Back to search

CD45 isoform phenotypes of human T cells: CD4+CD45RA–RO+ memory T cells re-acquire CD45RA without losing CD45RO

Data up to Jan 2025

Published1999
Citations64
References53

Total Citations Per Year

Abstract

References (53)

Bone marrow transplant

1989 • 3,423 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy

1995 • 1,066 citations

Fas ligand mediates activation-induced cell death in human T lymphocytes.

1995 • 949 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

1997 • 875 citations

T CELL MEMORY

1998 • 863 citations

CD45: An Emerging Role as a Protein Tyrosine Phosphatase Required for Lymphocyte Activation and Development

1994 • 733 citations

Cytotoxic T-cell memory without antigen

1994 • 669 citations

Expression of the Fas ligand in cells of T cell lineage.

1995 • 659 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Expression and modulation of CD44 variant isoforms in humans

1994 • 436 citations

Survival of Mature CD4 T Lymphocytes Is Dependent on Major Histocompatibility Complex Class II–expressing Dendritic Cells

1997 • 402 citations

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1996 • 377 citations

Interconversion of CD45R subsets of CD4 T cells in vivo

1990 • 371 citations

Leukocyte Migration and Adhesion

1995 • 365 citations

T-cell regeneration after bone marrow transplantation: differential CD45 isoform expression on thymic-derived versus thymic-independent progeny

1993 • 293 citations

T cell reconstitution after bone marrow transplantation into adult patients does not resemble T cell development in early life.

1995 • 259 citations

Transforming growth factor-beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype.

1991 • 254 citations

From Naive to Memory T Cells

1996 • 252 citations

T-cell regeneration after bone marrow transplantation: differential CD45 isoform expression on thymic-derived versus thymic-independent progeny

1993 • 250 citations

T-cell regeneration: all repertoires are not created equal

1997 • 246 citations

Reconstitution of the T-Cell Compartment After Bone Marrow Transplantation: Restoration of the Repertoire by Thymic Emigrants

1998 • 223 citations

CD4+ T-cell memory, CD45R subsets and the persistence of antigen—a unifying concept

1998 • 212 citations

Essential Role of the Thymus to Reconstitute Naive (CD45RA+) T-Helper Cells After Human Allogeneic Bone Marrow Transplantation

1997 • 204 citations

T CELL DEPLETION WITH CAMPATH-1 IN ALLOGENEIC BONE MARROW TRANSPLANTATION

1988 • 189 citations

Cyclic regulation of CD45 isoform expression in a long term human CD4+CD45RA+ T cell line.

1991 • 186 citations

Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation.

1989 • 185 citations

Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma.

1991 • 179 citations

CD27: marker and mediator of T-cell activation?

1994 • 169 citations

Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus.

1987 • 159 citations

On the cellular basis of immunological T cell memory

1995 • 159 citations

The CD27 subset of peripheral blood memory CD4+ lymphocytes contains functionally differentiated T lymphocytes that develop by persistent antigenic stimulation in vivo

1992 • 157 citations

The effect of thymic function on immunocompetence following bone marrow transplantation.

1995 • 155 citations

CD45RC Isoforms Define Two Types of CD4 Memory T Cells, One of which Depends on Persisting Antigen

1997 • 125 citations

Immunological memory

1997 • 124 citations

Peripheral T cell survival

1999 • 116 citations

Definition of the thymic generative lineage by selective expression of high molecular weight isoforms of CD45 (T200)

1989 • 108 citations

The organization of mature T-cell pools

1998 • 108 citations

Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T- cell subsets characterized by coexpression of CD45RA and CD45RO isoforms

1996 • 101 citations

Regulation of CD40 ligand expression on naive CD4 T cells: a role for TCR but not co-stimulatory signals

1996 • 83 citations

Rapid PCR analysis of the St14 (DXS52) VNTR

1991 • 82 citations

Identification of the alternatively spliced exons of murine CD45 (T200) required for reactivity with B220 and other T200-restricted antibodies.

1989 • 72 citations

Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations.

1992 • 65 citations

Thymic and extrathymic differentiation and expansion of T lymphocytes following bone marrow transplantation in irradiated recipients.

1997 • 62 citations

Characterization of mixed chimerism in patients with chronic myeloid leukemia transplanted with T-cell-depleted bone marrow: involvement of different hematologic lineages before and after relapse

1993 • 52 citations

Identification of the sequence required for expression of the 2H4 epitope on the human leukocyte common antigens.

1987 • 51 citations

Membrane CD45R isoform exchange on CD4 T cells is rapid, frequent and dynamic in vivo

1994 • 51 citations

THE PHENOTYPE AND RECONSTITUTION OF IMMUNOREGULATORY T CELL SUBSETS AFTER T CELL-DEPLETED ALLOGENEIC AND AUTOLOGOUS BONE MARROW TRANSPLANTATION

1994 • 46 citations

Identical expression of CD45R isoforms by CD45RC+‘revertant’ memory and CD45RC+ naive CD4 T cells

1997 • 46 citations

THE PHENOTYPE AND RECONSTITUTION OF IMMUNOREGULATORY T CELL SUBSETS AFTER T CELL-DEPLETED ALLOGENEIC AND AUTOLOGOUS BONE MARROW TRANSPLANTATION

1994 • 39 citations

Stability of Naive and Memory Phenotypes on Resting CD4 T Cells In Vivo

1999 • 37 citations

HUMAN T LYMPHOCYTE PHENOTYPES AFTER BONE MARROW TRANSPLANTATION T CELLS EXPRESSING IA-LIKE ANTIGEN

1983 • 13 citations

Cited By (0)

No citing papers found in database

CD45 isoform phenotypes of human T cells: CD4+CD45RA–RO+ memory T cells re-acquire CD45RA… (1999) – European Journal of Immunology | Metascience Observatory Explorer