Proline‐Directed Protein Kinase (p34^cdc2/p58^{cyclin A}) Phosphorylates Bovine Neurofilaments

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Radioiodination of proteins in single polyacrylamide gel slices. Tryptic peptide analysis of all the major members of complex multicomponent systems using microgram quantities of total protein.

1977 • 778 citations

Dominoes and Clocks: the Union of Two Views of the Cell Cycle

1989 • 750 citations

The enzymatic preparation of [α-32P]nucleoside triphosphates, cyclic [32P]AMP, and cyclic [32P]GMP

1979 • 574 citations

Two-stage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns

1987 • 503 citations

Intermediate filaments in nervous tissues

1978 • 502 citations

Substrates for p34cdc2: In vivo veritas?

1990 • 472 citations

Driving the cell cycle: M phase kinase, its partners, and substrates

1990 • 404 citations

Identification of the major multiphosphorylation site in mammalian neurofilaments.

1988 • 394 citations

Multiple phosphorylation sites in mammalian neurofilament polypeptides.

1982 • 381 citations

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

1990 • 364 citations

Neurofilament architecture combines structural principles of intermediate filaments with carboxy-terminal extensions increasing in size between triplet proteins.

1983 • 361 citations

Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin

1990 • 328 citations

The structure, biochemical properties, and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state.

1985 • 325 citations

The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments.

1983 • 291 citations

Structure of the peripheral domains of neurofilaments revealed by low angle rotary shadowing

1988 • 230 citations

SDS—PAGE strongly overestimates the molecular masses of the neurofilament proteins

1984 • 189 citations

Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments.

1988 • 177 citations

Identification of a Novel Proline-directed Serine/Threonine Protein Kinase in Rat Pheochromocytoma

1989 • 159 citations

Nerve growth factor regulates both the phosphorylation and steady-state levels of microtubule-associated protein 1.2 (MAP1.2).

1988 • 139 citations

The Neuronal Cytoskeleton

1992 • 132 citations

Phosphorylation of intermediate filament proteins by cAMP-dependent protein kinases

1981 • 128 citations

Phosphorylation of the amino-terminal head domain of the middle molecular mass 145-kDa subunit of neurofilaments. Evidence for regulation by second messenger-dependent protein kinases.

1990 • 126 citations

The structure of a human neurofilament gene (NF-L): A unique exon-intron organization in the intermediate filament gene family

1987 • 120 citations

Decomposition of phosphoserine and phosphothreonine during acid hydrolysis

1976 • 118 citations

In Vivo Phosphorylation of Distinct Domains of the 70-Kilodalton Neurofilament Subunit Involves Different Protein Kinases

1989 • 109 citations

Location and sequence characterization of the major phosphorylation sites of the high molecular mass neurofilament proteins M and H

1987 • 103 citations

The transport and assembly of the axonal cytoskeleton.

1989 • 97 citations

Study of the 10-nm-filament fraction isolated during the standard microtubule preparation

1980 • 93 citations

The complete amino acid sequence of the major mammalian neurofilament protein (NF‐L)

1985 • 93 citations

Expression of rat neurofilament proteins NF-L and NF-M in transfected non-neuronal cells.

1989 • 89 citations

Phosphorylation of bovine neurofilament proteins by protein kinase FA (glycogen synthase kinase 3)

1991 • 86 citations

What Controls the Cell Cycle

1991 • 82 citations

Nerve growth factor enhances the synthesis, phosphorylation, and metabolic stability of neurofilament proteins in PC12 cells.

1987 • 77 citations

Proline-directed protein phosphorylation and cell cycle regulation

1991 • 72 citations

Identification of actin nucleation activity and polymerization inhibitor in ameboid cells: their regulation by chemotactic stimulation.

1989 • 69 citations

Phosphorylation of neurofilament proteins by protein kinase C

1988 • 67 citations

Dynamic properties of intermediate filaments: Disassembly and reassembly during mitosis in baby hamster kidney cells

1990 • 66 citations

Characterization of the cytoplasmic proline-directed protein kinase in proliferative cells and tissues as a heterodimer comprised of p34cdc2 and p58cyclin A.

1991 • 63 citations

Phosphorylation of synapsin I at a novel site by proline-directed protein kinase.

1990 • 56 citations

Primary and Secondary Structure of IF Protein Chains and Modes of Molecular Aggregation

1990 • 20 citations

Physicochemical characterization of the 68,000-dalton protein of bovine neurofilaments

1984 • 20 citations