A mutant T7 RNA polymerase as a DNA polymerase.

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

1985 • 3,185 citations

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.

1993 • 1,097 citations

Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP.

1994 • 694 citations

An attempt to unify the structure of polymerases

1990 • 640 citations

Locations of Anti-AIDS Drug Binding Sites and Resistance Mutations in the Three-dimensional Structure of HIV-1 Reverse Transcriptase

1994 • 512 citations

Crystal Structure of Rat DNA Polymerase β: Evidence for a Common Polymerase Mechanism

1994 • 464 citations

Crystal structure of bacteriophage T7 RNA polymerase at 3.3 Å resolution

1993 • 358 citations

Kinetic mechanism of DNA polymerase I (Klenow)

1987 • 352 citations

Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli.

1990 • 261 citations

Processivity in early stages of transcription by T7 RNA polymerase

1988 • 256 citations

Characterization of T7-specific Ribonucleic Acid Polymerase

1974 • 180 citations

Kinetic analysis of T7 RNA polymerase-promoter interactions with small synthetic promoters

1987 • 134 citations

Rate-limiting steps in the DNA polymerase I reaction pathway

1985 • 133 citations

A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity

1991 • 124 citations

Deoxynucleoside Triphosphate and Pyrophosphate Binding Sites in the Catalytically Competent Ternary Complex for the Polymerase Reaction Catalyzed by DNA Polymerase I (Klenow Fragment)

1995 • 114 citations

An RNA polymerase mutant with reduced accuracy of chain elongation

1986 • 111 citations

Mutations in T7 RNA polymerase that support the proposal for a common polymerase active site structure.

1992 • 103 citations

Interaction of T7 RNA polymerase with DNA in an elongation complex arrested at a specific psoralen adduct site.

1988 • 92 citations

Replication of RNA by the DNA-dependent RNA polymerase of phage T7

1989 • 84 citations

[11] The kinetics and processivity of nucleic acid polymerases

1980 • 72 citations

E. coli DNA polymerase I as a reverse transcriptase.

1993 • 67 citations

Isolation and characterization of mutant bacteriophage T7 RNA polymerases

1992 • 63 citations

T7 RNA polymerase does not interact with the 5'-phosphate of the initiating nucleotide

1989 • 62 citations

Characterization of a set of T7 RNA polymerase active site mutants.

1994 • 59 citations

Interactions of a proteolytically nicked RNA polymerase of bacteriophage T7 with its promoter.

1987 • 42 citations

Bacteriophage T7 RNA Polymerase and Its Active-site Mutants

1994 • 36 citations

Abortive products as initiating nucleotides during transcription by T7 RNA polymerase

1991 • 34 citations

Effect of several metal ions on misincorporation during transcription

1981 • 31 citations

Comparisons of the fidelity of transcription of RNA polymerase I and II following N-hydroxy-2 acetylaminofluorene treatment

1978 • 2 citations