Structure and biological activity of basement membrane proteins

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Laminin–a glycoprotein from basement membranes.

1979 • 2,372 citations

Cell Biology of Extracellular Matrix

1988 • 1,498 citations

Basement membrane complexes with biological activity

1986 • 1,489 citations

FIBRONECTIN AND ITS RECEPTORS

1988 • 1,336 citations

Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma

1982 • 1,225 citations

Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures.

1988 • 1,209 citations

Osteonectin, a bone-specific protein linking mineral to collagen

1981 • 1,131 citations

Laminin and Other Basement Membrane Components

1987 • 900 citations

A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane.

1988 • 892 citations

A Network Model for the Organization of Type IV Collagen Molecules in Basement Membranes

1981 • 889 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding

1987 • 677 citations

Isolation of a heparan sulfate-containing proteoglycan from basement membrane.

1980 • 672 citations

Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix

1981 • 666 citations

Role of laminin in the attachment of PAM 212 (epithelial) cells to basement membrane collagen

1980 • 661 citations

The basement membrane in pathology.

1983 • 660 citations

Structure and Function of Collagen Types

1987 • 653 citations

The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival.

1984 • 634 citations

A murine tumor producing a matrix of basement membrane.

1977 • 602 citations

YIGSR, a Synthetic Laminin Pentapeptide, Inhibits Experimental Metastasis Formation

1987 • 555 citations

Type VII collagen is a major structural component of anchoring fibrils.

1986 • 545 citations

Normal and abnormal aspects of proteinuria

1986 • 536 citations

Structure and Biosynthesis of Basement Membranes

1973 • 519 citations

Role of laminin a chain in the development of epithelial cell polarity

1988 • 488 citations

Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.

1988 • 486 citations

Biological activities of laminin

1985 • 470 citations

Entactin, a novel basal lamina-associated sulfated glycoprotein.

1981 • 454 citations

Laminin-nidogen complex. Extraction with chelating agents and structural characterization

1987 • 453 citations

Identification of the Goodpasture antigen as the alpha 3(IV) chain of collagen IV.

1988 • 451 citations

A pentapeptide from the laminin B1 chain mediates cell adhesion and binds to 67000 laminin receptor

1987 • 431 citations

Laminin receptor on human breast carcinoma cells.

1983 • 419 citations

Mapping by monoclonal antibody detection of glycosaminoglycans in connective tissues

1984 • 387 citations

Type VII collagen forms an extended network of anchoring fibrils.

1987 • 383 citations

In vivo and in vitro observations on laminin production by Schwann cells.

1983 • 382 citations

Sequence of the cDNA encoding the laminin B1 chain reveals a multidomain protein containing cysteine-rich repeats.

1987 • 381 citations

Merosin, a protein specific for basement membranes of Schwann cells, striated muscle, and trophoblast, is expressed late in nerve and muscle development.

1988 • 371 citations

Self-assembly of basement membrane collagen

1984 • 347 citations

Basement membrane structure in situ: evidence for lateral associations in the type IV collagen network.

1987 • 342 citations

Domains of laminin with growth-factor activity

1989 • 341 citations

Epidermolysis bullosa acquisita antigen is the globular carboxyl terminus of type VII procollagen.

1988 • 340 citations

Mapping of domains in human laminin using monoclonal antibodies: localization of the neurite-promoting site.

1986 • 318 citations

Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell ‘culture shock’ glycoprotein of Mr 43,000.

1986 • 315 citations

Protease Resistance and Conformation of Laminin

1982 • 313 citations

The Human Laminin Receptor Is a Member of the Integrin Family of Cell Adhesion Receptors

1988 • 310 citations

The laminin B2 chain has a multidomain structure homologous to the B1 chain.

1987 • 307 citations

Structure and function of epidermal growth factor‐like regions in proteins

1988 • 305 citations

7‐S Collagen: Characterization of an Unusual Basement Membrane Structure

1980 • 304 citations

In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization.

1987 • 292 citations

Basement membrane glycoprotein laminin binds to heparin

1980 • 286 citations

Localization of the Goodpasture epitope to a novel chain of basement membrane collagen.

1987 • 277 citations

Nidogen: a new, self‐aggregating basement membrane protein

1983 • 275 citations

Expression of nidogen and laminin in basement membranes during mouse embryogenesis and in teratocarcinoma cells

1985 • 272 citations

Localization of flexible sites in thread-like molecules from electron micrographs

1984 • 269 citations

Laminin polymerization in vitro. Evidence for a two-step assembly with domain specificity.

