Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

1985 • 1,052 citations

Liver regeneration: molecular mechanisms of growth control

1990 • 922 citations

Cell-Associated Plasminogen Activation: Regulation and Physiological Functions

1988 • 826 citations

Molecular Genetics of Inherited Variation in Human Color Vision

1986 • 777 citations

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1990 • 753 citations

TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1990 • 714 citations

Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

1989 • 692 citations

Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene

1987 • 479 citations

Transgenic Animals

1988 • 473 citations

A review of the molecular genetics of the human alpha-globin gene cluster

1989 • 443 citations

A review of the molecular genetics of the human alpha-globin gene cluster

1989 • 427 citations

Cell Polyploidy: Its Relation to Tissue Growth and Function

1977 • 394 citations

Differential regulation of metallothionein-thymidine kinase fusion genes in transgenic mice and their offspring

1982 • 379 citations

Transgenic Mice as Probes into Complex Systems

1989 • 368 citations

Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice.

1987 • 353 citations

Dwarf mice produced by genetic ablation of growth hormone-expressing cells.

1988 • 320 citations

Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice.

1989 • 318 citations

Is there a liver stem cell?

1990 • 304 citations

Duplication of seven exons in LDL receptor gene caused by Alu-Alu recombination in a subject with familial hypercholesterolemia

1987 • 293 citations

A Transgenic Mouse Model of the Chronic Hepatitis B Surface Antigen Carrier State

1985 • 281 citations

Oncogene-induced liver neoplasia in transgenic mice.

1989 • 249 citations

Histopathology Associated with Elevated Levels of Growth Hormone and Insulin-Like Growth Factor I in Transgenic Mice*

1989 • 229 citations

Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator

1990 • 223 citations

Germline mosaicism and Duchenne muscular dystrophy mutations

1987 • 199 citations

A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice.

1988 • 177 citations

Transmission distortion and mosaicism in an unusual transgenic mouse pedigree

1984 • 169 citations

Frequent deletions of the human X chromosome distal short arm result from recombination between low copy repetitive elements

1990 • 168 citations

Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes.

1988 • 161 citations

Peripheral neuropathies, hepatocellular carcinomas and islet cell adenomas in transgenic mice

1985 • 150 citations

Neonatal Hepatitis Induced by α ₁ -Antitrypsin: a Transgenic Mouse Model

1988 • 139 citations

Model for the incidence of embryonal cancers: application to retinoblastoma.

1978 • 134 citations

A partial deletion of the muscular dystrophy gene transmitted twice by an unaffected male

1987 • 123 citations

Homologous Recombination between Repeated Chromosomal Sequences in Mouse Cells

1984 • 114 citations

Infertility in Male Transgenic Mice: Disruption of Sperm Development by HSV-tk Expression in Postmeiotic Germ Cells1

1990 • 101 citations

Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene.

1989 • 97 citations

Analysis of the integrant in MyK-103 transgenic mice in which males fail to transmit the integrant.

1987 • 96 citations

Use of Gene Transfer to Increase Animal Growth

1985 • 96 citations

The Molecular Basis of Blood Diseases

1988 • 78 citations

Liver endothelium and not hepatocytes or Kupffer cells have transferrin receptors

1984 • 77 citations

Hot Spots for Growth Hormone Gene Deletions in Homologous Regions Outside of Alu Repeats

1990 • 77 citations

T antigen expression and tumorigenesis in transgenic mice containing a mouse major urinary protein/SV40 T antigen hybrid gene.

1989 • 77 citations

Somatic and germ-line reverse mutation rates of the retrovirus-induced dilute coat-color mutation of DBA mice.

1988 • 65 citations

Characterization of the cDNA coding for mouse plasminogen and localization of the gene to mouse chromosome 17

1990 • 54 citations

Analysis of the Integrant in MyK-103 Transgenic Mice in Which Males Fail to Transmit the Integrant

1987 • 36 citations

Germ-line intrachromosomal recombination restores fertility in transgenic MyK-103 male mice.

1991 • 33 citations