Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ.

1983 • 1,162 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

1983 • 1,162 citations

Intermediate Filaments: A Chemically Heterogeneous, Developmentally Regulated Class of Proteins

1982 • 1,021 citations

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons.

1975 • 937 citations

Radioiodination of proteins in single polyacrylamide gel slices. Tryptic peptide analysis of all the major members of complex multicomponent systems using microgram quantities of total protein.

1977 • 778 citations

Cross-linker system between neurofilaments, microtubules and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

1982 • 672 citations

All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody

1981 • 654 citations

Microtubule-Associated Proteins

1986 • 559 citations

Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton.

1984 • 496 citations

Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats

1987 • 490 citations

Control of axonal caliber by neurofilament transport.

1984 • 439 citations

Multiple phosphorylation sites in mammalian neurofilament polypeptides.

1982 • 381 citations

Protein phosphorylation in the nervous system

1984 • 329 citations

The structure, biochemical properties, and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state.

1985 • 325 citations

Five mouse tubulin isotypes and their regulated expression during development.

1985 • 323 citations

Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments.

1983 • 319 citations

Slow components of axonal transport: two cytoskeletal networks.

1980 • 318 citations

The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments.

1983 • 291 citations

Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons.

1986 • 248 citations

Antibodies against filamentous components in discrete cell types of the mouse retina

1984 • 233 citations

Antibody decoration of neurofilaments.

1981 • 226 citations

Stable polymers of the axonal cytoskeleton: the axoplasmic ghost.

1982 • 216 citations

Expression of neurofilament subunits in neurons of the central and peripheral nervous system: an immunohistochemical study with monoclonal antibodies

1986 • 206 citations

Modulations of neurofilament axonal transport during the development of rabbit retinal ganglion cells

1983 • 193 citations

Immunoelectronmicroscopical localization of the three neurofilament triplet proteins along neurofilaments of cultured dorsal root ganglion neurones

1982 • 190 citations

SDS—PAGE strongly overestimates the molecular masses of the neurofilament proteins

1984 • 189 citations

The differential appearance of neurofilament triplet polypeptides in the developing rat optic nerve

1984 • 175 citations

Microtubule assembly using the microtubule‐associated protein MAP‐2 prepared in defined states of phosphorylation with protein kinase and phosphatase

1983 • 163 citations

Modification of tubulin by tyrosylation in cells and extracts and its effect on assembly in vitro.

1977 • 158 citations

Bulk Preparation of CNS Cytoskeleton and the Separation of Individual Neurofilament Proteins by Gel Filtration: Dye‐Binding Characteristics and Amino Acid Compositions

1982 • 154 citations

Spectrin subtypes in mammalian brain: an immunoelectron microscopic study

1986 • 138 citations

Phosphate content of mammalian neurofilaments.

1982 • 135 citations

Posttranslational modification of neurofilament proteins by phosphate during axoplasmic transport in retinal ganglion cell neurons

1987 • 125 citations

Interval between the synthesis and assembly of cytoskeletal proteins in cultured neurons

1986 • 119 citations

Erythrocyte and Brain Forms of Spectrin in Cerebellum: Distinct Membrane-Cytoskeletal Domains in Neurons

1983 • 118 citations

Posttranslational modification of a neurofilament protein during axoplasmic transport: implications for regional specialization of CNS axons

1982 • 117 citations

Novel monoclonal antibodies provide evidence for the in situ existence of a nonphosphorylated form of the largest neurofilament subunit

1986 • 114 citations

Differential turnover of phosphate groups on neurofilament subunits in mammalian neurons in vivo.

1986 • 113 citations

Protein-chemical characterization of NF-H, the largest mammalian neurofilament component; intermediate filament-type sequences followed by a unique carboxy-terminal extension

1985 • 110 citations

Differential Expression of Microtubule Components during Brain Development

1986 • 110 citations

In Vivo Phosphorylation of Distinct Domains of the 70-Kilodalton Neurofilament Subunit Involves Different Protein Kinases

1989 • 109 citations

Phosphorylation of ankyrin decreases its affinity for spectrin tetramer.

1985 • 108 citations

Structural changes accompanying phosphorylation of tarantula muscle myosin filaments.

1987 • 106 citations

Neurofilaments, a Subclass of Intermediate Filaments: Structure and Expression

1983 • 103 citations

Microheterogeneity ("neurotypy") of neurofilament proteins.

