Pharmacological characterization of type 1α metabotropic glutamate receptor‐stimulated [³⁵S]‐GTPγS binding

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

Metabotropic glutamate receptors in brain function and pathology

1993 • 799 citations

Chimeric α ₂ -,β ₂ -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity

1988 • 766 citations

Metabotropic glutamate receptors: Synaptic transmission, modulation, and plasticity

1994 • 713 citations

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

1993 • 695 citations

Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells

1992 • 539 citations

In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding.

1995 • 450 citations

Modulation by mu-opioid agonists of guanosine-5'-O-(3-[35S]thio)triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells.

1995 • 441 citations

Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?

1996 • 437 citations

Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors

1993 • 417 citations

Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes

1994 • 323 citations

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1

1995 • 275 citations

Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

1994 • 197 citations

Transfected muscarinic acetylcholine receptors selectively couple to Gi-type G proteins and Gq/11.

1994 • 171 citations

Muscarinic acetylcholine receptor‐stimulated binding of guanosine 5′‐O‐(3‐thiotriphosphate) to guanine‐nucleotide‐binding proteins in cardiac membranes

1989 • 170 citations

Functional interaction of purified muscarinic receptors with purified inhibitory guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles.

1986 • 161 citations

Pharmacological characterization of acetylcholine‐stimulated [³⁵S]‐GTPγS binding mediated by human muscarinic m1–m4 receptors: antagonist studies

1993 • 156 citations

The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins

1996 • 155 citations

Measurement of guanine nucleotide-binding protein activation by A1 adenosine receptor agonists in bovine brain membranes: stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding.

1993 • 154 citations

Role of the large extracellular domain of metabotropic glutamate receptors in agonist selectivity determination.

1993 • 141 citations

Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity.

1996 • 139 citations

Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family

1994 • 139 citations

Discussion

1996 • 131 citations

Pharmacology characterization of guanine nucleotide exchange reactions in membranes from Cho cells stably transfected with human muscarinic receptors m1–m4

1993 • 121 citations

A Comparison of Two Alternatively Spliced Forms of a Metabotropic Glutamate Receptor Coupled to Phosphoinositide Turnover

1993 • 101 citations

A pharmacological characterization of the mGluR1α subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line

1993 • 96 citations

Signal amplification in HL‐60 granulocytes

1991 • 88 citations

Pharmacological analysis of dopamine stimulation of [³⁵S]‐GTPγS binding via human D_2short and D_2long dopamine receptors expressed in recombinant cells

1996 • 77 citations

Cloning and expression of a human metabotropic glutamate receptor 1 alpha: enhanced coupling on co-transfection with a glutamate transporter.

1995 • 71 citations

<scp>l</scp>‐Glutamate Uptake Inhibitors May Stimulate Phosphoinositide Hydrolysis in Baby Hamster Kidney Cells Expressing mGluR1a via Heteroexchange with <scp>l</scp>‐Glutamate Without Direct Activation of mGluR1a

1994 • 60 citations

Metabotropic glutamate receptors: potential drug targets

1996 • 26 citations

The acidic amino acid transport system of the baby hamster kidney cell line BHK21-C13

1978 • 23 citations

Coupling of muscarinic m1, m2 and m3 acetylcholine receptors, expressed in Chinese hamster ovary cells, to pertussis toxin-sensitive/insensitive guanine nucleotide-binding proteins

1995 • 22 citations

Metabotropic glutamate receptor subtype 1a activates adenylate cyclase when expressed in baby hamster kidney cells

1996 • 18 citations

Competitive Antagonism by Phenylglycine Derivatives at Type 1 Metabotropic Glutamate Receptors

1994 • 15 citations