Woodchuck hepatitis virus infections: very rapid recovery after a prolonged viremia and infection of virtually every hepatocyte

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Apoptosis

1993 • 972 citations

A precursor—product relationship exists between oval cells and hepatocytes in rat liver

1987 • 448 citations

Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice.

1994 • 411 citations

Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene

1991 • 387 citations

Cyclin/PCNA immunostaining as an alternative to tritiated thymidine pulse labelling for marking S phase cells in paraffin sections from animal and human tissues

1989 • 295 citations

Replicative intermediates of hepatitis B virus in HepG2 cells that produce infectious virions

1988 • 272 citations

Transmission of Type B Viral Hepatitis to Chimpanzees

1973 • 227 citations

Rapid resolution of duck hepatitis B virus infections occurs after massive hepatocellular involvement

1992 • 188 citations

Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: Presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections

1989 • 147 citations

Tumor necrosis factor alpha negatively regulates hepatitis B virus gene expression in transgenic mice

1992 • 145 citations

Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways

1994 • 140 citations

Hepatic Stem Cell Compartment: Activation and Lineage Commitment

1993 • 104 citations

Cell Lineages in Hepatic Development and the Identification of Progenitor Cells in Normal and Injured Liver

1993 • 85 citations

Natural history of woodchuck hepatitis virus infections during the course of experimental viral infection: molecular virologic features of the liver and lymphoid tissues

1989 • 83 citations

Interleukin-2 downregulates hepatitis B virus gene expression in transgenic mice by a posttranscriptional mechanism

1993 • 75 citations

Models for Hepatic Progenitor Cell Activation

1993 • 68 citations

Suramin inhibitsin vitro infection by duck hepatitis B virus, rous sarcoma virus, and hepatitis delta virus

1988 • 67 citations

Core antigen and antibody in woodchucks after infection with woodchuck hepatitis virus

1984 • 65 citations

Characterization of the antiviral effects of 2' carbodeoxyguanosine in ducks chronically infected with duck hepatitis B virus.

1994 • 59 citations

Hepatitis B antigens in serum and liver of chimpanzees acutely infected with hepatitis B virus

1975 • 51 citations

Systemic distribution of woodchuck hepatitis virus in the tissues of experimentally infected woodchucks

1988 • 48 citations

In Vitro infection of woodchuck hepatocytes with woodchuck hepatitis virus and ground squirrel hepatitis virus

1989 • 47 citations

Ground Squirrel Hepatitis Virus Infection

2007 • 45 citations

Cellular and Molecular Mechanisms of Hepatocarcinogenesis Associated with Hepadnavirus Infection

1991 • 42 citations

Woodchuck Hepatitis Virus: Experimental Infection and Natural Occurrence

1984 • 36 citations

Laboratory assessment of hepatic injury in the woodchuck (Marmota monax).

1985 • 31 citations

Immunopathologic aspects of woodchuck hepatitis.

1984 • 29 citations

Immunofluorescence microscopy in experimentally induced, type B hepatitis in the chimpanzee

1978 • 25 citations

A technique for liver biopsy performed in Pekin ducks using anesthesia with Telazol.

1991 • 24 citations

Analysis of Hepadnavirus Gene Expression, Biology, and Pathogenesis in the Transgenic Mouse

1991 • 11 citations