1983 • 102 citations

CHARACTERIZATION OF MULTIPLE FORMS OF BRAIN TUBULIN SUBUNITS

1978 • 100 citations

Slow posttranslational modification of a neurofilament protein.

1985 • 92 citations

Characterization of posttranslational processing of the mammalian high-molecular-weight neurofilament protein in vivo.

1987 • 90 citations

Varying degrees of phosphorylation determine microheterogeneity of the heavy neurofilament polypeptide (Nf-H)

1987 • 86 citations

Early posttranslational modifications of the three neurofilament subunits in mouse retinal ganglion cells: neuronal sites and time course in relation to subunit polymerization and axonal transport

1989 • 79 citations

Preferential phosphorylation of the 150,000 molecular weight component of neurofilaments by a cyclic AMP-dependent, microtubule-associated protein kinase.

1981 • 76 citations

Protein degradation in the mouse visual system I. Degradation of axonally transported and retinal proteins

1980 • 74 citations

Appearance of new variants of membrane skeletal protein 4.1 during terminal differentiation of avian erythroid and lenticular cells

1985 • 73 citations

Characteristics of the protein kinase activity associated with rat neurofilament preparations

1983 • 69 citations

Posttranslational modification of neurofilament polypeptides in rabbit retina

1987 • 69 citations

Neurofilament protein phosphorylation. Species generality and reaction characteristics.

1982 • 67 citations

Neurofilament triplet proteins of NB2a/d1 neuroblastoma: posttranslational modification and incorporation into the cytoskeleton during differentiation

1988 • 65 citations

NEUROFILAMENTS

1979 • 65 citations

Characterization and Comparison of Neurofilament Proteins from Rat and Mouse CNS

1981 • 65 citations

A Comparison of In Vitro‐ and In Vivo Phosphorylated Neurofilament Polypeptides

1981 • 63 citations

The tubulins: From DNA to RNA to protein and back again

1983 • 63 citations

Studies on the biosynthesis of neurofilament proteins.

1980 • 61 citations

Multiple calcium-activated neutral proteinases (CANP) in mouse retinal ganglion cell neurons: specificities for endogenous neuronal substrates and comparison to purified brain CANP

1986 • 60 citations

Microtubule‐Associated Proteins in the Developing Brain

1986 • 55 citations

Isolation of rat liver microtubule-associated proteins. Evidence for a family of microtubule-associated proteins with molecular mass of around 200,000 which distribute widely among mammalian cells.

1988 • 53 citations

Axonal Polypeptides Cross‐Reactive with Antibodies to Neurofilament Proteins

1983 • 52 citations

Microheterogeneity of microtubule-associated proteins, MAP-1 and MAP-2, and differential phosphorylation of individual subcomponents.

1985 • 52 citations

Delayed phosphorylation of the largest neurofilament protein in rat optic nerve development

1986 • 48 citations

Limited proteolytic modification of a neurofilament protein involves a proteinase activated by endogenous levels of calcium

1983 • 46 citations

MICROHETEROGENEITY OF BRAIN CYTOPLASMIC AND SYNAPTOPLASMIC ACTINS

1978 • 46 citations

The patterns of expression of two ankyrin isoforms demonstrate distinct steps in the assembly of the membrane skeleton in neuronal morphogenesis

1984 • 45 citations

Posttranslational processing of alpha-tubulin during axoplasmic transport in CNS axons.

1982 • 41 citations

Chemical modification of charged amino acid moieties alters the electrophoretic mobilities of neurofilament subunits on SDS/polyacrylamide gels

1987 • 35 citations

Studies on the Biosynthesis of Intermediate Filament Proteins in the Rat CNS

1982 • 35 citations

Genetically determined protein polymorphism in the rabbit nervous system.

1976 • 30 citations

Increased Axonal Proteolysis in Myelin-Deficient Mutant Mice

1982 • 29 citations

Axonal maturation in development—II. Immunofluorescence study of rat spinal cord and cerebellum with axon‐specific neurofilament antibodies

1987 • 18 citations

Phosphorylation and Dephosphorylation of Neurofilament Proteins in Retinal Ganglion Cell Neurons In Vivo

1987 • 14 citations

Purification and Characterization of Myosin from Calf Brain

1983 • 14 citations

DIFFERENCES IN THE NEUROFILAMENT PROTEINS BETWEEN THE PERIKARYON AND AXON OF THE BOVINE SPINAL GANGLION

1984 • 14 citations