Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

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Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1994 • 1,472 citations

A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

1995 • 964 citations

nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine.

1990 • 859 citations

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.

1995 • 745 citations

Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies

1989 • 650 citations

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor

1993 • 569 citations

Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast

1995 • 561 citations

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

1990 • 507 citations

The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe

1988 • 493 citations

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases

1989 • 486 citations

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

1993 • 483 citations

The TPR snap helix: a novel protein repeat motif from mitosis to transcription

1991 • 452 citations

Cut2 proteolysis required for sister-chromatid separation in fission yeast

1996 • 451 citations

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

1993 • 422 citations

The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability.

1995 • 406 citations

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

1995 • 369 citations

Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle

1990 • 339 citations

The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1

1989 • 326 citations

Snap helix with knob and hole: Essential repeats in S. pombe nuclear protein nuc2 +

1990 • 306 citations

Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis

1986 • 292 citations

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis

1990 • 291 citations

Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.

1994 • 256 citations

Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts.

1991 • 246 citations

Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit

1993 • 244 citations

Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis.

1994 • 243 citations

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

1994 • 235 citations

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

1988 • 220 citations

Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis.

1988 • 210 citations

S. pombe gene sds22+ essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1

1991 • 191 citations

p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites.

1995 • 151 citations

A 13 kb resolution cosmid map of the 14 Mb fission yeast genome by nonrandom sequence-tagged site mapping

1993 • 150 citations

Mitotic regulation of protein phosphatases by the fission yeast sds22 protein

1993 • 129 citations

Phosphorylation of dis2 protein phosphatase at the C-terminal cdc2 consensus and its potential role in cell cycle regulation.

1994 • 119 citations

Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase.

1994 • 106 citations

The Saccharomyces cerevisiae Gene SDS22 Encodes a Potential Regulator of the Mitotic Function of Yeast Type 1 Protein Phosphatase

1995 • 94 citations

The Yeast CDC16 and CDC27 Genes Restrict DNA Replication to Once per Cell Cycle

1996 • 85 citations

Fission yeast TPR-family protein nuc2 is required for G1-arrest upon nitrogen starvation and is an inhibitor of septum formation

1995 • 60 citations

The EGP1 Gene May Be a Positive Regulator of Protein Phosphatase Type 1 in the Growth Control of Saccharomyces cerevisiae

1995 • 51 citations

Frontier questions about sister chromatid separation in anaphase

1995 • 49 citations

Molecular cloning of a human polypeptide related to yeast sds22, a regulator of protein phosphatase‐1

1995 • 43 citations

Cell Cycle: The only way out of mitosis

1995 • 31 citations

Sister-chromatid Separation and Protein Dephosphorylation in Mitosis

1991 • 27 citations

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