Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II
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Abstract
References (17)
The Biology of Oxygen Radicals
1978 • 3,361 citations
DNA Topoisomerases
1981 • 977 citations
Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
1984 • 896 citations
The Anticancer Agent Adriamycin Can Be Actively Cytotoxic Without Entering Cells
1982 • 578 citations
Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.
1984 • 559 citations
Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break
1980 • 547 citations
Cleavage of DNA by mammalian DNA topoisomerase II.
1983 • 539 citations
Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
1984 • 491 citations
A homogeneous type II DNA topoisomerase from HeLa cell nuclei.
1981 • 361 citations
Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA.
1980 • 314 citations
Double strand DNA cleavage by type II DNA topoisomerase from Drosophila melanogaster.
1983 • 284 citations
Protein-associated DNA breaks in cells treated with adriamycin or ellipticine
1978 • 234 citations
Novel topologically knotted DNA from bacteriophage P4 capsids: studies with DNA topoisomerases
1981 • 231 citations
DNA damage as a basis for 4'-demethylepipodophyllotoxin-9-(4,6-O-ethylidene-beta-D-glucopyranoside) (etoposide) cytotoxicity.
1983 • 223 citations
DNA topoisomerases
1980 • 91 citations
Identification of the breakage-reunion subunit of T4 DNA topoisomerase.
1984 • 88 citations
THE ANTHRACYCLINES
1981 • 1 citations