Mammalian Topoisomerase II Activity Is Modulated by the DNA Minor Groove Binder Distamycin in Simian Virus 40 DNA

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

DNA TOPOISOMERASES

1985 • 1,524 citations

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

1984 • 1,477 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

Design of Sequence-Specific DNA-Binding Molecules

1986 • 840 citations

The molecular origin of DNA-drug specificity in netropsin and distamycin.

1985 • 800 citations

Nonintercalating DNA-binding ligands: Specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

1986 • 765 citations

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

1985 • 751 citations

DNA topoisomerase II is required at the time of mitosis in yeast

1985 • 747 citations

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1987 • 691 citations

A bifurcated hydrogen-bonded conformation in the d(A.T) base pairs of the DNA dodecamer d(CGCAAATTTGCG) and its complex with distamycin.

1987 • 671 citations

Hydroxyl radical "footprinting": high-resolution information about DNA-protein contacts and application to lambda repressor and Cro protein.

1986 • 518 citations

Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

1984 • 491 citations

In situ localization of DNA topoisomerase II, a major polypeptide component of the Drosophila nuclear matrix fraction.

1985 • 472 citations

Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage.

1984 • 463 citations

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei.

1981 • 350 citations

Recent studies of DNA topoisomerases

1987 • 323 citations

The metaphase scaffold is helically folded: Sister chromatids have predominantly opposite helical handedness

1988 • 232 citations

Visualization of the bent helix in kinetoplast DNA by electron microscopy

1986 • 226 citations

Purification and characterization of a type II DNA topoisomerase from bovine calf thymus.

1985 • 215 citations

Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II

1986 • 145 citations

Transmission of allosteric effects in DNA

1979 • 137 citations

DNA bending induced by cruciform formation

1985 • 133 citations

Comparison of binding sites in DNA for berenil, netropsin and distamycin

1987 • 128 citations

Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage

1985 • 127 citations

Topological complexes between DNA and topoisomerase II and the effects of polyamines

1989 • 56 citations

Effect of drug-DNA interactions upon transcription initiation at the lac promoter

1987 • 52 citations

Role of DNA intercalation in the inhibition of purified mouse leukemia (L1210) DNA topoisomerase II by 9-aminoacridines

1987 • 50 citations

Specific activation of transcription initiation by the sequence-specific DNA-binding agents distamycin A and netropsin

1987 • 37 citations