A pharmacological characterization of the mGluR1α subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

Sequence and expression of a metabotropic glutamate receptor

1991 • 1,200 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Structure-activity relationships in the development of excitatory ammo acid receptor agonists and competitive antagonists

1990 • 905 citations

Guam Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Linked to a Plant Excitant Neurotoxin

1987 • 881 citations

A family of metabotropic glutamate receptors

1992 • 873 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

Glutamate stimulates inositol phosphate formation in striatal neurones

1985 • 734 citations

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

1991 • 638 citations

Signal transduction and pharmacological characteristics of a metabotropic glutamate receptor, mGluRl, in transfected CHO cells

1992 • 539 citations

Cloning, Expression, and Gene Structure of a G Protein-Coupled Glutamate Receptor from Rat Brain

1991 • 524 citations

Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors

1990 • 464 citations

Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters

1990 • 436 citations

Excitatory amino acids and synaptic transmission: the evidence for a physiological function

1990 • 370 citations

Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor

1989 • 318 citations

Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors

1990 • 226 citations

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

1991 • 161 citations

Inhibition of Cyclic AMP Formation by a Selective Metabotropic Glutamate Receptor Agonist

1992 • 158 citations

Activation of a Large‐conductance Ca²⁺‐Dependent K⁺ Channel by Stimulation of Glutamate Phosphoinositide‐coupled Receptors in Cultured Cerebellar Granule Cells

1991 • 139 citations

L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type iv metabotropic glutamate receptor which is negatively coupled to adenylate cyclase

1992 • 135 citations

The non-NMDA receptors: types, protein structure and molecular biology

1990 • 115 citations

The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury

1992 • 102 citations

NMDA and quisqualate reduce a Ca-dependent K+ current by a protein kinase-mediated mechanism

1990 • 100 citations

Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia

1992 • 90 citations

Desensitization of Metabotropic Glutamate Receptors in Neuronal Cultures

1991 • 87 citations

Excitatory Amino Acids Stimulate Inositol Phospholipid Hydrolysis and Reduce Proliferation in Cultured Astrocytes

1990 • 84 citations

Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C

1988 • 77 citations

The labelling of polyphosphoinositides with [32P]Pi and the accumulation of inositol phosphates in vasopressin-stimulated hepatocytes

1986 • 70 citations

Interaction between ß-N-methylamino- l-alanine and excitatory amino acid receptors in brain slices and neuronal cultures

1991 • 65 citations

Activation of polyphosphoinositide metabolism as a signal‐transducing system coupled to excitatory amino acid receptors in astroglial cells

1989 • 63 citations

Pharmacological characterization of the quisqualate receptor coupled to phospholipase C (Qp) in striatal neurons

1991 • 57 citations

Expression of recombinant human plasminogen in mammalian cells is augmented by suppression of plasmin activity

1991 • 51 citations

1S,3R-ACPD-sensitive (metabotropic) [3H]glutamate receptor binding in membranes

1992 • 43 citations

Phorbol Esters Attenuate Glutamate‐Stimulated Inositol Phospholipid Hydrolysis in Neuronal Cultures

1988 • 36 citations

Evidence for Metabotropic Excitatory Amino Acid Receptor Heterogeneity: Developmental and Brain Regional Studies

1992 • 35 citations

Trans-ACPD inhibits cAMP formation via a pertussis toxin-sensitive G-protein

1992 • 30 citations

Na⁺‐dependent high‐affinity uptake of <scp>l</scp>‐glutamate in cultured fibroblasts

1992 • 30 citations

Neurochemical and behavioural effects of muscarinic acetylcholine receptor agonists.

1988 • 7 citations