A role for the mitochondrial Na(+)-Ca2+ exchanger in the regulation of oxidative phosphorylation in isolated heart mitochondria.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

[7] Mitochondrial respiratory control and the polarographic measurement of ADP : O ratios

1967 • 1,785 citations

Mechanisms by which mitochondria transport calcium

1990 • 1,630 citations

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

1990 • 1,369 citations

The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex

1979 • 431 citations

The Regulation of Intracellular Calcium

1978 • 415 citations

The Interrelations between the Transport of Sodium and Calcium in Mitochondria of Various Mammalian Tissues

1978 • 402 citations

The Sodium‐Induced Efflux of Calcium from Heart Mitochondria

1976 • 350 citations

Ca2+ As a Second Messenger within Mitochondria of the Heart and other Tissues

1990 • 297 citations

The Calcium‐Induced and Sodium‐Induced Effluxes of Calcium from Heart Mitochondria

1977 • 265 citations

Activities of potassium and sodium ions in rabbit heart muscle.

1975 • 214 citations

Evidence for more than one C²⁺ion transport mechanism in mitochondria

1976 • 211 citations

The Cycling of Calcium, Sodium, and Protons Across the Inner Membrane of Cardiac Mitochondria

1978 • 188 citations

Regulation of Citric Acid Cycle by Calcium

1989 • 187 citations

Effect of diltiazem, a calcium antagonist, on myocardial ischemia

1979 • 157 citations

Role of calcium ions in the regulation of intramitochondrial metabolism. Properties of the Ca2+-sensitive dehydrogenases within intact uncoupled mitochondria from the white and brown adipose tissue of the rat

1980 • 157 citations

Regulation of functional muscarinic receptor expression in tracheal smooth muscle cells

1991 • 154 citations

Role of Ca2+ ions in the regulation of intramitochondrial metabolism in rat heart. Evidence from studies with isolated mitochondria that adrenaline activates the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes by increasing the intramitochondrial concentration of Ca2+

1984 • 151 citations

Selective inhibition of Na+-induced Ca2+ release from heart mitochondria by diltiazem and certain other Ca2+ antagonist drugs.

1982 • 150 citations

Characterization of the effects of Ca2+ on the intramitochondrial Ca2+-sensitive enzymes from rat liver and within intact rat liver mitochondria

1985 • 139 citations

Dehydrogenase activation by Ca2+ in cells and tissues

1991 • 131 citations

Regulation of NAD+-linked isocitrate dehydrogenase and 2-oxoglutarate dehydrogenase by Ca2+ ions within toluene-permeabilized rat heart mitochondria. Interactions with regulation by adenine nucleotides and NADH/NAD+ ratios

1988 • 124 citations

The regulation of the oxidation of fatty acids and other substrates in rat heart mitochondria by changes in the matrix volume induced by osmotic strength, valinomycin and Ca2+

1987 • 121 citations

Effects of diltiazem, a calcium antagonist, on regional myocardial function and mitochondria after brief coronary occlusion

1980 • 119 citations

Mitochondrial Function in the Heart

1979 • 114 citations

Control of mitochondrial ATP synthase in heart cells: inactive to active transitions caused by beating or positive inotropic agents

1990 • 113 citations

The Energy‐State of Mitochondria during the Transport of Ca²⁺

1980 • 110 citations

Intracellular sodium during ischemia and calcium-free perfusion: A Na NMR study

1991 • 104 citations

Studies on mitochondrial Ca2+-transportand matrix Ca2+ using fura-2-loaded rat heart mitochondria

1989 • 103 citations

Cellular mechanisms in congestive heart failure

1988 • 92 citations

Inhibition by malonate of succinic dehydrogenase in heart-muscle preparations

1953 • 90 citations

The calcium-binding ATPase inhibitor protein from bovine heart mitochondria. Purification and properties.

1988 • 71 citations

Evidence for the existence of regulatory sites for Ca2+ on the Na+/Ca2+ carrier of cardiac mitochondria

1982 • 64 citations

Pathways for Ca2+ efflux in heart and liver mitochondria

1987 • 61 citations

Structural dependency of the inhibitory action of benzodiazepines and related compounds on the mitochondrial Na+-Ca2+ exchanger

1988 • 60 citations

Regulation of the mitochondrial Na+Ca2+ antiport by matrix pH

1991 • 52 citations

Mechanism and Physiological Significance of Calcium Transport Across Mammalian Mitochondrial Membranes

1977 • 50 citations

A specific inhibitory action of certain benzothiazepines and benzodiazepines on the sodium-calcium exchange process of heart and brain mitochondria

1983 • 44 citations

Oxidative phosphorylation rate: An index for evaluation of mitochondrial function in myocardial ischaemia

1979 • 38 citations

Electron Probe Analysis of Calcium Content and Movements in Sarcoplasmic Reticulum, Endoplasmic Reticulum, Mitochondria, and Cytoplasm

1986 • 29 citations

Clonazepam and diltiazem both inhibit sodium-calcium exchange of mitochondria, but only diltiazem inhibits the slow action potentials of cardiac muscles

1985 • 27 citations

Involvement of an Na+_Ca2+ exchange system in genesis of ouabain-induced arrhythmias of cultured myocardial cells

1981 • 27 citations

Reversal by uncouplers of oxidative phosphorylation and by Ca2+ of the inhibition of mitochondrial ATPase activity by the ATPase inhibitor protein of rat skeletal muscle.

1981 • 24 citations

Dissociation of Cardiodepression from Cardioprotection with Calcium Antagonists

1989 • 22 citations

Effects of diltiazem upon globally ischemic rat hearts

1987 • 22 citations

Hormonal control of intramitochondrial Ca2+-sensitive enzymes in heart, liver and adipose tissue

1985 • 17 citations

Ouabain-induced tachyarrhythmias and cell damage in isolated perfused guinea-pig hearts: I. Protection by propranolol

1982 • 17 citations

Calcium in the in situ mitochondria of rested and stimulated myocardium

1991 • 17 citations

The Role of Ca²⁺ in the Hormonal Regulation of the Activities of Pyruvate Dehydrogenase and Oxoglutarate Dehydrogenase Complexes^a

1989 • 14 citations

Diltiazem Inhibition of Sodium-Induced Calcium Release

1991 • 14 citations

Electronmicroscopic autoradiographic study of the distribution of 3H-diltiazem in myocardial cells.

1985 • 10 citations