Involvement of IL-17 in Fas ligand-induced inflammation

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

1999 • 1,660 citations

Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense

2001 • 1,505 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Antigen-Specific T Cell Sensitization Is Impaired in IL-17-Deficient Mice, Causing Suppression of Allergic Cellular and Humoral Responses

2002 • 1,063 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages.

1998 • 954 citations

Fas and Fas ligand: lpr and gld mutations

1995 • 906 citations

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand.

1996 • 894 citations

Neutrophil Recruitment by Human IL-17 Via C-X-C Chemokine Release in the Airways

1999 • 881 citations

Interleukin-17 promotes angiogenesis and tumor growth

2002 • 795 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene.

1993 • 751 citations

Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion

1998 • 604 citations

High Levels of IL-17 in Rheumatoid Arthritis Patients: IL-15 Triggers In Vitro IL-17 Production Via Cyclosporin A-Sensitive Mechanism

2000 • 588 citations

IL-17, Produced by Lymphocytes and Neutrophils, Is Necessary for Lipopolysaccharide-Induced Airway Neutrophilia: IL-15 as a Possible Trigger

2003 • 538 citations

Essential roles of the Fas ligand in the development of hepatitis

1997 • 483 citations

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

1997 • 453 citations

The intriguing role of polymorphonuclear neutrophils in antitumor reactions

2001 • 411 citations

Regulation of the Proinflammatory Effects of Fas Ligand (CD95L)

1998 • 391 citations

Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

1998 • 377 citations

Transgenic expression of CD95 ligand on islet β cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts

1997 • 373 citations

Interleukin-17 inhibits tumor cell growth by means of a T-cell–dependent mechanism

2002 • 348 citations

Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis

1999 • 344 citations

Antitumor effect of locally produced CD95 ligand

1997 • 315 citations

IL-17 Stimulates Intraperitoneal Neutrophil Infiltration Through the Release of GROα Chemokine from Mesothelial Cells

2000 • 304 citations

A Role for IL-18 in Neutrophil Activation

2001 • 293 citations

Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice.

1999 • 291 citations

Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen.

1995 • 248 citations

Caspase-1-Independent, Fas/Fas Ligand–Mediated IL-18 Secretion from Macrophages Causes Acute Liver Injury in Mice

1999 • 245 citations

Interleukin-17

1998 • 201 citations

Differential Antitumor Effects of Administration of Recombinant IL-18 or Recombinant IL-12 Are Mediated Primarily by Fas-Fas Ligand- and Perforin-Induced Tumor Apoptosis, Respectively

1999 • 199 citations

Chemotactic activity of soluble Fas ligand against phagocytes.

1998 • 159 citations

A major role for the Fas pathway in acute graft-versus-host disease.

1996 • 158 citations

Fas Ligand Engagement of Resident Peritoneal Macrophages In Vivo Induces Apoptosis and the Production of Neutrophil Chemotactic Factors

2001 • 146 citations

Increased elastase and myeloperoxidase activity associated with neutrophil recruitment by IL-17 in airways in vivo

2000 • 139 citations

Mouse IL-17: A Cytokine Preferentially Expressed by αβTCR+CD4—CD8— T Cells

1996 • 138 citations

Cutting Edge: Chemotactic Activity of Soluble Fas Ligand Against Phagocytes

1998 • 123 citations

Differential target cell sensitivity to CTL-activated death pathways in hepatitis B virus transgenic mice.

1997 • 98 citations

Proinflammatory consequences of transgenic Fas ligand expression in the heart

2000 • 88 citations

The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity

2001 • 86 citations

Fas/Apo-1 activates nuclear factor kappa B and induces interleukin-6 production.

1995 • 77 citations

Fas-Mediated Stimulation Induces IL-8 Secretion by Rheumatoid Arthritis Synoviocytes Independently of CPP32-Mediated Apoptosis

1996 • 65 citations

Regulation of Fas Ligand-Induced Apoptosis by TNF

2001 • 64 citations

Therapeutic effect of an anti-Fas ligand mAb on lethal graft-versus-host disease

1999 • 62 citations

Interleukin-1 alpha stimulates KC synthesis in rat mesangial cells: glucocorticoids inhibit KC induction by IL-1

1994 • 31 citations

Participation of a dominant cytotoxic T cell population defined by a monoclonal antibody in syngeneic anti‐tumor responses

1990 • 11 citations