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The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins.

Data up to Jan 2025

Published1995
Citations479
References55

Total Citations Per Year

Abstract

References (55)

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

1985 • 824 citations

L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein

1992 • 790 citations

How profilin promotes actin filament assembly in the presence of thymosin β4

1993 • 532 citations

Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

1991 • 532 citations

Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose.

1994 • 484 citations

cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets.

1994 • 451 citations

Identification and characterization of a novel cytoskeleton-associated pp60src substrate.

1991 • 435 citations

A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin.

1992 • 411 citations

The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts.

1992 • 374 citations

Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton.

1992 • 344 citations

Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation

1984 • 319 citations

Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts

1994 • 282 citations

A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin-based cytoskeleton of mammalian cells.

1995 • 272 citations

Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators.

1990 • 270 citations

cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1.

1989 • 253 citations

Phosphorylation of Focal Adhesion Vasodilator‐Stimulated Phosphoprotein at Ser157 in Intact Human Platelets Correlates with Fibrinogen Receptor Inhibition

1994 • 251 citations

Mechanism of the interaction of human platelet profilin with actin.

1991 • 235 citations

Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP.

1995 • 208 citations

Evidence for a functional link between profilin and CAP in the yeast S. cerevisiae

1991 • 207 citations

The ActA protein of Listeria monocytogenes acts as a nucleator inducing reorganization of the actin cytoskeleton.

1994 • 188 citations

The three faces of profilin

1993 • 179 citations

Poly(<scp>l</scp>‐proline)‐binding proteins from chick embryos are a profilin and a profilactin

1985 • 176 citations

Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets.

1992 • 175 citations

Profilin: At the crossroads of signal transduction and the actin cytoskeleton

1994 • 172 citations

Concentration and regulation of cyclic nucleotides, cyclic‐nucleotide‐dependent protein kinases and one of their major substrates in human platelets

1992 • 168 citations

Radixin is a novel member of the band 4.1 family.

1991 • 167 citations

The profilin multigene family of maize: differential expression of three isoforms

1993 • 162 citations

Purification of a vasodilator‐regulated phosphoprotein from human platelets

1989 • 160 citations

Profilin as a potential mediator of membrane-cytoskeleton communication

1993 • 159 citations

Distribution of profilin in fibroblasts correlates with the presence of highly dynamic actin filaments

1992 • 146 citations

Profilin-actin complexes directly elongate actin filaments at the barbed end

1992 • 141 citations

Vasodilator‐stimulated protein phosphorylation in platelets is mediated by cAMP‐ and cGMP‐dependent protein kinases

1987 • 132 citations

Identification and Characterization of a Novel Cytoskeleton-Associated pp60src Substrate

1991 • 113 citations

Mutagenesis of human profilin locates its poly(<scp>l</scp>‐prolme)‐bindmg site to a hydrophobic patch of aromatic amino acids

1993 • 108 citations

Role of Cyclic Nucleotide-Dependent Protein Kinases and Their Common Substrate VASP in the Regulation of Human Platelets

1993 • 104 citations

Identification of the poly-L-proline-binding site on human profilin.

1994 • 104 citations

Mutational analysis of yeast profilin.

1993 • 100 citations

Profilin, a weak CAP for actin and RAS

1991 • 89 citations

The wily ways of a parasite: induction of actin assembly by Listeria

1993 • 87 citations

The effect of divalent cations on the interaction between calf spleen profilin and different actins

1988 • 84 citations

Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteins.

1992 • 77 citations

Purification and characterization of two isoforms of Acanthamoeba profilin.

1986 • 72 citations

Interaction of Plant Profilin with Mammalian Actin

1994 • 71 citations

Endothelial cell-dependent phosphorylation of a platelet protein mediated by cAMP- and cGMP-elevating factors

1991 • 64 citations

Elucidation of the poly‐<scp>l</scp>‐proline binding site in Acanthamoeba profilin I by NMR spectroscopy

1994 • 61 citations

The profilin-actin complex: further characterization of profilin and studies on the stability of the complex

1983 • 56 citations

Cyclic nucleotide elevating vasodilators inhibit platelet aggregation at an early step of the activation cascade

1989 • 45 citations

Regulation of Platelet Function by the Cytoskeleton

1993 • 43 citations

The impact of molecular biology on models for cell adhesion

1994 • 41 citations

[9] Polyproline affinity method for purification of platelet profilin and modification with pyrene-maleimide

1991 • 39 citations

Mutational Analysis of Yeast Profilin

1993 • 37 citations

Mechanisms of Cytoskeletal Reorganization during Platelet Activation

1993 • 21 citations

Identification of a Human cDNA Encoding a Protein That Is Structurally and Functionally Related to the Yeast Adenylyl Cyclase-Associated CAP Proteins

1992 • 17 citations

Intracellular Motility: Profilin puts pathogens on the actin drive

1994 • 12 citations

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The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins. (1995) – The EMBO Journal | Metascience Observatory Explorer