1985 • 264 citations

Subunits of laminin are differentially synthesized in mouse eggs and early embryos

1983 • 263 citations

Altered levels of laminin receptor mRNA in various human carcinoma cells that have different abilities to bind laminin.

1986 • 261 citations

Components of Torpedo electric organ and muscle that cause aggregation of acetylcholine receptors on cultured muscle cells.

1984 • 251 citations

Embryonic neural retinal cell response to extracellular matrix proteins: developmental changes and effects of the cell substratum attachment antibody (CSAT).

1987 • 249 citations

Purification and characterization of a murine basement membrane collagen-degrading enzyme secreted by metastatic tumor cells.

1983 • 245 citations

The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sites.

1987 • 243 citations

Partial characterization of newly synthesized proteoglycans isolated from the glomerular basement membrane.

1981 • 239 citations

Amino acid sequence of mouse nidogen, a multidomain basement membrane protein with binding activity for laminin, collagen IV and cells.

1989 • 230 citations

The participation of a putative cell surface receptor for laminin and fibronectin in peripheral neurite extension

1986 • 223 citations

Studies on the Biosynthesis of Laminin by Murine Parietal Endoderm Cells

1981 • 222 citations

Localization of binding sites for laminin, heparan sulfate proteoglycan and fibronectin on basement membrane (type IV) collagen

1986 • 216 citations

Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth.

1987 • 216 citations

Structure and interactions of heparan sulfate proteoglycans from a mouse tumor basement membrane

1984 • 214 citations

Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissues

1987 • 211 citations

Isolation and characterization of native adult osteonectin.

1985 • 207 citations

Isolation of two forms of basement membrane proteoglycans.

1985 • 202 citations

Interactions of basement membrane components

1983 • 200 citations

Attachment of cells to basement membrane collagen type IV.

1986 • 198 citations

Binding of laminin to type IV collagen: a morphological study.

1985 • 196 citations

Evidence for coiled-coil alpha-helical regions in the long arm of laminin.

1985 • 195 citations

Two distinct cell-binding domains in laminin can independently promote nonneuronal cell adhesion and spreading [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546]

1987 • 195 citations

cDNA clones coding for the pro-alpha1(IV) chain of human type IV procollagen reveal an unusual homology of amino acid sequences in two halves of the carboxyl-terminal domain.

1985 • 194 citations

Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a serine proteinase inhibitor (ovomucoid).

1988 • 189 citations

Synthesis of type IV collagen and laminin in cultures of skeletal muscle cells and their assembly on the surface of myotubes

1982 • 188 citations

Laminin increases the release of type IV collagenase from malignant cells.

1986 • 188 citations

Laminin molecular domains which alter metastasis in a murine model.

1984 • 187 citations

Laminin receptors for neurite formation.

1988 • 187 citations

Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.

1982 • 182 citations

Increased mRNA expression of a laminin-binding protein in human colon carcinoma: complete sequence of a full-length cDNA encoding the protein.

1988 • 179 citations

Characterization of the procollagen IV cleavage products produced by a specific tumor collagenase.

1984 • 178 citations

Developmental and transformation-sensitive expression of the Sparc gene on mouse chromosome 11.

1986 • 175 citations

Subunit structure and assembly of the globular domain of basement-membrane collagen type IV

1984 • 174 citations

The genes for the alpha 1(IV) and alpha 2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure.

1988 • 171 citations

Circulating antibodies to mouse laminin in Chagas disease, American cutaneous leishmaniasis, and normal individuals recognize terminal galactosyl(alpha 1-3)-galactose epitopes.

1987 • 170 citations

Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.

1984 • 169 citations

Electron microscopy and other physical methods for the characterization of extracellular matrix components: Laminin, fibronectin, collagen IV, collagen VI, and proteoglycans

1987 • 168 citations

Physical and immunochemical studies of the globular domain of type IV collagen. Cryptic properties of the Goodpasture antigen.

1985 • 168 citations

Structure of low density heparan sulfate proteoglycan isolated from a mouse tumor basement membrane

1987 • 167 citations

Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen.

1988 • 167 citations

Amino acid sequence of the non‐collagenous globular domain (NC1) of the α1 (IV) chain of basement membrane collagen as derived from complementary DNA

1985 • 164 citations

Human laminin B1 chain. A multidomain protein with gene (LAMB1) locus in the q22 region of chromosome 7.

