Secretion in yeast: structural features influencing the post-translational translocation of prepro-alpha-factor in vitro.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Signal sequences

1985 • 2,179 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

Mechanism of Protein Translocation Across the Endoplasmic Reticulum Membrane

1986 • 509 citations

Glycosylation and processing of prepro-α-factor through the yeast secretory pathway

1984 • 410 citations

The Assembly of Proteins into Biological Membranes: The Membrane Trigger Hypothesis

1979 • 408 citations

In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent post-translational translocation of the prepro-α-factor

1986 • 332 citations

Secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires ATP hydrolysis.

1986 • 315 citations

Heterologous Protein Secretion from Yeast

1985 • 299 citations

Secretion in yeast: Reconstitution of the translocation and glycosylation of α-factor and invertase in a homologous cell-free system

1986 • 216 citations

An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast.

1983 • 187 citations

Secretion in yeast: translocation and glycosylation of prepro-α-factor in vitro can occur via an ATP-dependent post-translational mechanism

1986 • 185 citations

Saccharomyces cerevisiaecontains two discrete genes coding for the α-factor pheromone

1983 • 165 citations

Using Recombinant DNA Techniques to Study Protein Targeting in the Eucaryotic Cell

1985 • 158 citations

The transmembrane segment of the human transferrin receptor functions as a signal peptide.

1986 • 151 citations

Determinants for protein localization: beta-lactamase signal sequence directs globin across microsomal membranes.

1984 • 149 citations

Translation arrest by oligodeoxynucleotides complementary to mRNA coding sequences yields polypeptides of predetermined length

1986 • 142 citations

Secretion of foreign proteins from Saccharomyces cerevisiae directed by alpha-factor gene fusions.

1984 • 126 citations

Import of honeybee prepromelittin into the endoplasmic reticulum: structural basis for independence of SRP and docking protein.

1987 • 113 citations

Import of frog prepropeptide GLa into microsomes requires ATP but does not involve docking protein or ribosomes.

1987 • 111 citations

The cytoplasmic carboxy terminus of M13 procoat is required for the membrane insertion of its central domain

1986 • 92 citations

Genes required for completion of import of proteins into the endoplasmic reticulum in yeast.

1984 • 86 citations

Protein translocation across the yeast microsomal membrane is stimulated by a soluble factor.

1986 • 80 citations

Semliki Forest Virus: A Probe for Membrane Traffic in the Animal Cell

1984 • 73 citations

Import of honeybee prepromelittin into the endoplasmic reticulum. Requirements for membrane insertion, processing, and sequestration.

1986 • 71 citations

Substrate recognition by oligosaccharyl transferase. Inhibition of co-translational glycosylation by acceptor peptides.

1983 • 71 citations

Protein transport and secretion

1983 • 69 citations

Transfer of Secretory Proteins through the Membrane of the Endoplasmic Reticulum

1986 • 58 citations

Recombinant forms of M13 procoat with an OmpA leader sequence or a large carboxy-terminal extension retain their independence of secY function.

1987 • 53 citations

In vitro biosynthesis, core glycosylation and membrane integration of opsin

1981 • 49 citations

Determinants for protein translocation across mammalian endoplasmic reticulum

1986 • 26 citations

Control of yeast alpha-specific genes: evidence for two blocks to expression in MATa/MAT alpha diploids.

1985 • 20 citations

Signal recognition particle causes a transient arrest in the biosynthesis of prepromelittin and mediates its translocation across mammalian endoplasmic reticulum.

1987 • 9 citations