Drug- and behavior-associated changes in dopamine-related electrochemical signals during intravenous cocaine self-administration in rats

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

Neuroleptics and operant behavior: The anhedonia hypothesis

1982 • 1,021 citations

Responses of monkey dopamine neurons during learning of behavioral reactions

1992 • 986 citations

Self-administration of psychoactive substances by the monkey

1969 • 807 citations

Neuronal activity in monkey ventral striatum related to the expectation of reward

1992 • 755 citations

On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine

1977 • 733 citations

Neuroleptic-Induced "Anhedonia" in Rats: Pimozide Blocks Reward Quality of Food

1978 • 643 citations

Nafion-coated electrodes with high selectivity for CNS electrochemistry

1984 • 632 citations

New concepts in cocaine addiction: The dopamine depletion hypothesis

1985 • 608 citations

Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems

1982 • 560 citations

Increased Lever Pressing for Amphetamine After Pimozide in Rats: Implications for a Dopamine Theory of Reward

1975 • 536 citations

Postcocaine anhedonia. An animal model of cocaine withdrawal.

1991 • 505 citations

Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.

1977 • 490 citations

Studies on the distinction between uptake inhibition and release of [3H]dopamine in rat brain tissue slices

1975 • 473 citations

Sexual behavior enhances central dopamine transmission in the male rat

1990 • 438 citations

Self-injection of amphetamine directly into the brain

1983 • 373 citations

Attenuation of intravenous amphetamine reinforcement by central dopamine blockade in rats

1976 • 371 citations

Extracellular Concentrations of Cocaine and Dopamine Are Enhanced During Chronic Cocaine Administration

1990 • 321 citations

Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration

1992 • 314 citations

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: studies in the ventral tegmental area

1988 • 313 citations

Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording.

1986 • 309 citations

Drugs and Reinforcement Mechanisms: A Critical Review of the Catecholamine Theory

1978 • 293 citations

Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics

1991 • 289 citations

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration.

1989 • 273 citations

Basal extracellular dopamine is decreased in the rat nucleus accumbens during abstinence from chronic cocaine

1991 • 265 citations

Opponent process theory of motivation: Neurobiological evidence from studies of opiate dependence

1989 • 264 citations

Toxicity Associated With Long-term Intravenous Heroin and Cocaine Self-administration in the Rat

1985 • 258 citations

Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.

1989 • 242 citations

Break-points on a progressive ratio schedule reinforced by intravenous cocaine increase following depletion of forebrain serotonin

1990 • 231 citations

Self-administration of psychomotor stimulant drugs: The effects of unlimited access

1976 • 227 citations

Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine

1987 • 226 citations

Depression of Mesolimbic Dopamine Transmission and Sensitization to Morphine During Opiate Abstinence

1992 • 224 citations

Cocaine: An in vivo microdialysis evaluation of its acute action on dopamine transmission in rat striatum

1989 • 218 citations

The use of tetrodotoxin for the characterization of drug-enhanced dopamine release in conscious rats studied by brain dialysis

1987 • 215 citations

CNS stimulants: two distinct mechanisms of action for amphetamine-like drugs

1983 • 203 citations

In vivo monitoring of dopamine release in the rat brain with differential normal pulse voltammetry

1984 • 199 citations

The significance of extracellular calcium for the release of dopamine, acetylcholine and amino acids in conscious rats, evaluated by brain microdialysis

1988 • 186 citations

Dopamine and preparatory behavior: II. A neurochemical analysis.

1989 • 184 citations

Amphetamine-type reinforcement by dopaminergic agonists in the rat

1978 • 182 citations

Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens

1992 • 181 citations

Bromocriptine self-administration and bromocriptine-reinstatement of cocaine-trained and heroin-trained lever pressing in rats

1990 • 179 citations

Relationship between self-administration of amphetamine and monoamine receptors in brain: comparison with cocaine.

1989 • 173 citations

Drug level of d- and l-amphetamine during intravenous self-administration

1974 • 172 citations

Self-administration of optical isomers of amphetamine and methylamphetamine by rats.

