Specific activation of transcription initiation by the sequence-specific DNA-binding agents distamycin A and netropsin

Procedure for the rapid, large-scale purification of Escherichia coli DNA-dependent RNA polymerase involving polymin P precipitation and DNA-cellulose chromatography

1975 • 1,157 citations

MECHANISM AND CONTROL OF TRANSCRIPTION INITIATION IN PROKARYOTES

1985 • 1,012 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

The molecular origin of DNA-drug specificity in netropsin and distamycin.

1985 • 800 citations

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1985 • 686 citations

PROTEIN-NUCLEIC ACID INTERACTIONS IN TRANSCRIPTION: A Molecular Analysis

1984 • 620 citations

Genetic Regulation: The Lac Control Region

1975 • 523 citations

Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter

1986 • 336 citations

Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II).

1982 • 332 citations

Repressor structure and the mechanism of positive control

1983 • 324 citations

Rate-limiting steps in RNA chain initiation.

1980 • 308 citations

The interaction of RNA polymerase and lac repressor with the lac control region

1979 • 283 citations

Effects of the Antibiotics Netropsin and Distamycin A on the Structure and Function of Nucleic Acids

1975 • 279 citations

A structural basis for S1 nuclease sensitivity of double-stranded DNA

1985 • 232 citations

A quantitative assay for bacterial RNA polymerases.

1979 • 216 citations

Mechanism of activation of transcription initiation from the λPRM promoter

1982 • 210 citations

Methidiumpropyl-EDTA-Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA

1983 • 175 citations

Structural and Sequence-Dependent Aspects of Drug Intercalation Into Nucleic Acid

1984 • 167 citations

Temperature dependence of the rate constants of the Escherichia coli RNA polymerase-λP promoter interaction

1985 • 162 citations

The Stereochemistry of Actinomycin Binding to DNA and Its Implications in Molecular Biology

1973 • 151 citations

Proton NMR studies on the interaction between distamycin A and a symmetrical DNA dodecamer

1986 • 151 citations

Sequence specificity of actinomycin D and Netropsin binding to pBR322 DNA analyzed by protection from DNase I.

1983 • 116 citations

Poly(dG)-poly(dC) sequences, under torsional stress, induce an altered DNA conformation upon neighboring DNA sequences

1985 • 108 citations

Interaction of netropsin and distamycin with deoxyribonucleic acid: electric dichroism study

1980 • 104 citations

Theoretical studies of the selective binding to DNA of two non-intercalating ligands: netropsin and SN 18071

1983 • 90 citations

The effect of a lambda repressor mutation on the activation of transcription initiation from the lambda PRM promoter

1983 • 83 citations

Promoter recognition by Escherichia coli RNA polymerase. Effects of substitutions in the spacer DNA separating the -10 and -35 regions.

1986 • 75 citations

Production of positively supercoiled DNA by netropsin

1983 • 62 citations

Characterization of the β-lactamase promoter of pBR322

1981 • 49 citations

(dA.dT)-dependent inactivation of the DNA template properties by interaction with netropsin and distamycin A

1975 • 49 citations

500-MHz proton NMR study of poly(dG).cntdot.poly(dC) in solution using one-dimensional nuclear Overhauser effect

1986 • 46 citations

Mutations affecting two different steps in transcription initiation at the phage λ P _RM promoter

1983 • 29 citations

Interaction of catabolite activator protein of Escherichia coli with single-stranded deoxyribonucleic acid

1981 • 13 citations

[Electron microscopy of non-irradiated and irradiated desoxyribonucleic acids].

1961 • 4 citations

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