CpG oligodeoxynucleotides enhance the capacity of adenovirus-mediated CD154 gene transfer to generate effective B-cell lymphoma vaccines.

CpG motifs in bacterial DNA trigger direct B-cell activation

1995 • 3,543 citations

Isolation of a Common Receptor for Coxsackie B Viruses and Adenoviruses 2 and 5

1997 • 3,081 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

CpG Motifs in Bacterial DNA and Their Immune Effects

2002 • 2,520 citations

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

1998 • 2,378 citations

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

1993 • 2,182 citations

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1998 • 2,106 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

1998 • 809 citations

Interleukin-12: A Cytokine at the Interface of Inflammation and Immunity

1998 • 785 citations

Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells

2000 • 604 citations

Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

1997 • 526 citations

Functions of CD40 on B cells, dendritic cells and other cells

1997 • 490 citations

Antitumor Activity of Deoxyribonucleic Acid Fraction From <italic>Mycobacterium bovis</italic> BCG. I. Isolation, Physicochemical Characterization, and Antitumor Activity<xref ref-type="fn" rid="FN2">2</xref>

1984 • 471 citations

CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia

2000 • 345 citations

Immunogenicity of Apoptotic Cells In Vivo: Role of Antigen Load, Antigen-Presenting Cells, and Cytokines

1999 • 295 citations

Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery

1995 • 292 citations

Immunostimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism

2000 • 263 citations

Immunostimulatory DNA: Sequence‐dependent production of potentially harmful or useful cytokines

1997 • 248 citations

Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells.

1998 • 247 citations

Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells

1996 • 237 citations

Immunostimulatory CpG-oligonucleotides cause proliferation, cytokine production, and an immunogenic phenotype in chronic lymphocytic leukemia B cells

2000 • 216 citations

Immunostimulatory Oligodeoxynucleotides Containing CpG Motifs Enhance the Efficacy of Monoclonal Antibody Therapy of Lymphoma

1997 • 208 citations

Acquired CD40-ligand deficiency in chronic lymphocytic leukemia

1997 • 206 citations

Integrin αvβ1 Is an Adenovirus Coreceptor

2001 • 198 citations

Purification of a Type 5 Recombinant Adenovirus Encoding Human p53 by Column Chromatography

1995 • 185 citations

Analytical Anion-Exchange HPLC of Recombinant Type-5 Adenoviral Particles

1997 • 182 citations

Prospects for CD40-directed experimental therapy of human cancer

2002 • 168 citations

DNA activates human immune cells through a CpG sequence‐dependent manner

1999 • 156 citations

CD40 Ligand Induces an Antileukemia Immune Response In Vivo

1997 • 142 citations

CpG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens

2001 • 137 citations

Antigen-presenting cells that phagocytose apoptotic tumor-derived cells are potent tumor vaccines.

1999 • 133 citations

Tumor immunotherapy: the tumor cell as an antigen-presenting cell

1994 • 132 citations

Enhancement of antigen-presenting cell surface molecules involved in cognate interactions by immunostimulatory DNA sequences

1999 • 112 citations

CpG oligonucleotides enhance the tumor antigen-specific immune response of a granulocyte macrophage colony-stimulating factor-based vaccine strategy in neuroblastoma.

2003 • 107 citations

Adenovirus vector infection of chronic lymphocytic leukemia B cells

1996 • 91 citations

Anti-Tumor Immunity Induced by in Vivo Adenovirus Vector-Mediated Expression of CD40 Ligand in Tumor Cells

1999 • 91 citations

An improved anion-exchange HPLC method for the detection and purification of adenoviral particles

2000 • 91 citations

Antitumor Effect of CD40 Ligand: Elicitation of Local and Systemic Antitumor Responses by IL-12 and B7

1998 • 90 citations

Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients

2001 • 80 citations

Antitumor Activity of the DNA Fraction from <italic>Mycobacterium bovis</italic> BCG. II. Effects on Various Syngeneic Mouse Tumors<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1985 • 79 citations

Tumor regression induced by intratumor administration of adenovirus vector expressing CD40 ligand and naive dendritic cells.

2000 • 65 citations

Antimetastatic effect of CpG DNA mediated by type I IFN.

2001 • 64 citations

BCG (Bacillus of Calmette Guerin) therapy of high-risk superficial bladder cancer

2002 • 57 citations

In vivo antitumor effect of CD40L-transduced tumor cells as a vaccine for B-cell lymphoma.

2002 • 45 citations

POTENT ANTITUMOR EFFECTS OF CD154 TRANSDUCED TUMOR CELLS IN EXPERIMENTAL BLADDER CANCER

2001 • 42 citations

Antitumor activity of the DNA fraction from Mycobacterium bovis BCG. II

1985 • 28 citations

CD40-expressing carcinoma cells induce down-regulation of CD40 ligand (CD154) and impair T-cell functions.

2002 • 22 citations

T cell activation following infection of primary follicle center lymphoma B cells with adenovirus encoding CD154

2001 • 21 citations