E. coli DNA polymerase I as a reverse transcriptase.

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

1987 • 2,098 citations

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

Identification of four conserved motifs among the RNA-dependent polymerase encoding elements.

1989 • 1,195 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

FIDELITY MECHANISMS IN DNA REPLICATION

1991 • 709 citations

An attempt to unify the structure of polymerases

1990 • 640 citations

Autoradiography using storage phosphor technology

1990 • 531 citations

An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics

1991 • 364 citations

Kinetic mechanism of DNA polymerase I (Klenow)

1987 • 352 citations

Speculations on the early course of evolution.

1986 • 284 citations

Kinetic mechanism whereby DNA polymerase I (Klenow) replicates DNA with high fidelity

1988 • 278 citations

Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli.

1990 • 261 citations

RNA Dependent DNA Polymerase of Human Acute Leukaemic Cells

1970 • 260 citations

Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations

1992 • 186 citations

Elementary steps in the DNA polymerase I reaction pathway

1983 • 179 citations

Distinguishing Reverse Transcriptase of an RNA Tumor Virus from Other Known DNA Polymerases

1971 • 154 citations

Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent.

1990 • 141 citations

The steady state kinetic parameters and non-processivity of Escherichia coli deoxyribonucleic acid polymerase I

1975 • 120 citations

Mutations in T7 RNA polymerase that support the proposal for a common polymerase active site structure.

1992 • 103 citations

Molecular mechanisms of manganese mutagenesis.

1984 • 96 citations

DNA polymerase I and a protein complex bind specifically toE.colipalindromic unit highly repetitive DNA: implications for bacterial chromosome organization

1990 • 85 citations

Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-)

1991 • 81 citations

Copying Natural RNAs with E. coli DNA Polymerase I

1973 • 79 citations

Comparison of some reactions catalyzed by deoxyribonucleic acid polymerase from avian myeloblastosis virus, Escherichia coli, and Micrococcus luteus

1972 • 79 citations

Asp537, Asp812 are essential and Lys631, His811 are catalytically significant in bacteriophage T7 RNA polymerase activity

1992 • 72 citations

Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I.

1975 • 66 citations

Comparative properties of DNA, RNA, and hybrid homopolymer pairs.

1965 • 58 citations

On the early evolution of RNA polymerase

1988 • 55 citations

Structure and function of nucleic acids and proteins

1992 • 41 citations

Mechanisms of error discrimination by Escherichia coli DNA polymerase I

1988 • 32 citations

Action of DNA Polymerase I of Escherichia coli with DNA-RNA Hybrids as Templates

1972 • 31 citations

Replication of Initiated Polyriboadenylic Acid by Mammalian Low Molecular Weight Deoxyribonucleic Acid Polymerase

1974 • 30 citations

On the processive mechanism of Escherichia coli DNA polymerase I. Delayed initiation of polymerization.

1976 • 28 citations

Lys631 residue in the active site of the bacteriophage T7 RNA polymerase

1991 • 27 citations

ISOLATION AND PROPERTIES OF A NUCLEIC ACID HYBRID POLYMERASE

1964 • 22 citations

Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I.

1986 • 22 citations

10-S DNA polymerase from calf thymus which copies both poly(rA) · oligo(dT) and activated DNA

1978 • 19 citations

Further characterization of a poly(rA) · oligo(dT)-dependent activity of multiple DNA polymerase α from calf thymus

1981 • 10 citations