Renal Fibrosis

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

An Overview of Epithelio-Mesenchymal Transformation

1995 • 1,505 citations

Pathophysiology of Progressive Nephropathies

1998 • 1,250 citations

Identification and characterization of a fibroblast marker: FSP1.

1995 • 1,050 citations

Structure and biological activity of basement membrane proteins

1989 • 967 citations

Tubulointerstitial Changes as a Major Determinant in the Progression of Renal Damage

1992 • 951 citations

A Network Model for the Organization of Type IV Collagen Molecules in Basement Membranes

1981 • 889 citations

Macromolecular organization of basement membranes

1996 • 661 citations

Molecular insights into renal interstitial fibrosis.

1996 • 636 citations

Type IV collagen: structure, gene organization, and role in human diseases. Molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis.

1993 • 610 citations

Basement Membrane Proteins: Structure, Assembly, and Cellular Interactions

1992 • 584 citations

Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in vitro

1999 • 476 citations

Early role of Fsp1 in epithelial-mesenchymal transformation

1997 • 433 citations

Transformations between epithelium and mesenchyme: Normal, pathological, and experimentally induced

1995 • 428 citations

Anti-angiogenic cues from vascular basement membrane collagen.

2000 • 412 citations

Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats

1998 • 402 citations

Renal basement membrane components

1999 • 347 citations

Basement membrane structure in situ: evidence for lateral associations in the type IV collagen network.

1987 • 342 citations

Basal lamina assembly

1994 • 322 citations

Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis.

1988 • 311 citations

New Functions for Non-collagenous Domains of Human Collagen Type IV

2000 • 308 citations

Matrix Attachment Regulates FAS-Induced Apoptosis in Endothelial Cells

2001 • 284 citations

Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule

1992 • 264 citations

Identification of the Anti-angiogenic Site within Vascular Basement Membrane-derived Tumstatin

2001 • 226 citations

Transforming growth factor beta enhances integrin expression and type IV collagenase secretion in human monocytes.

1993 • 211 citations

Type IV Collagen of the Glomerular Basement Membrane

2000 • 206 citations

Hypoxia stimulates proximal tubular cell matrix production via a TGF-β1-independent mechanism

1997 • 198 citations

Abnormal Compartmentalization of Cartilage Matrix Components in Mice Lacking Collagen X: Implications for Function

1997 • 197 citations

Renal pathology of human immunodeficiency virus infection.

1998 • 165 citations

Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-β1-dependent mechanism in vitro

2001 • 150 citations

The role of tubulointerstitial injury in chronic renal failure

2000 • 147 citations

Update of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis

2004 • 124 citations

Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines

1992 • 114 citations

The arrangement of intra‐ and intermolecular disulfide bonds in the carboxyterminal, non‐collagenous aggregation and cross‐linking domain of basement‐membrane type IV collagen

1988 • 106 citations

Therapy with antisense TGF-β1 oligodeoxynucleotides reduces kidney weight and matrix mRNAs in diabetic mice

2000 • 105 citations

Type I collagen gel induces Madin-Darby canine kidney cells to become fusiform in shape and lose apical-basal polarity.

1989 • 100 citations

Expression of β1 integrins changes during transformation of avian lens epithelium to mesenchyme in collagen gels

1994 • 99 citations

Shape and assembly of type IV procollagen obtained from cell culture.

1982 • 92 citations

Type IV collagen lateral associations in the EHS tumor matrix. Comparison with amniotic and in vitro networks.

1988 • 88 citations

Glomerular basement membrane. Identification of dimeric subunits of the noncollagenous domain (hexamer) of collagen IV and the Goodpasture antigen

1991 • 80 citations

Role of extracellular matrix, growth factors and proto-oncogenes in metanephric development

1997 • 80 citations

Transdifferentiation: a new angle on renal fibrosis.

1996 • 78 citations

Assembly of Basement Membranes^a

1990 • 68 citations

Comparative analysis of the noncollagenous NC1 domain of type IV collagen: Identification of structural features important for assembly, function, and pathogenesis

1998 • 66 citations

Epithelial-mesenchymal transitions in development and tumor progression

1995 • 66 citations

Assembly of Type IV Collagen

2000 • 65 citations

Transdifferentiation comes of age

2000 • 64 citations

On the Progression of Chronic Renal Disease

1995 • 62 citations

Constitutive Synthesis of a 92-kDa Keratinocyte-Derived Type IV Collagenase Is Enhanced by Type I Collagen and Decreased by Type IV Collagen Matrices

1992 • 61 citations

The importance of tubulointerstitial damage in progressive renal disease

2000 • 57 citations

Structure and Biology of the Globular Domain of Basement Membrane Type IV Collagena

1985 • 56 citations

Aberrant Signal Peptide Cleavage of Collagen X in Schmid Metaphyseal Chondrodysplasia

2001 • 53 citations

Identification of a multifunctional, cell-binding peptide sequence from the a1(NC1) of type IV collagen.

1990 • 50 citations

Epithelial—mesenchymal transformation of renal tubular epithelial cells in vitro and in vivo

2000 • 47 citations

Assembly of the exogenous extracellular matrix during basement membrane formation by alveolar epithelial cells in vitro

2000 • 47 citations

Relevance of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis

1998 • 41 citations

Angiotensin II Induces α3(IV) Collagen Expression in Cultured Murine Proximal Tubular Cells

1999 • 36 citations

Tubulointerstitial nephritis antigen: An extracellular matrix protein that selectively regulates tubulogenesis vs. glomerulogenesis during mammalian renal development

1999 • 35 citations

Phenotypic features of cortical interstitial cells potentially important in fibrosis.

1996 • 31 citations

Interaction of Collagen α1(X) Containing Engineered NC1 Mutations with Normal α1(X) in Vitro

1999 • 31 citations

Transforming growth factor-β1 regulates basement membrane formation by alveolar epithelial cells in vitro

1999 • 25 citations

Anoikis

2000 • 25 citations

THE DEVELOPMENT OF SERUM-FREE HORMONE-SUPPLEMENTED MEDIA FOR PRIMARY KIDNEY CULTURES AND THEIR USE IN EXAMINING RENAL FUNCTIONS

1981 • 20 citations

Cloning of rat 92‐kDa type IV collagenase and expression of an active recombinant catalytic domain

1996 • 19 citations

Structure and composition of type IV collagen of bovine aorta

1993 • 18 citations

Pathology of progressive nephropathies

2000 • 15 citations

Culture on basement membrane does not reverse the phenotype of lens derived mesenchyme-like cells.

1989 • 15 citations

Transforming growth factor-beta modulation of the alpha 1(IV) collagen gene in murine proximal tubular cells

1996 • 14 citations

Isolation and characterisation of a chicken gelatinase (type IV collagenase)

1991 • 10 citations

Differential expression of collagen type IV alpha-chains in the tubulointerstitial compartment in experimental chronic serum sickness nephritis

1999 • 9 citations

Characterization of the Collagen Phenotype of Rabbit Proximal Tubule Cells in Culture

1999 • 8 citations

The Evolving Contribution of Renal Pathology to Understanding Interstitial Nephritis

1998 • 2 citations