The structure of a human neurofilament gene (NF-L): A unique exon-intron organization in the intermediate filament gene family

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Selfish DNA: the ultimate parasite

1980 • 2,095 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Intermediate Filaments: A Chemically Heterogeneous, Developmentally Regulated Class of Proteins

1982 • 1,021 citations

The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons.

1975 • 937 citations

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

1983 • 743 citations

Intermediate filaments in nervous tissues

1978 • 502 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

On the origin of RNA splicing and introns

1985 • 483 citations

The molecular biology of intermediate filaments

1985 • 475 citations

The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins.

1982 • 432 citations

Multiple phosphorylation sites in mammalian neurofilament polypeptides.

1982 • 381 citations

Neurofilament architecture combines structural principles of intermediate filaments with carboxy-terminal extensions increasing in size between triplet proteins.

1983 • 361 citations

Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments

1983 • 336 citations

Intermediate filaments: Cell-type-specific markers in differentiation and pathology

1982 • 331 citations

The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins

1983 • 326 citations

The structure, biochemical properties, and immunogenicity of neurofilament peripheral regions are determined by phosphorylation state.

1985 • 325 citations

The actin genes of drosophila: Protein coding regions are highly conserved but intron positions are not

1981 • 322 citations

The construction of cosmid libraries which can be used to transform eukaryotic cells

1982 • 319 citations

Direct repeats flank three small nuclear RNA pseudogenes in the human genome

1981 • 307 citations

THE MOLECULAR GENETICS OF HUMAN HEMOGLOBINS

1980 • 306 citations

The cDNA sequence of a human epidermal keratin: Divergence of sequence but conservation of structure among intermediate filament proteins

1982 • 298 citations

The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments.

1983 • 291 citations

Processed genes: a dispersed human immunoglobulin gene bearing evidence of RNA-type processing

1982 • 235 citations

Isolation and characterization of a cloned rat insulin gene

1979 • 229 citations

The structure of the vimentin gene

1983 • 227 citations

Isolation and structural organization of the human preproenkephalin gene

1982 • 217 citations

Conversion of RNA to DNA in mammals: Alu-like elements and pseudogenes

1983 • 202 citations

Genetics, evolution, and expression of the 68,000-mol-wt neurofilament protein: isolation of a cloned cDNA probe.

1985 • 188 citations

Cassette of Eight Exons Shared by Genes for LDL Receptor and EGF Precursor

1985 • 185 citations

Cloning and developmental expression of the murine neurofilament gene family

1986 • 180 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum.

1986 • 165 citations

Intron–exon splice junctions map at protein surfaces

1982 • 148 citations

Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family

1985 • 138 citations

The genes coding for the cytoskeletal proteins actin and vimentin in warm-blooded vertebrates.

1982 • 136 citations

Intragenic amplification and divergence in the mouse α-fetoprotein gene

1981 • 117 citations

Characterization of the hamster desmin gene: Expression and formation of desmin filaments in nonmuscle cells after gene transfer

1985 • 112 citations

Protein-chemical characterization of NF-H, the largest mammalian neurofilament component; intermediate filament-type sequences followed by a unique carboxy-terminal extension

1985 • 110 citations

Hybrid character of a large neurofilament protein (NF-M): intermediate filament type sequence followed by a long and acidic carboxy-terminal extension.

1984 • 110 citations

Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis

1980 • 106 citations

Function and Evolution of Neurofilament Proteins^a

1985 • 101 citations

The complete amino acid sequence of the major mammalian neurofilament protein (NF‐L)

1985 • 93 citations

Evolution and structure of the fibrinogen genes

1985 • 85 citations

Identification of the subunit proteins of 10-nm neurofilaments isolated from axoplasm of squid and Myxicola giant axons.

1979 • 78 citations

The ovalbumin gene family: complete sequence and structure of the Y gene

1982 • 68 citations

An isoelectric variant of the 150,000-dalton neurofilament polypeptide. Evidence that phosphorylation state affects its association with the filament.

1984 • 66 citations

Intermediate filaments in non-neuronal cells of invertebrates: isolation and biochemical characterization of intermediate filaments from the esophageal epithelium of the mollusc Helix pomatia.

1985 • 58 citations

Cloning of a cDNA encoding the smallest neurofilament protein from the rat

1985 • 58 citations

Intermediate filaments in muscle and epithelial cells of nematodes.

1986 • 58 citations

Specific detection of neuronal cell bodies: in situ hybridization with a biotin-labeled neurofilament cDNA probe.

1986 • 55 citations

Complete sequence of a bovine type I cytokeratin gene: conserved and variable intron positions in genes of polypeptides of the same cytokeratin subfamily.

1985 • 52 citations

Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins.

1984 • 50 citations

Comparison of the human apolipoprotein genes

1985 • 32 citations