Ion transport ATPases as targets for free radical damage

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

1925 • 19,115 citations

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

[30] Microsomal lipid peroxidation

1978 • 12,818 citations

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts

1986 • 2,052 citations

THE ORGANIZATION OF PROTEINS IN THE HUMAN RED BLOOD CELL MEMBRANE

1974 • 1,554 citations

Calcium Dependence of Toxic Cell Death: A Final Common Pathway

1979 • 1,478 citations

The Reduction of Cytochrome c by Milk Xanthine Oxidase

1968 • 1,201 citations

The importance of free radicals and catalytic metal ions in human diseases

1985 • 939 citations

Lipid peroxidation damage to cell components.

1973 • 925 citations

Transglutaminases

1980 • 818 citations

Calcium pump of the plasma membrane

1991 • 659 citations

Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine

1979 • 637 citations

Central nervous systems trauma and strokeI. Biochemical considerations for oxygen radical formation and lipid peroxidation

1989 • 626 citations

Transglutaminases

1984 • 589 citations

Central nervous system trauma and strokeII. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidation

1989 • 580 citations

The involvement of iron in lipid peroxidation. Importance of ferric to ferrous ratios in initiation.

1986 • 579 citations

Free radicals, lipids and protein degradation

1986 • 556 citations

The requirement for iron (III) in the initiation of lipid peroxidation by iron (II) and hydrogen peroxide.

1987 • 547 citations

Ferritin and superoxide-dependent lipid peroxidation.

1985 • 532 citations

Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation.

1987 • 474 citations

Membrane Transport in Red Cells

1978 • 313 citations

Effects of the 21-aminosteroid U74006F on experimental head injury in mice

1988 • 296 citations

Superoxide‐dependent formation of hydroxyl radicals in the presence of iron salts

1983 • 289 citations

21-Aminosteroid lipid peroxidation inhibitor U74006F protects against cerebral ischemia in gerbils.

1988 • 266 citations

[51] Protein degradation as an index of oxidative stress

1990 • 245 citations

Lipid peroxidation in human red cells.

1989 • 224 citations

Structure and Function of the Calcium Pump Protein of Sarcoplasmic Reticulum

1982 • 196 citations

Effects of the 21-aminosteroid U74006F on posttraumatic spinal cord ischemia in cats

1988 • 176 citations

Mechanisms of cell death

1991 • 174 citations

[73] Determination of nonheme iron, total iron, and copper

1967 • 173 citations

The Calcium Pumping ATPase of the Plasma Membrane

1991 • 169 citations

The calpains

1989 • 161 citations

Extra‐ and Intracellular pH During Near‐Complete Forebrain Ischemia in the Rat

1986 • 149 citations

Reaction of iron-EDTA chelates with the superoxide radical

1982 • 146 citations

Metal ions and oxygen radical reactions in human inflammatory joint disease

1985 • 142 citations

Attenuation of postischemic cerebral hypoperfusion by the 21-aminosteroid U74006F.

1988 • 139 citations

The role of calcium in lethal cell injury

1990 • 128 citations

Pathobiology of heme interaction with the erythrocyte membrane.

1989 • 122 citations

Ferrous ion-EDTA-stimulated phospholipid peroxidation. A reaction changing from alkoxyl-radical- to hydroxyl-radical-dependent initiation

1984 • 113 citations

Inhibition of erythrocyte Ca2+-ATPase by activated oxygen through thiol- and lipid-dependent mechanisms

1986 • 113 citations

Effects of tirilazad mesylate on postischemic brain lipid peroxidation and recovery of extracellular calcium in gerbils.

1991 • 111 citations

Effect of superoxide radical on Ca2+ pumps of coronary artery

1988 • 103 citations

The role of calcium ions in toxic cell injury.

1990 • 94 citations

Inhibition of Ca(2+)-ATPase of vascular smooth muscle sarcoplasmic reticulum by reactive oxygen intermediates

1991 • 78 citations

CALMODULIN AND THE PLASMA MEMBRANE CALCIUM PIIMP*

1980 • 76 citations

Iron in the brain: implications for Parkinson's and Alzheimer's diseases.

1988 • 71 citations

A semi-automated method for the determination of multiple membrane ATPase activities

1980 • 65 citations

Enhancement of (Ca2+ + Mg2+)-ATPase activity of human erythrocyte membranes by hemolysis in isosmotic imidazole buffer. I. General properties of variously prepared membranes and the mechanism of the isosmotic imidazole effect

1977 • 65 citations

Transamidase kinetics. Amide formation in the enzymic reactions of thiol esters with amines

1975 • 48 citations

Further characterization of calpain-mediated proteolysis of the human erythrocyte plasma membrane Ca2+-ATPase

1988 • 44 citations

On the Pathogenetic Mechanism of Hypercalciuria in Genetically Hypertensive Rats of the Milan Strain

1989 • 43 citations

Effects of tirilazad mesylate on postischemic brain lipid peroxidation and recovery of extracellular calcium in gerbils.

1991 • 29 citations

Correlation between Cerebral Blood Flow and ATP Content following Tourniquet-Induced Ischemia in Cat Brain

1984 • 27 citations

Inhibition of membrane erythrocyte (Ca2+ +Mg2+)-ATPase by hemin

1988 • 27 citations

Ascorbate protects against tert-butyl hydroperoxide inhibition of erythrocyte membrane Ca2+ + Mg2+-ATPase

1990 • 26 citations

Inhibition of the erythrocyte (Ca2+ + Mg2+)-ATPase by nonheme iron

1991 • 24 citations

Erythrocyte deficiency in calpain inhibitor activity in essential hypertension.

1988 • 22 citations

The calmodulin-stimulated (Ca2+ + Mg2+)-ATPase in hemoglobin S erythrocyte membranes: effects of sickling and oxidative agents

1987 • 14 citations

RELATIVE ROLES OF SODIUM/CALCIUM EXCHANGE AND ATP‐FUELED CALCIUM TRANSPORT IN THE CONTROL OF CELL CALCIUM*

1982 • 9 citations

Inhibition of the Ca pump ATPase of human red blood cell membranes by dithio compounds.

1988 • 2 citations