Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts

Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes.

1989 • 1,268 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site

1993 • 1,205 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

On the Crawling of Animal Cells

1993 • 1,020 citations

Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination

1987 • 984 citations

Cellular motions and thermal fluctuations: the Brownian ratchet

1993 • 874 citations

Fluorescent actin filaments move on myosin fixed to a glass surface.

1986 • 839 citations

L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein

1992 • 790 citations

Actin microfilament dynamics in locomoting cells

1991 • 789 citations

Antisense RNA Inactivation of Myosin Heavy Chain Gene Expression in Dictyostelium discoideum

1987 • 677 citations

Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells

1977 • 673 citations

Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.

1989 • 603 citations

Actin-Binding Protein Requirement for Cortical Stability and Efficient Locomotion

1992 • 567 citations

The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization

1992 • 533 citations

How profilin promotes actin filament assembly in the presence of thymosin β4

1993 • 532 citations

Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts

1990 • 444 citations

A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin.

1992 • 411 citations

Coordinate regulation of virulence genes in Listeria monocytogenes requires the product of the prfA gene

1992 • 404 citations

Nucleotide sequence of the lecithinase operon of Listeria monocytogenes and possible role of lecithinase in cell-to-cell spread

1992 • 393 citations

chickadee encodes a profilin required for intercellular cytoplasm transport during Drosophila oogenesis

1992 • 370 citations

Neuronal Cytomechanics: The Actin-Based Motility of Growth Cones

1988 • 331 citations

Listeria monocytogenes moves rapidly through the host-cell cytoplasm by inducing directional actin assembly.

1990 • 321 citations

Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation

1984 • 319 citations

Intracellular and cell-to-cell spread of Listeria monocytogenes involves interaction with F-actin in the enterocytelike cell line Caco-2

1990 • 301 citations

Control of actin polymerization in live and permeabilized fibroblasts.

1991 • 289 citations

The control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells.

1992 • 285 citations

Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells.

1990 • 264 citations

Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is autoregulated

1991 • 263 citations

Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cells.

1993 • 262 citations

Mechanism of the interaction of human platelet profilin with actin.

1991 • 235 citations

The role of actin in the temperature-dependent gelation and contraction of extracts of Acanthamoeba.

1976 • 216 citations

The contractile basis of amoeboid movement: V. The control of gelation, solation, and contraction in extracts from dictyostelium discoideum

1977 • 199 citations

Polarized distribution of Listeria monocytogenes surface protein ActA at the site of directional actin assembly

1993 • 196 citations

The Physics of Cell Motility

1987 • 190 citations

Poleward microtubule flux mitotic spindles assembled in vitro.

1991 • 184 citations

Actin from Thyone sperm assembles on only one end of an actin filament: a behavior regulated by profilin.

1983 • 180 citations

Poly(<scp>l</scp>‐proline)‐binding proteins from chick embryos are a profilin and a profilactin

1985 • 176 citations

Host cell actin assembly is necessary and likely to provide the propulsive force for intracellular movement of Listeria monocytogenes

1992 • 164 citations

Diacylglycerol-Stimulated Formation of Actin Nucleation Sites at Plasma Membranes

1992 • 147 citations

Distribution of profilin in fibroblasts correlates with the presence of highly dynamic actin filaments

1992 • 146 citations

Profilin-actin complexes directly elongate actin filaments at the barbed end

1992 • 141 citations

Actin filament nucleation by the bacterial pathogen, Listeria monocytogenes.

1990 • 134 citations

Cell locomotion: New research tests old ldeas on membrane and cytoskeletal flow

1991 • 133 citations

Targeted disruption of the ABP-120 gene leads to cells with altered motility.

1992 • 125 citations

Effects of profilin and profilactin on actin structure and function in living cells

1992 • 124 citations

Detection of listeriolysin, the thiol-dependent hemolysin in Listeria monocytogenes, Listeria ivanovii, and Listeria seeligeri

1989 • 123 citations

Dynamic actin structures stabilized byprofilin.

1994 • 122 citations

How Listeria exploits host cell actin to form its own cytoskeleton. II. Nucleation, actin filament polarity, filament assembly, and evidence for a pointed end capper.

1992 • 105 citations

Listeriosis

1989 • 103 citations

Characterization of renatured profilin purified by urea elution from poly‐L‐proline agarose columns

1989 • 93 citations

Localization of the ActA polypeptide of Listeria monocytogenes in infected tissue culture cell lines: ActA is not associated with actin "comets"

1993 • 91 citations

The nucleation-release model of actin filament dynamics in cell motility

1992 • 69 citations

Tetrahymena Profilin Is Localized in the Division Furrow

1992 • 48 citations

Induction of either contractile or structural actin-based gels in sea urchin egg cytoplasmic extract.

1980 • 40 citations