The molecular origin of DNA-drug specificity in netropsin and distamycin.

Structure of a B-DNA dodecamer

1981 • 908 citations

Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG.

1982 • 626 citations

Ordered water structure around a B-DNA dodecamer

1983 • 482 citations

A hypothesis on a specific sequence-dependent conformation of DNA and its relation to the binding of the lac-repressor protein

1979 • 390 citations

Nucleic Acid-Protein Recognition

1977 • 343 citations

Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II).

1982 • 332 citations

DNA-Binding Proteins

1983 • 308 citations

Kinked DNA in crystalline complex with EcoRI endonuclease

1984 • 303 citations

The B̄ to Ā transition of DNA in solution

1974 • 301 citations

Effects of the Antibiotics Netropsin and Distamycin A on the Structure and Function of Nucleic Acids

1975 • 279 citations

Netropsin

1974 • 278 citations

Methidiumpropyl-EDTA-Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA

1983 • 175 citations

Interaction of the oligopeptide antibiotics netropsin and distamycin a with nucleic acids

1971 • 170 citations

Antibiotic-DNA interactions: intermolecular nuclear Overhauser effects in the netropsin-d(C-G-C-G-A-A-T-T-C-G-C-G) complex in solution.

1982 • 139 citations

Structure and motion: Membranes, nucleic acids and proteins

1986 • 137 citations

Netropsin, a DNA-binding oligopeptide structural and binding studies

1979 • 105 citations

Specific interactions of distamycin A and its analogs with (A-T) rich and (G-C) rich duplex regions of DNA and deoxypolynucleotides

1977 • 97 citations

Calorimetric and spectroscoptc Investigation of drug - DNA Interactions. I. The binding of netropsin to poly d(AT)

1983 • 93 citations

Theoretical studies of the selective binding to DNA of two non-intercalating ligands: netropsin and SN 18071

1983 • 90 citations

Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA X Fe(II).

1983 • 76 citations

Distamycin and Penta-N-Methylpyrrolecarboxamide Binding Sites on Native DNA A Comparison of Methidiumproyl-EDTA-Fe(II) Footprinting and DNA Affinity Cleaving

1984 • 74 citations

Influence of nucleotide sequence on dA.dT-specific binding of Netropsin to double stranded DNA

1979 • 63 citations

Binding of Analogues of the Antibiotics Distamycin A and Netropsin to Native DNA

1972 • 61 citations

The Molecular Basis of Cancer

1985 • 54 citations

Z‐DNA and other non‐B‐DNA structures are reversed to B‐DNA by interaction with netropsin

1983 • 50 citations

(dA.dT)-dependent inactivation of the DNA template properties by interaction with netropsin and distamycin A

1975 • 49 citations

Duplex structure formation between oligo(dA)'s and oligo(dT)'s generated by thymine-specific interaction with netropsin

1976 • 35 citations

Chain length-dependent association of distamycin-type oligopeptides with A·T and G·C pairs in polydeoxynucleotide duplexes

1983 • 24 citations