yeast and is expressed coordinately with CDC9 and CDC21 at a point preceding histone transcription

1987 • 103 citations

KIN28, a yeast split gene coding for a putative protein kinase homologous to CDC28.

1986 • 96 citations

res2+, a new member of the cdc10+/SWI4 family, controls the ‘start’ of mitotic and meiotic cycles in fission yeast.

1994 • 94 citations

Isolation and transcriptional characterization of a morphological modifier: the Aspergillus nidulans stunted (stuA) gene

1991 • 93 citations

A B-type cyclin negatively regulates conjugation via interacting with cell cycle ‘start’ genes in fission yeast.

1994 • 92 citations

Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast.

1991 • 90 citations

Interaction of the yeast Swi4 and Swi6 cell cycle regulatory proteins in vitro.

1992 • 83 citations

Cell cycle-specific expression of the SWI4 transcription factor is required for the cell cycle regulation of HO transcription.

1991 • 82 citations

The isolation of new DNA synthesis mutants in the yeastSaccharomyces cerevisiae

1982 • 79 citations

Cell cycle-dependent transcription of CLN2 is conferred by multiple distinct cis-acting regulatory elements.

1994 • 78 citations

The Kin28 Protein Kinase is Associated with a Cyclin in Saccharomyces cerevisiae

1993 • 77 citations

pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe.

1994 • 71 citations

A cell cycle-responsive transcriptional control element and a negative control element in the gene encoding DNA polymerase alpha in Saccharomyces cerevisiae.

1991 • 70 citations

A NEW GENE AFFECTING THE EFFICIENCY OF MATING-TYPE INTERCONVERSIONS IN HOMOTHALLIC STRAINS OF SACCHAROMYCES CEREVISIAE

1977 • 69 citations

Role of Swi4 in cell cycle regulation of CLN2 expression.

1994 • 65 citations

Suppression of a yeast cyclic AMP-dependent protein kinase defect by overexpression of SOK1, a yeast gene exhibiting sequence similarity to a developmentally regulated mouse gene.

1994 • 53 citations

The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter.

1992 • 51 citations

Multiple SWI6-dependent cis-acting elements control SWI4 transcription through the cell cycle.

1993 • 48 citations

Taxonomy and Phylogenesis

1989 • 46 citations

The Schizosaccharomyces pombe MBF Complex Requires Heterodimerization for Entry into S Phase

1995 • 45 citations

Cytoskeletal and DNA structure abnormalities result from bypass of requirement for the cdc10 start gene in the fission yeast Schizosaccharomyces pombe

1992 • 42 citations

Mutational analysis supports a structural model for the cell cycle protein kinase p34

1994 • 42 citations

Characterization of the fission yeast cdc10 + protein that is required for commitment to the cell cycle

1989 • 41 citations

Direct induction of G1-specific transcripts following reactivation of the Cdc28 kinase in the absence of de novo protein synthesis.

1992 • 41 citations

The activity of S.pombe DSC-1-like factor is cell cycle regulated and dependent on the activity of p34cdc2.

1993 • 39 citations

DNA synthesis control in yeast: An evolutionarily conserved mechanism for regulating DNA synthesis genes?

1992 • 37 citations

Mutations in the cdc10 start gene of Schizosaccbaromyces pombe implicate the region of homology between cdc10 and SWl6 as important for p85cdc10 function

1992 • 35 citations

SWI6 is a regulatory subunit of two different cell cycle START-dependent transcription factors in Saccharomyces cerevisiae

1992 • 28 citations

Three independent forms of regulation affect expression of HO, CLN1 and CLN2 during the cell cycle of Saccharomyces cerevisiae.

1994 • 23 citations

Mutational analysis of a DNA sequence involved in linking gene expression to the cell cycle

1992 • 22 citations

Mutation Analysis ofSaccharomyces cerevisiae CDC6Promoter: Defining Its UAS Domain and Cell Cycle Regulating Element

1993 • 13 citations

Multiple elements regulate expression of the cell cycle-regulated thymidylate synthase gene of Saccharomyces cerevisiae

1988 • 8 citations