Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Tumor Suppressor Genes

1991 • 1,784 citations

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1988 • 1,699 citations

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.

1993 • 1,459 citations

ANIMAL CELL CYCLES AND THEIR CONTROL

1992 • 1,239 citations

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1992 • 1,031 citations

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

1989 • 848 citations

Cyclins and cancer

1991 • 701 citations

Protein phosphatases come of age

1989 • 616 citations

Regulation of Protein Serine-Threonine Phosphatase Type-2A by Tyrosine Phosphorylation

1992 • 598 citations

Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.

1988 • 595 citations

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases

1989 • 486 citations

An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues

1989 • 482 citations

Advances in second messenger and phosphoprotein research

1992 • 481 citations

Substrates for p34cdc2: In vivo veritas?

1990 • 472 citations

Function of a human cyclin gene as an oncogene.

1994 • 471 citations

Cyclins and cyclin-dependent kinases: take your partners

1993 • 441 citations

[37] Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1988 • 418 citations

Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.

1993 • 393 citations

Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle

1990 • 339 citations

The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1

1989 • 326 citations

Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.

1991 • 304 citations

The Structure, Role, and Regulation of Type 1 Protein Phosphatases

1992 • 295 citations

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis

1990 • 291 citations

Specific enzymatic dephosphorylation of the retinoblastoma protein.

1993 • 258 citations

Identification of Members of the Protein Phosphatase 1 Gene Family in the Rat and Enhanced Expression of Protein Phosphatase 1α Gene in Rat Hepatocellular Carcinomas

1990 • 227 citations

A new method for partial peptide mapping using N-chlorosuccinimide/urea and peptide silver staining in sodium dodecyl sulfate-polyacrylamide gels

1982 • 219 citations

Purification and characterization of Ca2+/calmodulin-dependent protein kinase I from bovine brain.

1987 • 212 citations

Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit.

1992 • 198 citations

p34cdc2: the S and M kinase?

1990 • 192 citations

A- and B-type cyclins differentially modulate substrate specificity of cyclin-cdk complexes.

1993 • 190 citations

Involvement of a type 1 protein phosphatase encoded by bws1+ in fission yeast mitotic control

1989 • 188 citations

Tumor suppressor genes

1993 • 147 citations

Cell culture for biochemists

1991 • 138 citations

Isolation and sequence analysis of a cDNA clone encoding a type‐1 protein phosphatase catalytic subunit: Homology with protein phosphatase 2A

1987 • 128 citations

Cell cycle oscillation of phosphatase inhibitor-2 in rat fibroblasts coincident with p34cdc2 restriction

1990 • 120 citations

Two isoforms of protein phosphatase 1 may be produced from the same gene

1988 • 108 citations

Specific Enzymatic Dephosphorylation of the Retinoblastoma Protein

1993 • 96 citations

Drosophila contains three genes that encode distinct isoforms of protein phosphatase 1

1990 • 92 citations

Protein (serine and threonine) phosphate phosphatases

1984 • 92 citations

Proline-directed protein phosphorylation and cell cycle regulation

1991 • 72 citations

The retinoblastoma protein and cell cycle regulation

1992 • 71 citations

Characterization of the cytoplasmic proline-directed protein kinase in proliferative cells and tissues as a heterodimer comprised of p34cdc2 and p58cyclin A.

1991 • 63 citations

Expression of multiple type 1 phosphoprotein phosphatases in Arabidopsis thaliana

1993 • 59 citations

Multiple roles for protein phosphatase 1 in regulating the Xenopus early embryonic cell cycle.

1992 • 57 citations

Renaturation of protein phosphatase 1 expressed at high levels in insect cells using a baculovirus vector

1990 • 50 citations

Two potentially oncogenic cyclins, cyclin A and cyclin D1, share common properties of subunit configuration, tyrosine phosphorylation and physical association with the Rb protein.

1993 • 49 citations

Phosphorylation and inactivation of protein phosphatase 1 by pp60v-src.

1986 • 47 citations

Co-purification of p34cdc2/p58cyclin A proline-directed protein kinase and the retinoblastoma tumor susceptibility gene product: interaction of an oncogenic serine/threonine protein kinase with a tumor-suppressor protein.

1992 • 31 citations

G1 expression and multistage dynamics of cyclin A in human osteosarcoma cells.

1993 • 30 citations

Three forms of phosphatase type 1 in Swiss 3T3 fibroblasts. Free catalytic subunit appears to mediate s6 dephosphorylation.

1990 • 27 citations

Activation of type‐1 protein phosphatase by cdc2 kinase

1992 • 19 citations