1987 • 162 citations

Cranin: a laminin-binding protein of cell membranes.

1987 • 161 citations

Characterization of protease-resistant fragments of laminin mediating attachment and spreading of rat hepatocytes.

1983 • 161 citations

Genes for basement membrane proteins are coordinately expressed in differentiating F9 cells but not in normal adult murine tissues

1987 • 159 citations

Laminin binds specifically to sulfated glycolipids.

1985 • 158 citations

Properties of the globular domain of type IV collagen and its relationship to the Goodpasture antigen.

1985 • 157 citations

Purification and tissue distribution of a small protein (BM-40) extracted from a basement membrane tumor

1986 • 157 citations

Structural requirements for the stimulation of neurite outgrowth by two variants of laminin and their inhibition by antibodies.

1988 • 155 citations

Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan.

1988 • 153 citations

Isolation and characterization of rat schwannoma neurite-promoting factor: evidence that the factor contains laminin

1985 • 152 citations

Basement Membrane Proteins: Molecular Structure and Function

1988 • 150 citations

Laminin and its receptor

1985 • 149 citations

Human platelets contain and secrete osteonectin, a major protein of mineralized bone.

1986 • 148 citations

A novel synthetic peptide from the B1 chain of laminin with heparin-binding and cell adhesion-promoting activities.

1988 • 147 citations

Drosophila substrate adhesion molecule: Sequence of laminin B1 chain reveals domains of homology with mouse

1988 • 145 citations

Structures of the asparagine-linked sugar chains of laminin

1986 • 142 citations

Identification and interaction repertoire of large forms of the basement membrane protein nidogen.

1985 • 139 citations

Human laminin B2 chain. Comparison of the complete amino acid sequence with the B1 chain reveals variability in sequence homology between different structural domains.

1988 • 134 citations

High resolution immunoelectron microscopic localization of functional domains of laminin, nidogen, and heparan sulfate proteoglycan in epithelial basement membrane of mouse cornea reveals different topological orientations.

1988 • 132 citations

The Glomerular Basement Membrane

1981 • 131 citations

Structure and affinity for antithrombin of heparan sulfate chains derived from basement membrane proteoglycans.

1987 • 129 citations

Solubilization of protein BM‐40 from a basement membrane tumor with cheating agents and evidence for its identity with osteonectin and SPARC

1987 • 128 citations

The role of Ca2+ binding in the self-aggregation of laminin-nidogen complexes.

1988 • 128 citations

Identification of the precursor protein to basement membrane heparan sulfate proteoglycans.

1985 • 124 citations

Completion of the amino acid sequence of the α1 chain of human basement membrane collagen (type IV) reveals 21 non‐triplet interruptions located within the collagenous domain

1987 • 124 citations

Immunological characterization of basement membrane types of heparan sulfate proteoglycan.

1985 • 124 citations

Structure of human‐basement‐membrane (type IV) collagen

1984 • 121 citations

Chemical structure of the lipopolysaccharide of Haemophilus influenzae strain I‐69 Rd⁻/b⁺

1988 • 119 citations

Structure and distribution of N-linked oligosaccharide chains on various domains of mouse tumour laminin

1988 • 119 citations

Drosophila laminin: characterization and localization.

1987 • 118 citations

Drosophila basement membrane procollagen alpha 1(IV). II. Complete cDNA sequence, genomic structure, and general implications for supramolecular assemblies.

1988 • 116 citations

The biosynthesis, processing, and secretion of laminin by human choriocarcinoma cells.

1985 • 115 citations

Peptide inhibitors of fibronectin, laminin, and other adhesion molecules: Unique and shared features

1987 • 114 citations

Synthesis of laminin and entactin by F9 cells induced with retinoic acid and dibutyryl cyclic AMP.

1983 • 113 citations

Complete primary structure of the α₁‐chain of human basement membrane (type IV) collagen

1987 • 112 citations

Characterization of heparan sulfate-proteoglycan of glomerular basement membranes.

1984 • 112 citations

Osteontctin mRNA: distribution in normal and transformed cells

1986 • 110 citations

Regulation of cell attachment and cell number by fibronectin and laminin

1986 • 108 citations

The arrangement of intra‐ and intermolecular disulfide bonds in the carboxyterminal, non‐collagenous aggregation and cross‐linking domain of basement‐membrane type IV collagen

1988 • 106 citations

Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.

