Development and Homeostasis of T Cell Memory in Rhesus Macaque

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

Changes in thymic function with age and during the treatment of HIV infection

1998 • 1,887 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

1997 • 1,124 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

Skewed maturation of memory HIV-specific CD8 T lymphocytes

2001 • 1,025 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

Turnover of naive- and memory-phenotype T cells.

1994 • 900 citations

Dynamics of T Lymphocyte Responses: Intermediates, Effectors, and Memory Cells

2000 • 807 citations

Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation

1998 • 722 citations

Lifespan of human lymphocyte subsets defined by CD45 isoforms

1992 • 642 citations

Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry

1995 • 561 citations

Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency.

1997 • 560 citations

11-color, 13-parameter flow cytometry: Identification of human naive T cells by phenotype, function, and T-cell receptor diversity

2001 • 452 citations

Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule.

1990 • 447 citations

Population Biology of Lymphocytes: The Flight for Survival

2000 • 439 citations

Control of lymphocyte recirculation in man. II. Differential regulation of the cutaneous lymphocyte-associated antigen, a tissue-selective homing receptor for skin-homing T cells.

1993 • 393 citations

Rapid Turnover of T Lymphocytes in SIV-Infected Rhesus Macaques

1998 • 375 citations

Use of overlapping peptide mixtures as antigens for cytokine flow cytometry

2001 • 358 citations

Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selectin on T cells during the virgin to memory cell transition.

1993 • 349 citations

Differential expression of homing-associated adhesion molecules by T cell subsets in man.

1990 • 270 citations

Regulation of CD27 expression on subsets of mature T-lymphocytes.

1993 • 247 citations

Identification of a human recent thymic emigrant phenotype

2000 • 243 citations

Dynamics of CCR5 Expression by CD4⁺T Cells in Lymphoid Tissues during Simian Immunodeficiency Virus Infection

2000 • 241 citations

Factors influencing T-cell turnover in HIV-1–seropositive patients

2000 • 236 citations

Flow cytometric assessment of human T-cell differentiation in thymus and bone marrow

1992 • 224 citations

Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+CD28– cytotoxic effector clones

1999 • 211 citations

Normal Human CD4+ Memory T Cells Display Broad Heterogeneity in Their Activation Threshold for Cytokine Synthesis

1998 • 202 citations

Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4 ⁺ and CD8 ⁺ T cell turnover in HIV-infected patients

2000 • 199 citations

Differential expression of lymphocyte homing receptors by human memory/effector T cells in pulmonary versus cutaneous immune effector sites

1994 • 192 citations

Flow cytometric assessment of human T-cell differentiation in thymus and bone marrow

1992 • 183 citations

Memory T Cells Constitute a Subset of the Human CD8+CD45RA+ Pool with Distinct Phenotypic and Migratory Characteristics

2001 • 174 citations

Clonality and Longevity of CD4+CD28null T Cells Are Associated with Defects in Apoptotic Pathways

2000 • 173 citations

Human Virus-Specific CD8+ CTL Clones Revert from CD45ROhigh to CD45RAhigh In Vivo: CD45RAhighCD8+ T Cells Comprise Both Naive and Memory Cells

1999 • 173 citations

Altered representation of naive and memory CD8 T cell subsets in HIV-infected children.

1995 • 160 citations

Postthymic Development of CD28−CD8+ T Cell Subset: Age-Associated Expansion and Shift from Memory to Naive Phenotype

1999 • 156 citations

Distribution of human CMV-specific memory T cells among the CD8pos. subsets defined by CD57, CD27, and CD45 isoforms

1999 • 152 citations

Loss of CD28 expression on CD8+ T cells is induced by IL-2 receptor γ chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis

2000 • 141 citations

Human CD28−CD8+ T Cells Contain Greatly Expanded Functional Virus-Specific Memory CTL Clones

1999 • 137 citations

Immune Reconstitution after 2 Years of Successful Potent Antiretroviral Therapy in Previously Untreated Human Immunodeficiency Virus Type 1–Infected Adults

1999 • 114 citations

Characterization of Gut-Associated Lymphoid Tissue (GALT) of Normal Rhesus Macaques

1997 • 108 citations

Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy

1999 • 107 citations

Changes in the Composition of Circulating CD8⁺T Cell Subsets during Acute Epstein‐Barr and Human Immunodeficiency Virus Infections in Humans

2000 • 105 citations

Increased rates of CD4⁺and CD8⁺T lymphocyte turnover in simian immunodeficiency virus-infected macaques

1998 • 104 citations

Comparative Analysis of Cytotoxic T Lymphocytes in Lymph Nodes and Peripheral Blood of Simian Immunodeficiency Virus-Infected Rhesus Monkeys

1999 • 81 citations

Independent regulation of cutaneous lymphocyte-associated antigen expression and cytokine synthesis phenotype during human CD4+ memory T cell differentiation.

1997 • 73 citations

Differential Dynamics of CD4⁺and CD8⁺T-Lymphocyte Proliferation and Activation in Acute Simian Immunodeficiency Virus Infection

2000 • 69 citations

Naive CD4+ lymphocytes convert to anergic or memory-like cells in T cell-deprived recipients

2001 • 67 citations

CD45 isoform phenotypes of human T cells: CD4+CD45RA–RO+ memory T cells re-acquire CD45RA without losing CD45RO

1999 • 64 citations

Soluble and Cellular Markers of T Cell Activation in Patients with Pulmonary Sarcoidosis

1993 • 59 citations

Peripheral human CD8+CD28+T lymphocytes give rise to CD28–progeny, but IL-4 prevents loss of CD28 expression

1999 • 53 citations

Characterization of lymphocyte subsets in rhesus macaques during the first year of life

2000 • 47 citations

The Effects of Prolonged Administration of 5-Bromodeoxyuridine on Cells of the Immune System

2000 • 29 citations

Immune reconstitution with donor-derived memory/effector T cells after orthotopic liver transplantation.

1997 • 29 citations

Expression of the T-cell activation antigens CD27 and CD28 in normal and psoriatic skin

1996 • 25 citations

Expression of the T-cell activation antigens CD27 and CD28 in normal and psoriatic skin

1996 • 19 citations