Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Transforming growth factor beta

2011 • 1,990 citations

Negative regulation of transforming growth factor-β by the proteoglycan decorin

1990 • 1,490 citations

Structural-functional relationships in diabetic nephropathy.

1984 • 1,202 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

Nonenzymatic Glycosylation and the Pathogenesis of Diabetic Complications

1984 • 1,012 citations

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1990 • 1,002 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

Transforming Growth Factor‐β

1990 • 696 citations

TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains

1990 • 612 citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

1988 • 604 citations

Distribution and modulation of the cellular receptor for transforming growth factor-beta.

1987 • 556 citations

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.

1990 • 555 citations

Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice.

1989 • 451 citations

Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans.

1988 • 418 citations

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.

1990 • 397 citations

Absence of TGF-β Receptors and Growth Inhibitory Responses in Retinoblastoma Cells

1988 • 331 citations

Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis.

1988 • 311 citations

Transforming Growth Factor β

1988 • 295 citations

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability.

1985 • 292 citations

Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1

1992 • 248 citations

Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells.

1989 • 235 citations

High glucose induces cell hypertrophy and stimulates collagen gene transcription in proximal tubule

1990 • 196 citations

ELEVATED EXPRESSION OF TRANSFORMING GROWTH FACTOR BETA AND PROTEOGLYCAN PRODUCTION IN EXPERIMENTAL GLOMERULONEPHRITIS

1990 • 196 citations

Structure and Function of the Kidney in Diabetic Glomerulosclerosis

1980 • 186 citations

The renal tubulointerstitium in diabetes mellitus

1991 • 169 citations

Renal hypertrophy in experimental diabetes mellitus

1983 • 164 citations

Connective tissue in diabetes mellitus: biochemical alterations of the intercellular matrix with special reference to proteoglycans, collagens and basement membranes.

1985 • 127 citations

Transforming growth factor-beta production in anti-glomerular basement membrane disease in the rabbit.

1991 • 123 citations

Regulation of mesangial cell growth by polypeptide mitogens. Inhibitory role of transforming growth factor beta.

1989 • 122 citations

BSC-1 growth inhibitor transforms a mitogenic stimulus into a hypertrophic stimulus for renal proximal tubular cells: relationship to Na+/H+ antiport activity.

1985 • 94 citations

Effects of transforming growth factor-beta, transforming growth factor-alpha, and other growth factors on renal proximal tubule cells.

1991 • 88 citations

Isolation and characterization of the nephritogenic antigen producing anti-tubular basement membrane disease.

1985 • 84 citations

Effects of Polyol-Pathway Inhibition and Dietary myo-Inositol on Glomerular Hemodynamic Function in Experimental Diabetes Mellitus in Rats

1991 • 76 citations

The influence of glucose concentration on angiotensin II-induced hypertrophy of proximal tubular cells in culture

1991 • 72 citations

Expression of transforming growth factor-β1 and β2 in rat glomeruli

1990 • 71 citations

Immunodetection and modulation of cellular growth with antibodies against native transforming growth factor-beta 1.

1987 • 68 citations

Effect of myo-inositol on cell proliferation and collagen transcription and secretion in proximal tubule cells cultured in elevated glucose.

1991 • 57 citations

Autocrine and Paracrine Regulation of Kidney Epithelial Cell Growth

1989 • 46 citations

The growth inhibitor of African green monkey (BSC-1) cells is transforming growth factors .beta.1 and .beta.2

1989 • 19 citations

The effect of transforming growth factor-beta on mouse mesangial cell proliferation.

1989 • 11 citations

Effect of transforming growth factor-beta on extracellular matrix production by cultured rat mesangial cells.

1993 • 4 citations

Autocrine And Paracrine Regulation Of Kidney Epithelial Cell Growth

1989 • 1 citations