cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

Rapid similarity searches of nucleic acid and protein data banks.

1983 • 1,577 citations

Base composition-independent hybridization in tetramethylammonium chloride: a method for oligonucleotide screening of highly complex gene libraries.

1985 • 818 citations

Autophosphorylation sites on the epidermal growth factor receptor

1984 • 730 citations

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

1987 • 670 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Tyr ⁵²⁷ Is Phosphorylated in pp60 ^{c- src} : Implications for Regulation

1986 • 567 citations

Enhanced graphic matrix analysis of nucleic acid and protein sequences.

1981 • 476 citations

Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity.

1988 • 458 citations

Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro.

1984 • 405 citations

Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo.

1988 • 404 citations

DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping

1974 • 395 citations

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1986 • 387 citations

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

1989 • 385 citations

Isolation of a calcium-dependent 35-kilodalton substrate for the epidermal growth factor receptor/kinase from A-431 cells.

1984 • 366 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

An 81 kd protein complexed with middle T antigen and pp60c-src: A possible phosphatidylinositol kinase

1987 • 346 citations

Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation.

1982 • 337 citations

Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells.

1983 • 294 citations

Transformation by Rous sarcoma virus: effects of src gene expression on the synthesis and phosphorylation of cellular polypeptides.

1979 • 293 citations

Regulation of the association of membrane skeletal protein 4.1 with glycophorin by a polyphosphoinositide

1985 • 288 citations

Purification of two spectrin-binding proteins: biochemical and electron microscopic evidence for site-specific reassociation between spectrin and bands 2.1 and 4.1.

1979 • 286 citations

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

1988 • 285 citations

Glycophorin is linked by band 4.1 protein to the human erythrocyte membrane skeleton

1984 • 283 citations

Interactions between protein 4.1 and band 3. An alternative binding site for an element of the membrane skeleton.

1985 • 274 citations

Amino-terminal sequence of p36 and associated p10: identification of the site of tyrosine phosphorylation and homology with S-100.

1985 • 268 citations

In vitro formation of a complex between cytoskeletal proteins of the human erythrocyte

1979 • 254 citations

Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

1985 • 243 citations

Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivo

1978 • 229 citations

Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus

1983 • 225 citations

Synthetic hexapeptide substrates and inhibitors of 3':5'-cyclic AMP-dependent protein kinase.

1976 • 206 citations

Molecular cloning of protein 4.1, a major structural element of the human erythrocyte membrane skeleton.

1986 • 205 citations

Synapsin I is a spectrin-binding protein immunologically related to erythrocyte protein 4.1

1985 • 202 citations

Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family.

1987 • 191 citations

A structural model of human erythrocyte protein 4.1.

1984 • 183 citations

The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.

1986 • 173 citations

Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.

1986 • 149 citations

Identification of the functional site of erythrocyte protein 4.1 involved in spectrin-actin associations.

1986 • 147 citations

Membrane skeletal protein 4.1 of avian erythrocytes is composed of multiple variants that exhibit tissue-specific expression

1984 • 136 citations

The 46,000-dalton tyrosine protein kinase substrate is widespread, whereas the 36,000-dalton substrate is only expressed at high levels in certain rodent tissues.

1984 • 103 citations

Microvillus-specific Mr 75,000 plasma membrane protein of human choriocarcinoma cells.

1987 • 80 citations

Human placental syncytiotrophoblastic Mr 75,000 polypeptide defined by antibodies to a synthetic peptide based on a cloned human endogenous retroviral DNA sequence.

1984 • 50 citations

[4] Purification of the intestnal microvillus cytoskeletal proteins villin, fimbrin, and ezrin

1986 • 36 citations

Epidermal growth factor receptor metabolism and protein kinase activity in human A431 cells infected with Snyder-Theilen feline sarcoma virus or harvey or Kirsten murine sarcoma virus

1983 • 35 citations

Immunofluorescent and immunochemical evidence for the expression of cytovillin in the microvilli of a wide range of cultured human cells

1988 • 32 citations

SUBSTRATE-SPECIFICITY OF A MULTIFUNCTIONAL CALMODULIN-DEPENDENT PROTEIN-KINASE

1985 • 20 citations