Effects of cycloheximide on B-chronic lymphocytic leukaemic and normal lymphocytes in vitro: induction of apoptosis

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

1987 • 923 citations

Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis.

1983 • 616 citations

Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis.

1990 • 489 citations

Patterns of cell death.

1988 • 470 citations

2,3,7,8-Tetrachlorodibenzo- p -Dioxin Kills Immature Thymocytes by Ca ²⁺ -Mediated Endonuclease Activation

1988 • 460 citations

Requirement for RNA and protein synthesis for induced regression of the tadpole tail in organ culture

1966 • 364 citations

C-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment

1984 • 362 citations

An electron‐microscope study of the mode of cell death induced by cancer‐chemotherapeutic agents in populations of proliferating normal and neoplastic cells

1975 • 300 citations

Spontaneous programmed death (apoptosis) of B‐chronic lymphocytic leukaemia cells following their culture in vitro

1989 • 260 citations

Radiation-induced Interphase Death of Rat Thymocytes is Internally Programmed (Apoptosis)

1988 • 239 citations

Apoptosis of vascular endothelial cells by fibroblast growth factor deprivation

1990 • 230 citations

Specific stimulation of actin gene transcription by epidermal growth factor and cycloheximide.

1984 • 215 citations

DNA fragmentation induced in macrophages by gliotoxin does not require protein synthesis and is preceded by raised inositol triphosphate levels.

1990 • 185 citations

Inhibition of palatal epithelial cell death by altered protein synthesis

1976 • 100 citations

A probable role for protein synthesis in intestinal epithelial cell damage induced in vivo by cytosine arabinoside, nitrogen mustard, or X-irradiation.

1970 • 99 citations

DNA Fragmentation in Targets of CTL: An Example of Programmed Cell Death in the Immune System

1985 • 81 citations

Protection of Chinese Hamster Ovary Cells from Hyperthermic Killing by Cycloheximide or Puromycin

1986 • 69 citations

Induction of immunoglobulin gene expression in mouse fibroblasts by cycloheximide treatment.

1984 • 53 citations

Metabolic and ultrastructural aspects of the in vitro lysis of chronic lymphocytic leukemia cells by glucocorticoids.

1982 • 45 citations

Actinomycin D-induced breakage of human KB cell DNA

1974 • 42 citations

T lymphocytes in infectious mononucleosis. II. Response in vitro to interleukin-2 and establishment of T cell lines.

1985 • 35 citations

Analysis of the effects of antibiotics on the structure of nucleosome core particles determined by DNAase I cleavage

1987 • 19 citations

Rapid qualitative changes in mRNA populations in cultured human lymphocytes: comparison of the effects of cycloheximide and concanavalin A

1984 • 15 citations

Fractionation of human lymphocytes using rosette formation with papain-treated mouse erythrocytes

1977 • 12 citations

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