1987 • 105 citations

Characterization of proteolytic fragments of the laminin‐nidogen complex and their activity in ligand‐binding assays

1988 • 104 citations

Immunogold quantitation of laminin, type IV collagen, and heparan sulfate proteoglycan in a variety of basement membranes.

1988 • 104 citations

Localization of three distinct heparin-binding domains of laminin by monoclonal antibodies.

1988 • 104 citations

Purification and structural characterization of intact and fragmented nidogen obtained from a tumor basement membrane

1986 • 104 citations

Glomerular basement membrane proteoglycans are derived from a large precursor.

1988 • 103 citations

Self-assembly of a high molecular weight basement membrane heparan sulfate proteoglycan into dimers and oligomers.

1987 • 101 citations

Human basement membrane collagen (type IV)

1988 • 100 citations

Isolation and characterization of the heparan sulfate proteoglycan of the bovine glomerular basement membrane.

1984 • 100 citations

Focal Adhesions and Cell-Matrix Interactions

1988 • 99 citations

Folding of collagen IV

1988 • 98 citations

Distribution of a 69-kD laminin-binding protein in aortic and microvascular endothelial cells: modulation during cell attachment, spreading, and migration.

1988 • 94 citations

Basement membrane (type IV) collagen is a heteropolymer.

1982 • 93 citations

Monoclonal antibodies to the human laminin receptor recognize structurally distinct sites

1985 • 89 citations

The role of the main noncollagenous domain (NC1) in type IV collagen self-assembly.

1986 • 89 citations

Laminin increases both levels and activity of tyrosine hydroxylase in calf adrenal chromaffin cells.

1986 • 87 citations

Drosophila basement membrane procollagen IV. I. Protein characterization and distribution.

1988 • 87 citations

The high‐affinity binding of laminin to cells

1989 • 83 citations

Structural study of long arm fragments of laminin

1988 • 82 citations

Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region.

1988 • 82 citations

Construction of a model for the aggregation and cross-linking region (7S domain) of type IV collagen based upon an evaluation of the primary structure of the alpha1 and alpha2 chains in this region

1987 • 80 citations

Restricted homology between human alpha 1 type IV and other procollagen chains.

1985 • 78 citations

Procollagen IV. Association to tetramers.

1983 • 78 citations

Identification of asparagine-linked oligosaccharides involved in tumor cell adhesion to laminin and type IV collagen.

1984 • 77 citations

Domain structure of the basement membrane heparan sulfate proteoglycan

1987 • 77 citations

Anchoring fibrils contain the carboxyl-terminal globular domain of type VII procollagen, but lack the amino-terminal globular domain.

1987 • 76 citations

Cloning and complete amino acid sequences of human and murine basement membrane protein BM‐40 (SPARC, osteonectin)

1988 • 76 citations

Attachment to an endogenous laminin-like protein initiates sprouting by leech neurons.

1988 • 73 citations

Laminin is structurally conserved in the sea urchin basal lamina

1987 • 72 citations

Nature of sulphated macromolecules in mouse Reichert's membrane. Evidence for tyrosine O-sulphate in basement-membrane proteins

1985 • 72 citations

Basement membranes

1987 • 71 citations

Type IV collagen from chicken muscular tissues. Isolation and characterization of the pepsin-resistant fragments

1980 • 71 citations

Characterization of 64-, 123- and 182-base-pair exons in the mouse α2(IV) collagen gene

1985 • 71 citations

Inhibition of laminin self-assembly and interaction with type IV collagen by antibodies to the terminal domain of the long arm.

1986 • 70 citations

Structure of mouse type IV collagen. Amino-acid sequence of the C-terminal 511-residue-long triple-helical segment of the alpha2(IV) chain and its comparison with the alpha1(IV) chain

1986 • 70 citations

Extensive homology between the carboxyl-terminal peptides of mouse alpha 1(IV) and alpha 2(IV) collagen.

1987 • 70 citations

The neurite-promoting domain of human laminin promotes attachment and induces characteristic morphology in non-neuronal cells

1988 • 65 citations

Post-translational assembly and glycosylation of laminin subunits in parietal endoderm-like F9 cells

1985 • 65 citations

Steady-state levels of mRNAs coding for the type IV collagen and laminin polypeptide chains of basement membranes exhibit marked tissue-specific stoichiometric variations in the rat.

