Regulation of Platelet Function by the Cytoskeleton

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

The platelet membrane glycoprotein IIb-IIIa complex

1988 • 1,031 citations

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

1985 • 968 citations

An interaction between alpha-actinin and the beta 1 integrin subunit in vitro.

1990 • 851 citations

The platelet membrane glycoprotein IIb-IIIa complex

1988 • 841 citations

Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change

1981 • 460 citations

Identification of membrane proteins mediating the interaction of human platelets

1980 • 383 citations

Molecular Defects in Interactions of Platelets with the Vessel Wall

1984 • 381 citations

Blood platelets express high levels of the pp60c-src-specific tyrosine kinase activity.

1986 • 329 citations

Thrombosis and haemostasis

1988 • 263 citations

Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins.

1990 • 237 citations

Identification of actin-binding protein as the protein linking the membrane skeleton to glycoproteins on platelet plasma membranes.

1985 • 236 citations

The cytoskeleton of the resting human blood platelet: structure of the membrane skeleton and its attachment to actin filaments.

1991 • 233 citations

Changes in the cytoskeletal structure of human platelets following thrombin activation.

1981 • 232 citations

Platelet tyrosine-specific protein phosphorylation is regulated by thrombin.

1988 • 229 citations

Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine.

1986 • 229 citations

Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets

1991 • 225 citations

Sur une nouvelle variete de dystrophie thrombocytaire-hemorragipare congenitale

1948 • 196 citations

Role of phosphorylation in mediating the association of myosin with the cytoskeletal structures of human platelets.

1982 • 195 citations

Interaction of pp60c-src, phospholipase C, inositol-lipid, and diacyglycerol kinases with the cytoskeletons of thrombin-stimulated platelets

1991 • 193 citations

Activated phosphoinositide 3-kinase associates with membrane skeleton in thrombin-exposed platelets.

1992 • 186 citations

The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering.

1987 • 186 citations

Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein Ib.

1985 • 173 citations

Reorganization of actin in platelets stimulated by thrombin as measured by the DNase I inhibition assay.

1979 • 169 citations

Role of the membrane skeleton in preventing the shedding of procoagulant-rich microvesicles from the platelet plasma membrane.

1990 • 162 citations

Identification of a membrane skeleton in platelets.

1988 • 161 citations

Evidence that activation of platelet calpain is induced as a consequence of binding of adhesive ligand to the integrin, glycoprotein IIb-IIIa.

1993 • 136 citations

Spectrin is associated with membrane-bound actin filaments in platelets and is hydrolyzed by the Ca2+-dependent protease during platelet activation

1987 • 123 citations

Isolation of a subpopulation of glycoprotein IIb-III from platelet membranes that is bound to membrane actin.

1985 • 55 citations

Centripetal myosin redistribution in thrombin-stimulated platelets

1984 • 44 citations

THE DISTRIBUTION OF GP lb AND THE STABILITY OF THE PLASMA MEMBRANE ARE DEPENDENT UPON AN INTACT MEMBRANE SKELETON

1987 • 1 citations