Dynamics of CCR5 Expression by CD4⁺T Cells in Lymphoid Tissues during Simian Immunodeficiency Virus Infection

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes

1998 • 1,574 citations

Gastrointestinal Tract as a Major Site of CD4 ⁺ T Cell Depletion and Viral Replication in SIV Infection

1998 • 1,408 citations

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

1995 • 951 citations

Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4 ⁺ T Cells

1999 • 868 citations

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression

1997 • 642 citations

Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages

1999 • 577 citations

Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.

1985 • 545 citations

Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.

1990 • 443 citations

Induction of HIV-1 Replication in Latently Infected CD4+ T Cells Using a Combination of Cytokines

1998 • 356 citations

Distinct Pathogenic Sequela in Rhesus Macaques Infected with CCR5 or CXCR4 Utilizing SHIVs

1999 • 323 citations

Identifying the Target Cell in Primary Simian Immunodeficiency Virus (SIV) Infection: Highly Activated Memory CD4⁺T Cells Are Rapidly Eliminated in Early SIV Infection In Vivo

2000 • 252 citations

Rapid Infection of Oral Mucosal-Associated Lymphoid Tissue with Simian Immunodeficiency Virus

1999 • 243 citations

Both Memory and CD45RA⁺/CD62L⁺Naive CD4⁺T Cells Are Infected in Human Immunodeficiency Virus Type 1-Infected Individuals

1999 • 217 citations

Immunopathogenesis of HIV infection

1991 • 213 citations

Gastrointestinal T Lymphocytes Retain High Potential for Cytokine Responses but Have Severe CD4⁺T-Cell Depletion at All Stages of Simian Immunodeficiency Virus Infection Compared to Peripheral Lymphocytes

1998 • 200 citations

Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men.

1990 • 198 citations

Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro.

1997 • 187 citations

CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue

1999 • 185 citations

T cell differentiation antigens on lymphocytes in the human intestinal lamina propria.

1992 • 165 citations

Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation

1988 • 163 citations

Influence of theCCR2-V64IPolymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3, CCR5, and CXCR4

1998 • 160 citations

Rapid mucosal CD4+ T-cell depletion and enteropathy in simian immunodeficiency virus–infected rhesus macaques

1999 • 145 citations

CXCR4 utilization is sufficient to trigger CD4+ T cell depletion in HIV-1-infected human lymphoid tissue

1999 • 133 citations

Characterization of Gut-Associated Lymphoid Tissue (GALT) of Normal Rhesus Macaques

1997 • 108 citations

T cell activation and disease severity in HIV infection

1993 • 106 citations

Highly purified CD25⁻resting T cells cannot be infectedde novowith HIV-1

1997 • 79 citations

The function of simian chemokine receptors in the replication of SIV

1998 • 55 citations

Simian immunodeficiency virus is restricted to a subset of blood CD4+ lymphocytes that includes memory cells.

1990 • 53 citations

Expression of CD25 defines peripheral blood mononuclear cells with productive versus latent HIV infection.

1995 • 51 citations

Persistent In Vivo Activation and Transient Anergy to TCR/CD3 Stimulation of Normal Human Intestinal Lymphocytes

1995 • 1 citations

Deleted Work

1955 • 0 citations