Increased Lever Pressing for Amphetamine After Pimozide in Rats: Implications for a Dopamine Theory of Reward

Self-administration of psychoactive substances by the monkey

1969 • 807 citations

Possible Etiology of Schizophrenia: Progressive Damage to the Noradrenergic Reward System by 6-Hydroxydopamine

1971 • 480 citations

A biological theory of reinforcement.

1967 • 472 citations

Cocaine-reinforced behavior in rats: effects of reinforcement magnitude and fixed-ratio size.

1968 • 418 citations

Self-administration of d-amphetamine by rats

1968 • 303 citations

A comparison of the capacities of isomers of amphetamine, deoxypipradrol and methylphenidate to inhibit the uptake of tritiated catecholamines into rat cerebral cortex slices, synaptosomal preparations of rat cerebral cortex, hypothalamus and striatum and into adrenergic nerves of rabbit aorta.

1972 • 296 citations

Brainstem pathways of reward.

1969 • 209 citations

Dopaminergic and Noradrenergic Substrates of Positive Reinforcement: Differential Effects of d - and l -Amphetamine

1973 • 197 citations

Psychomotor stimulant self administration as a function of dosage per injection in the Rhesus monkey

1971 • 195 citations

The effects of chlorpromazine on psychomotor stimulant self-administration in the Rhesus monkey

1972 • 186 citations

Drug level of d- and l-amphetamine during intravenous self-administration

1974 • 172 citations

Self-administration of optical isomers of amphetamine and methylamphetamine by rats.

1973 • 165 citations

Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.

1968 • 164 citations

Clinical trials with amphetamine-blocking drugs.

1972 • 147 citations

Evidence of -noradrenergic reward receptors and serotonergic punishment receptors in the rat brain.

1973 • 141 citations

Self-stimulation of noradrenergic cell group (A6) in locus coeruleus of rats.

1973 • 139 citations

Neurochemical mediation of reward: A significant role for dopamine?

1973 • 127 citations

Effects on self-stimulation behavior of drugs influencing dopaminergic neurotransmission mechanisms

1973 • 118 citations

Intracranial Self-Stimulation and Wakefulness: Effect of Manipulating Ambient Brain Catecholamines

1970 • 104 citations

Central catecholamine turnover and self-stimulation behaviour

1971 • 91 citations

Septal stimulation for the initiation of heterosexual behavior in a homosexual male

1972 • 87 citations

Ascending monoamine-containing fiber pathways related to intracranial self-stimulation: Histochemical fluorescence study

1974 • 80 citations

Effect of D-Amphetamine on Rat Brain Noradrenaline and Serotonin

1961 • 70 citations

Function of Catecholamine-containing Neurones in Mammalian Central Nervous System

1972 • 69 citations

Chemical Interactions in Methamphetamine Reinforcement

1968 • 66 citations

Effects of amphetamine on the contents of norepinephrine and its metabolites in the effluent of perfused cerebral ventricles of the cat

1970 • 64 citations

The effects of stimulants and depressants on cocaine self-administration behavior in the Rhesus monkey

1973 • 53 citations

Blocking effect of α-methyltyrosine on amphetamine based reinforcement

1973 • 49 citations

The effect of l-dopa and (+)-amphetamine on the locomotor activity after pimozide and phenoxybenzamine

1972 • 45 citations

Localization of [3H]pimozide in the rat brain in relation to its anti-amphetamine potency

1972 • 38 citations

The effect of alpha- and beta-adrenergic antagonists of the self-stimulation phenomenon

1973 • 15 citations