1973 • 165 citations

Homeostatic control of ascorbate concentration in CNS extracellular fluid

1982 • 165 citations

Nafion‐coated carbon fiber electrodes for neurochemical studies in brain tissue

1990 • 164 citations

Self-injection of apomorphine in the rat: Positive reinforcement by a dopamine receptor stimulant

1974 • 147 citations

Reinstatement of heroin self-administration habits: morphine prompts and naltrexone discourages renewed responding after extinction

1992 • 141 citations

A psychomotor stimulant theory of addiction.

1987 • 141 citations

Partial dopamine depletion of the prefrontal cortex leads to enhanced mesolimbic dopamine release elicited by repeated exposure to naturally reinforcing stimuli

1992 • 141 citations

Subchronic cocaine treatment enhances cocaine-induced dopamine efflux, studied by in vivo intracerebral dialysis

1989 • 141 citations

Characterization of dopamine release in the substantia nigra by in vivo microdialysis in freely moving rats

1991 • 137 citations

A quantitative investigation of the delay-of-reinforcement gradient.

1943 • 125 citations

Extracellular dopamine in striatum: Influence of nerve impulse activity in medial forebrain bundle and local glutamatergic input

1992 • 123 citations

Increased self-administration of d-amphetamine after destruction of 5-hydroxytryptaminergic neurons

1980 • 122 citations

In vivo monoamine oxidase inhibition by d-amphetamine

1980 • 117 citations

Pharmacological regulation of intravenous cocaine and heroin self-administration in rats: A variable dose paradigm

1989 • 115 citations

6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence intravenous self-administration of cocaine

1986 • 115 citations

Enhanced extracellular dopamine level may be the fundamental neuropharmacological basis of cross-behavioral sensitization between methamphetamine and cocaine — an in vivo dialysis study in freely moving rats

1990 • 114 citations

Drug‐ and behavior‐associated changes in dopamine‐related electrochemical signals during intravenous heroin self‐administration in rats

1993 • 113 citations

In vivo electrochemical studies of monoamine release in the medial prefrontal cortex of the rat

1989 • 111 citations

Substantia nigra dopaminergic unit activity in behaving cats: Effect of arousal on spontaneous discharge and sensory evoked activity

1985 • 109 citations

Extracellular cocaine and dopamine concentrations are linearly related in rat striatum

1988 • 106 citations

Opioid modulation and sensitization of dopamine release elicited by sexually relevant stimuli: a high speed chronoamperometric study in freely behaving rats

1991 • 101 citations

Chronic cocaine alters limbic extracellular dopamine. Neurochemical basis for addiction

1992 • 99 citations

Calcium receptor antagonists modify cocaine effects in the central nervous system differently

1990 • 94 citations

Intravenous Drug Self-Administration: A Special Case of Positive Reinforcement

1987 • 82 citations

Regulation of dopamine and serotonin synthesis by acute administration of cocaine

1990 • 79 citations

The influence of cocaine self-administration on in vivo dopamine and acetylcholine neurotransmission in rat caudate-putamen

1990 • 65 citations

Strategies for studying the neurochemical substrates of drug reinforcement in rodents

1983 • 61 citations

Intracerebral self-administration of amphetamine by rhesus monkeys

1981 • 59 citations

The effects of cholecystokinin (CCK-8) on dopamine-containing nerve terminals in the caudate nucleus and nucleus accumbens of the anesthetized rat: an in vivo electrochemical study

1989 • 58 citations

Evaluation of amphetamine-induced in vivo electrochemical response

1981 • 51 citations

Activity, weight loss, and survival time of food-deprived rats as a function of age.

1961 • 50 citations

Concurrent schedules of cocaine injection in rhesus monkeys: dose variations under independent and non-independent variable-interval procedures.

1975 • 47 citations

Expression of a single dopamine transporter cDNA can confer two cocaine binding sites

1992 • 44 citations

Concurrent intracranial self-stimulation and amphetamine self-administration in rats

1977 • 43 citations

Reinforcement delay of one second severely impairs acquisition of brain self-stimulation

1985 • 43 citations

The enantiomers of the dopamine agonist N-0437: in vivo and in vitro effects on the release of striatal dopamine

1989 • 32 citations

Modulation of terminal excitability of mesolimbic dopaminergic neurons by d-amphetamine and haloperidol

1985 • 23 citations

Striatal Tissue Preparation Facilitates Early Sampling in Microdialysis and Reveals an Index of Neuronal Damage

1993 • 20 citations

Deleted Work

1955 • 0 citations