Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice

ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS

1996 • 2,527 citations

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

2002 • 1,644 citations

Autoimmunity to type II collagen an experimental model of arthritis.

1977 • 1,599 citations

Antigen-Specific T Cell Sensitization Is Impaired in IL-17-Deficient Mice, Causing Suppression of Allergic Cellular and Humoral Responses

2002 • 1,063 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1996 • 985 citations

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

1999 • 723 citations

IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis.

1996 • 642 citations

Microbial Lipopeptides Induce the Production of IL-17 in Th Cells

2000 • 589 citations

IL-17: prototype member of an emerging cytokine family

2002 • 589 citations

High Levels of IL-17 in Rheumatoid Arthritis Patients: IL-15 Triggers In Vitro IL-17 Production Via Cyclosporin A-Sensitive Mechanism

2000 • 588 citations

Interferon‐γ confers resistance to experimental allergic encephalomyelitis

1996 • 478 citations

Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice.

1997 • 465 citations

Failure to Suppress the Expansion of the Activated Cd4 T Cell Population in Interferon γ–Deficient Mice Leads to Exacerbation of Experimental Autoimmune Encephalomyelitis

2000 • 424 citations

IL-17 Is Produced by Some Proinflammatory Th1/Th0 Cells But Not by Th2 Cells

1999 • 415 citations

IL-1-Independent Role of IL-17 in Synovial Inflammation and Joint Destruction During Collagen-Induced Arthritis

2001 • 396 citations

High susceptibility to collagen-induced arthritis in mice lacking IFN-gamma receptors.

1997 • 361 citations

The need for IgG2c specific antiserum when isotyping antibodies from C57BL/6 and NOD mice

1998 • 325 citations

Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity.

1988 • 264 citations

Protection from Collagen-Induced Arthritis in Granulocyte-Macrophage Colony-Stimulating Factor-Deficient Mice

1998 • 233 citations

CD4+ Th1 and CD8+ Type 1 Cytotoxic T Cells Both Play a Crucial Role in the Full Development of Contact Hypersensitivity

2000 • 229 citations

Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritis

2000 • 214 citations

Could HLA-DRB1 be the protective locus in rheumatoid arthritis?

1995 • 178 citations

Severe inflammatory arthritis and lymphadenopathy in the absence of TNF

2001 • 147 citations

Enhanced autoimmune arthritis in IFN-gamma receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells.

1999 • 98 citations

Suppression of autoimmune arthritis in interleukin‐1‐deficient mice in which T cell activation is impaired due to low levels of CD40 ligand and OX40 expression on T cells

2002 • 87 citations

Enhanced Autoimmune Arthritis in IFN-γ Receptor-Deficient Mice Is Conditioned by Mycobacteria in Freund’s Adjuvant and by Increased Expansion of Mac-1+ Myeloid Cells

1999 • 79 citations

IL-1-induced tumor necrosis factor-alpha elicits inflammatory cell infiltration in the skin by inducing IFN-gamma-inducible protein 10 in the elicitation phase of the contact hypersensitivity response

2003 • 67 citations

Type II collagen-induced murine arthritis

1990 • 61 citations

Characterization of monoclonal antibody specific for human type II collagen: possible implication in collagen-induced arthritis.

1985 • 34 citations