1987 • 63 citations

Multiple forms of heparan sulfate proteoglycans in the Engelbreth-Holm-Swarm mouse tumor. The occurrence of high density forms bearing both heparan sulfate and chondroitin sulfate side chains.

1987 • 61 citations

Characterization of the promoter for the alpha 1 (IV) collagen gene. DNA sequences within the first intron enhance transcription.

1988 • 61 citations

Amino acid sequence of the N-terminal aggregation and cross-linking region (7S domain) of the alpha1 (IV) chain of human basement membrane collagen

1985 • 60 citations

Covalent Structure of Mouse Type‐IV Collagen

1982 • 57 citations

Amino acid sequence and distribution of mRNA encoding a major skeletal muscle laminin binding protein: an extracellular matrix-associated protein with an unusual COOH-terminal polyaspartate domain.

1988 • 53 citations

cDNA clones completing the nucleotide and derived amino acid sequence of the alpha 1 chain of basement membrane (type IV) collagen from mouse

1988 • 52 citations

Synthetic pentapeptide from the B1 chain of laminin promotes B16F10 melanoma cell migration

1988 • 51 citations

Noncollagenous Proteins of Basement Membranes

1987 • 47 citations

Isolation and characterization of a laminin-binding protein from rat and chick muscle.

1988 • 46 citations

Human von Willebrand factor: The molecular glue of platelet plugs

1988 • 45 citations

Isolation of the osteonectin gene: evidence that a variable region of the osteonectin molecule is encoded within one exon

1988 • 43 citations

Alpha 1 type IV collagen gene evolved differently from fibrillar collagen genes.

1986 • 42 citations

Alternative model for the internal structure of laminin

1985 • 41 citations

The laminin B2 chain promoter contains unique repeat sequences and is active in transient transfection.

1988 • 40 citations

Reductive cleavage and reformation of the interchain and intrachain disulfide bonds in the globular hexameric domain NC1 involved in network assembly of basement membrane collagen (type IV)

1988 • 39 citations

Large introns in the 3' end of the gene for the pro alpha 1 (IV) chain of human basement membrane collagen.

1986 • 39 citations

Primary structure of the mouse laminin B2 chain and comparison with laminin B1

1988 • 38 citations

Extensive structural differences between genes for the α₁ and α₂ chains of type IV collagen despite conservation of coding sequences

1987 • 36 citations

Control of laminin synthesis during differentiation of F9 embryonal carcinoma cells

1986 • 36 citations

Structural analysis of three subunits of laminin from teratocarcinoma-derived parietal endoderm cells

1983 • 36 citations

The N terminus of laminin A chain is homologous to the B chains

1988 • 35 citations

Analysis of degradation of the basement membrane protein nidogen, using a specific monoclonal antibody

1988 • 35 citations

Type VII Collagen

1987 • 35 citations

Binding of Ca²⁺ influences susceptibility of laminin to proteolytic digestion and interactions between domain‐specific laminin fragments

1988 • 35 citations

cDNA and protein sequence of the NC1 domain of the α₂‐chain of collagen IV and its comparison with α₁(IV)

1986 • 33 citations

Partial structure of the human ?2(IV) collagen chain and chromosomal localization of the gene (COL4A2)

1987 • 31 citations

Separation and characterization of two polypeptide chains from the 7S cross-linking domain of basement-membrane (type IV) collagen

1984 • 30 citations

Nucleotide sequence coding for the human type IV collagen α₂ chain cDNA reveals extensive homology with the NC‐1 domain of α₁ (IV) but not with the collagenous domain or 3untranslated region

1987 • 28 citations

Carboxyl-terminal sequence of entactin deduced from a cDNA clone.

1987 • 25 citations

Proposed alignment of helical interruptions in the two subunits of the basement membrane (type IV) collagen

1986 • 24 citations

cDNA cloning, expression and mapping of human laminin B2 gene to chromosome 1q31

1988 • 24 citations

Basement membrane heparan sulfate proteoglycan from the L2 rat yolk sac carcinoma

1984 • 24 citations

The gene for the alpha 1(IV) chain of human type IV procollagen: the exon structures do not coincide with the two structural subdomains in the globular carboxy-terminus of the protein.

1986 • 19 citations

Biosynthesis and supramolecular assembly of procollagen IV in neonatal lung.

1986 • 12 citations

Deleted Work

1955 • 0 citations