Apoptosis Induced by Microtubule Disrupting Drugs in Cultured Human Lymphoma Cells

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

Death and the cell

1986 • 616 citations

Apoptosis-the molecular basis of cell death

1992 • 517 citations

Patterns of cell death.

1988 • 470 citations

2,3,7,8-Tetrachlorodibenzo- p -Dioxin Kills Immature Thymocytes by Ca ²⁺ -Mediated Endonuclease Activation

1988 • 460 citations

Definition and incidence of apoptosis : an historical perspective

1991 • 458 citations

Apoptosis: Cell death in tissue regulation

1987 • 393 citations

Cell Death Induced in a Murine Mastocytoma by 42–47°C Heatingin Vitro: Evidence that the Form of Death Changes from Apoptosis to Necrosis Above a Critical Heat Load

1990 • 316 citations

Deletion of cells by apoptosis during castration-induced involution of the rat prostate

1973 • 285 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Cellular signalling in programmed cell death (apoptosis)

1990 • 255 citations

Activation of a suicide process of thymocytes through DNA fragmentation by calcium ionophores and phorbol esters.

1989 • 242 citations

Radiation-induced Interphase Death of Rat Thymocytes is Internally Programmed (Apoptosis)

1988 • 239 citations

Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membranes in T lymphocytes.

1988 • 189 citations

Further studies on the response of intestinal crypt cells of different hierarchical status to eighteen different cytotoxic agents

1987 • 186 citations

DNA fragmentation induced in macrophages by gliotoxin does not require protein synthesis and is preceded by raised inositol triphosphate levels.

1990 • 185 citations

Perspectives on mammalian cell death.

1987 • 183 citations

The Role of Apoptosis in the Response of Cells and Tumours to Mild Hyperthermia

1991 • 176 citations

Apoptosis induced by mild hyperthermia in human and murine tumour cell lines: A study using electron microscopy and DNA gel electrophoresis

1991 • 162 citations

Phorbol esters inhibit apoptosis in IL-2-dependent T lymphocytes

1989 • 95 citations

Cytotoxic thresholds of vincristine in a murine and a human leukemia cell line in vitro.

1979 • 90 citations

Effects of cycloheximide on B-chronic lymphocytic leukaemic and normal lymphocytes in vitro: induction of apoptosis

1991 • 87 citations

DNA Fragmentation in Targets of CTL: An Example of Programmed Cell Death in the Immune System

1985 • 81 citations

Cell death by apoptosis in acute leukaemia

1989 • 69 citations

Heat Shock Protein Synthesis and Cytoskeletal Rearrangements Occur Independently of Intracellular Free Calcium Increases in Drosophila Cells and Tissues

1988 • 42 citations

The frequency and distribution of apoptosis induced by three non-carcinogenic agents in mouse colonic crypts

1984 • 30 citations

Specific loss of microtubules in HL-60 cells leads to programmed cell death (apoptosis)

1990 • 25 citations

Ultrastructural aspects of colchicine ultrasensitivity in CLL lymphocytes.

1981 • 6 citations