Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

1984 • 1,477 citations

Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.

1984 • 896 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.

1984 • 559 citations

Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

1980 • 547 citations

Cleavage of DNA by mammalian DNA topoisomerase II.

1983 • 539 citations

Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin

1981 • 382 citations

Double strand DNA cleavage by type II DNA topoisomerase from Drosophila melanogaster.

1983 • 284 citations

Qualitative and quantitative aspects of intercalator-induced DNA strand breaks

1979 • 244 citations

A New Antitumoral Agent: 9-Hydroxyellipticine. Possibility of a Rational Design of Anticancerous Drugs in the Series of DNA Intercalating Drugs

1974 • 229 citations

The interaction of ethidium with synthetic double-stranded polynucleotides at low ionic strength

1978 • 149 citations

Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents

1984 • 139 citations

Protein-associated deoxyribonucleic acid strand breaks produced in mouse leukemia L1210 cells by ellipticine and 2-methyl-9-hydroxyellipticinium

1982 • 90 citations

The formation and resealing of intercalator-induced DNA strand breaks in isolated L1210 cell nuclei

1982 • 73 citations

Ellipticine-induced protein-associated DNA breaks in isolated L1210 nuclei

1982 • 68 citations

Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide

1984 • 46 citations

Absence of swiveling at sites of intercalator-induced protein-associated deoxyribonucleic acid strand breaks in mammalian cell nucleoids

1984 • 41 citations

Evidence that mAMSA induces topoisomerase action

1983 • 25 citations

Reconstitution of intercalator-induced DNA scission by an active component from nuclear extracts

1983 • 23 citations

Absence of a requirement for long-range DNA torsional strain in the production of protein-associated DNA strand breaks in isolated mammalian cell nuclei by the DNA intercalating agent 4′-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA)

1984 • 7 citations