IL-17-Mediated Regulation of Innate and Acquired Immune Response against Pulmonary Mycobacterium bovis Bacille Calmette-Guérin Infection

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

2003 • 2,856 citations

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

2000 • 2,755 citations

Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17

2003 • 1,828 citations

Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

2003 • 1,652 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense

2001 • 1,505 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice

2003 • 1,280 citations

A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

2002 • 1,238 citations

Antigen-Specific T Cell Sensitization Is Impaired in IL-17-Deficient Mice, Causing Suppression of Allergic Cellular and Humoral Responses

2002 • 1,063 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses

1996 • 991 citations

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

1998 • 954 citations

IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

2001 • 928 citations

Neutrophil Recruitment by Human IL-17 Via C-X-C Chemokine Release in the Airways

1999 • 881 citations

Requirement of Interleukin‐17A for Systemic Anti–Candida albicansHost Defense in Mice

2004 • 840 citations

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

1998 • 810 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Airway remodeling-associated mediators in moderate to severe asthma: Effect of steroids on TGF-β, IL-11, IL-17, and type I and type III collagen expression

2003 • 626 citations

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

2005 • 598 citations

Microbial Lipopeptides Induce the Production of IL-17 in Th Cells

2000 • 589 citations

High Levels of IL-17 in Rheumatoid Arthritis Patients: IL-15 Triggers In Vitro IL-17 Production Via Cyclosporin A-Sensitive Mechanism

2000 • 588 citations

IL-17, Produced by Lymphocytes and Neutrophils, Is Necessary for Lipopolysaccharide-Induced Airway Neutrophilia: IL-15 as a Possible Trigger

2003 • 538 citations

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

1993 • 528 citations

Tuberculosis: Latency and Reactivation

2001 • 495 citations

IL-23 Compensates for the Absence of IL-12p70 and Is Essential for the IL-17 Response during Tuberculosis but Is Dispensable for Protection and Antigen-Specific IFN-γ Responses if IL-12p70 Is Available

2005 • 459 citations

Cutting Edge: Roles of Toll-Like Receptor 4 and IL-23 in IL-17 Expression in Response toKlebsiella pneumoniaeInfection

2003 • 452 citations

Enhancing Effect of IL-17 on IL-1-Induced IL-6 and Leukemia Inhibitory Factor Production by Rheumatoid Arthritis Synoviocytes and Its Regulation by Th2 Cytokines

1998 • 451 citations

Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection

2003 • 402 citations

IL-17 Stimulates Granulopoiesis in Mice: Use of an Alternate, Novel Gene Therapy-Derived Method for In Vivo Evaluation of Cytokines

1998 • 320 citations

IL-17 Stimulates Intraperitoneal Neutrophil Infiltration Through the Release of GROα Chemokine from Mesothelial Cells

2000 • 304 citations

Mice Lacking Bioactive IL-12 Can Generate Protective, Antigen-Specific Cellular Responses to Mycobacterial Infection Only if the IL-12 p40 Subunit Is Present

2002 • 300 citations

Evidence for a Role of IL-17 in Organ Allograft Rejection: IL-17 Promotes the Functional Differentiation of Dendritic Cell Progenitors

1999 • 297 citations

Ubiquitous Transgenic Expression of the IL-23 Subunit p19 Induces Multiorgan Inflammation, Runting, Infertility, and Premature Death

2001 • 293 citations

Neutrophils Play a Protective Nonphagocytic Role in SystemicMycobacterium tuberculosisInfection of Mice

2000 • 268 citations

Requirement of Endogenous Stem Cell Factor and Granulocyte-Colony-Stimulating Factor for IL-17-Mediated Granulopoiesis

2000 • 266 citations

Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3‐signaling chemokines

2003 • 233 citations

A Protective and Agonistic Function of IL-12p40 in Mycobacterial Infection

2001 • 226 citations

IL-23 Enhances the Inflammatory Cell Response in Cryptococcus neoformans Infection and Induces a Cytokine Pattern Distinct from IL-12

2006 • 222 citations

Increased granulopoiesis through interleukin-17 and granulocyte colony-stimulating factor in leukocyte adhesion molecule–deficient mice

2001 • 192 citations

Retracted: Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection

2002 • 170 citations

Tumor Necrosis Factor Alpha Stimulates Killing ofMycobacterium tuberculosisby Human Neutrophils

2002 • 154 citations

EXPRESSION OF IL-17 IN HUMAN MEMORY CD45RO+T LYMPHOCYTES AND ITS REGULATION BY PROTEIN KINASE A PATHWAY

1999 • 144 citations

Mouse IL-17: A Cytokine Preferentially Expressed by αβTCR+CD4—CD8— T Cells

1996 • 138 citations

A role of GM-CSF in the accumulation of neutrophils in the airways caused by IL-17 and TNF‐α

2003 • 132 citations

Rapid Neutrophil Response Controls Fast‐Replicating Intracellular Bacteria but Not Slow‐ReplicatingMycobacterium tuberculosis

2000 • 130 citations

Killing of Mycobacterium tuberculosis by Neutrophils: A Nonoxidative Process

1990 • 129 citations

Capacity of Human Neutrophils to Kill Mycobacterium tuberculosis

1987 • 115 citations

Expression of Chemokines and Induction of Rapid Cell Death in Human Blood Neutrophils by Mycobacterium tuberculosis

1998 • 99 citations

Neutrophil-Mediated Mycobacteriocidal Immunity in the Lung duringMycobacterium bovisBCG Infection in C57BL/6 Mice

2002 • 97 citations

Accumulation of γδ T Cells in the Lungs and Their Regulatory Roles in Th1 Response and Host Defense against Pulmonary Infection with Cryptococcus neoformans

2004 • 92 citations

Interleukin-17 and its receptor.

1997 • 83 citations

Neutrophils fromMycobacterium avium-Infected Mice Produce TNF-α, IL-12, and IL-1β and Have a Putative Role in Early Host Response

1999 • 82 citations

T Lymphocytic and Immature Macrophage Alveolitis in Active Pulmonary Tuberculosis

1996 • 64 citations

Stimulation of Neutrophil Granulocytes withMycobacterium bovisBacillus Calmette-Guérin Induces Changes in Phenotype and Gene Expression and Inhibits Spontaneous Apoptosis

2003 • 60 citations

Rapid Accumulation of Eosinophils in Lung Lesions in Guinea Pigs Infected with Mycobacterium tuberculosis

2004 • 60 citations

Involvement of IL-17 in Fas ligand-induced inflammation

2004 • 56 citations

Interleukin-1 alpha stimulates KC synthesis in rat mesangial cells: glucocorticoids inhibit KC induction by IL-1

1994 • 31 citations

A 14-yr-old male with dyspnoea, productive cough and chest pain

2003 • 29 citations

T cell regulation of the chronic peritoneal neutrophilia during mycobacterial infections

1992 • 23 citations

Fas Ligand Induces Cell-Autonomous IL-23 Production in Dendritic Cells, a Mechanism for Fas Ligand-Induced IL-17 Production

2005 • 21 citations