Mitochondrial Import of Subunit Va of Cytochrome c Oxidase Characterized with Yeast Mutants

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria.

1982 • 1,152 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles

1974 • 949 citations

Mitochondrial protein import

1989 • 820 citations

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins

1990 • 756 citations

A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers.

1986 • 493 citations

Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism

1992 • 422 citations

Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences.

1991 • 372 citations

MOM19, an import receptor for mitochondrial precursor proteins

1989 • 334 citations

Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria

1991 • 278 citations

Successive translocation into and out of the mitochondrial matrix: Targeting of proteins to the intermembrane space by a bipartite signal peptide

1987 • 275 citations

A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins.

1993 • 274 citations

Transport of proteins into mitochondria: a potassium diffusion potential is able to drive the import of ADP/ATP carrier.

1985 • 245 citations

Functional cooperation of mitochondrial protein import receptors in yeast.

1993 • 227 citations

Import of ADP/ATP carrier into mitochondria: two receptors act in parallel.

1990 • 201 citations

Targeting proteins into mitochondria

1986 • 171 citations

Sequences from a prokaryotic genome or the mouse dihydrofolate reductase gene can restore the import of a truncated precursor protein into yeast mitochondria.

1987 • 160 citations

Presequence and mature part of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix.

1993 • 158 citations

Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae.

1991 • 145 citations

Role of cytochrome c heme lyase in the import of cytochrome c into mitochondria.

1988 • 140 citations

Mitochondrial protein import

1989 • 131 citations

Targeting of the Master Receptor MOM19 to Mitochondria

1991 • 124 citations

Deletion of the receptor MOM19 strongly impairs import of cleavable preproteins into Saccharomyces cerevisiae mitochondria.

1994 • 124 citations

The protein import machine of the mitochondrial inner membrane

1994 • 121 citations

Import of cytochrome b₂ to the mitochondrial intermembrane space: The tightly folded heme‐binding domain makes import dependent upon matrix ATP

1993 • 116 citations

Chapter 16 Analysis of Mitochondrial Protein Import Using Translocation Intermediates and Specific Antibodies

1991 • 115 citations

A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria

1994 • 114 citations

The essential yeast protein MIM44 (encoded by MPI1) is involved in an early step of preprotein translocation across the mitochondrial inner membrane.

1993 • 113 citations

The requirement of matrix ATP for the import of precursor proteins into the mitochondrial matrix and intermembrane space

1994 • 107 citations

Yeast mitochondria lacking the two import receptors Mas20p and Mas70p can efficiently and specifically import precursor proteins.

1994 • 86 citations

Preproteins of chloroplast envelope inner membrane contain targeting information for receptor-dependent import into fungal mitochondria.

1994 • 67 citations

The protein import receptor MOM19 of yeast mitochondria

1993 • 61 citations

Protein import into mitochondria and peroxisomes

1990 • 53 citations

An unusual mitochondrial import pathway for the precursor to yeast cytochrome c oxidase subunit Va.

1991 • 49 citations

Intramitochondrial sorting of the precursor to yeast cytochrome c oxidase subunit Va.

1993 • 37 citations

Removal of a hydrophobic domain within the mature portion of a mitochondrial inner membrane protein causes its mislocalization to the matrix.

1990 • 33 citations

Bilayer‐penetrating properties enable apocytochrome c to follow a special import pathway into mitochondria

1992 • 24 citations