The Yeast CDC16 and CDC27 Genes Restrict DNA Replication to Once per Cell Cycle

Cyclin is degraded by the ubiquitin pathway

1991 • 2,355 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

1995 • 964 citations

An electrophoretic karyotype for yeast.

1985 • 787 citations

Mammalian Cell Fusion : Studies on the Regulation of DNA Synthesis and Mitosis

1970 • 759 citations

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

1994 • 759 citations

Macromolecule Synthesis in Temperature-sensitive Mutants of Yeast

1967 • 728 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor

1993 • 569 citations

Genes involved in sister chromatid separation are needed for b-type cyclin proteolysis in budding yeast

1995 • 561 citations

The Saccharomyces cerevisiae Cell Cycle

1981 • 539 citations

Chapter 19 Fluorescence Microscopy Methods for Yeast

1989 • 528 citations

A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

1990 • 507 citations

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

1993 • 483 citations

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a ‘reductional’ anaphase in the budding yeast Saccharomyces cerevisiae.

1995 • 402 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase.

1987 • 387 citations

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

1995 • 369 citations

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

1995 • 366 citations

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1995 • 357 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

Properties of Saccharomyces cerevisiae wee1 and its differential regulation of p34CDC28 in response to G1 and G2 cyclins.

1993 • 342 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

MPS1 and MPS2: novel yeast genes defining distinct steps of spindle pole body duplication.

1991 • 329 citations

A group of interacting yeast DNA replication genes.

1991 • 325 citations

Time of replication of yeast centromeres and telomeres

1988 • 295 citations

Isolation and characterization of Schizosaccharomyces pombe cut mutants that block nuclear division but not cytokinesis

1986 • 292 citations

p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast

1995 • 259 citations

Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis.

1994 • 243 citations

Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase cdc2.

1994 • 235 citations

Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.

1994 • 227 citations

A temperature-sensitive mutation of the Schizosaccharomyces pombe gene nuc2+ that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase.

1988 • 220 citations

Transposon-facilitated DNA sequencing.

1991 • 199 citations

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor

1993 • 198 citations

p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase

1995 • 190 citations

The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene

1990 • 151 citations

Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae.

1992 • 145 citations

The nuclear membrane prevents replication of human G2 nuclei but not G1 nuclei in Xenopus egg extract

1992 • 140 citations

The MCM2-3-5 proteins: are they replication licensing factors?

1994 • 124 citations

Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts.

1994 • 124 citations

Mammalian cell fusion

1974 • 112 citations

Requirement for ESP1 in the nuclear division of Saccharomyces cerevisiae.

1992 • 110 citations

The CDC20 Gene Product of Saccharomyces cerevisiae, a β-Transducin Homolog, Is Required for a Subset of Microtubule-Dependent Cellular Processes

1991 • 106 citations

Different G1 cyclins control the timing of cell cycle commitment in mother and daughter cells of the budding yeast S. cerevisiae

1992 • 101 citations

Origin activation and formation of single-strand TG1-3 tails occur sequentially in late S phase on a yeast linear plasmid.

1993 • 101 citations

Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor

1993 • 83 citations

bimA encodes a member of the tetratricopeptide repeat family of proteins and is required for the completion of mitosis in Aspergillus nidulans

1991 • 74 citations

Linking yeast genetics to mammalian genomes: identification and mapping of the human homolog of CDC27 via the expressed sequence tag (EST) data base.

1993 • 56 citations

The bimB3 mutation of Aspergillus nidulans uncouples DNA replication from the completion of mitosis.

1992 • 52 citations

The CDC20 gene product of Saccharomyces cerevisiae, a beta-transducin homolog, is required for a subset of microtubule-dependent cellular processes.

1991 • 46 citations

Continued DNA synthesis after a mitotic block in the double mutant cut1 cdc11 of the fission yeast Schizosaccharomyces Pombe

1990 • 23 citations

Characterization of temperature-sensitive mutants of yeast by a photomicrographic procedure

1973 • 15 citations