[51] Protein degradation as an index of oxidative stress

Free radicals and tissue damage produced by exercise

1982 • 1,754 citations

Protein damage and degradation by oxygen radicals. I. general aspects.

1987 • 1,618 citations

Radioactive Labeling of Proteins in Vitro

1971 • 840 citations

Protein damage and degradation by oxygen radicals. II. Modification of amino acids.

1987 • 840 citations

Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase.

1986 • 608 citations

Protein damage and degradation by oxygen radicals. III. Modification of secondary and tertiary structure.

1987 • 572 citations

Free radicals, lipids and protein degradation

1986 • 556 citations

Purification of two high molecular weight proteases from rabbit reticulocyte lysate.

1987 • 542 citations

Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.

1986 • 525 citations

Protein damage and degradation by oxygen radicals. IV. Degradation of denatured protein.

1987 • 482 citations

Control of Gluconeogenesis from Amino Acids in the Perfused Rat Liver

1969 • 431 citations

Oxygen radicals stimulate intracellular proteolysis and lipid peroxidation by independent mechanisms in erythrocytes.

1987 • 414 citations

Oxidative modification of glutamine synthetase. I. Inactivation is due to loss of one histidine residue.

1983 • 367 citations

Fragmentation of proteins by free radicals and its effect on their susceptibility to enzymic hydrolysis

1986 • 345 citations

Proteins damaged by oxygen radicals are rapidly degraded in extracts of red blood cells.

1987 • 336 citations

Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases.

1985 • 282 citations

Intracellular proteolytic systems may function as secondary antioxidant defenses: An hypothesis

1986 • 279 citations

Oxidative modification of glutamine synthetase. II. Characterization of the ascorbate model system.

1983 • 266 citations

Intracellular Protein Catabolism

1996 • 259 citations

The multicatalytic proteinase of mammalian cells

1989 • 242 citations

Cellular Antioxidant Defense Mechanisms

2019 • 203 citations

Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens

1987 • 196 citations

Macroxyproteinase (M.O.P.): A 670 kDa Proteinase complex that degrades oxidatively denatured proteins in red blood cells

1989 • 182 citations

The myoglobin protein radical. Coupling of Tyr-103 to Tyr-151 in the H2O2-mediated cross-linking of sperm whale myoglobin.

1988 • 180 citations

Superoxide and superoxide dismutase in chemistry, biology and medicine

1987 • 141 citations

Degradation of oxidatively denatured proteins in Escherichia coli

1988 • 126 citations

Mitochondria contain a proteolytic system which can recognize and degrade oxidatively-denatured proteins

1988 • 122 citations

Superoxide dismutase is preferentially degraded by a proteolytic system from red blood cells following oxidative modification by hydrogen peroxide

1988 • 109 citations

Formation of insoluble gels and dityrosine by the action of peroxidase on soluble collagens

1968 • 88 citations

Free-radical-mediated fragmentation of monoamine oxidase in the mitochondrial membrane Roles for lipid radicals

1986 • 88 citations

Oxidatively denaturated proteins are degraded by an ATP-independent proteolytic pathway in escherichia coli

1988 • 87 citations

Lipid peroxidation in biological systems

1989 • 86 citations

Protein degradation is stimulated by ATP in extracts of Escherichia coli.

1979 • 86 citations

Inactivation of Escherichia coli glutamine synthetase by xanthine oxidase, nicotinate hydroxylase, horseradish peroxidase, or glucose oxidase: Effects of ferredoxin, putidaredoxin, and menadione

1985 • 85 citations

Cellular and Molecular Aspects of Aging: The Red Cell as a Model

1986 • 81 citations

Endogenous free radical generation may influence proteolysis in Mitochondria

1985 • 76 citations

Lens proteasome shows enhanced rates of degradation of hydroxyl radical modified alpha-crystallin

1990 • 76 citations

Modulation of the hydrophobicity of glutamine synthetase by mixed‐function oxidation

1988 • 74 citations

Some characteristics of hyperoxia-adapted HeLa cells. A tissue culture model for cellular oxygen tolerance.

1985 • 70 citations

A comparison of the effects of cyanide, hydrogen peroxide, and phenylglyoxal on eucaryotic and procaryotic Cu,Zn superoxide dismutases

1985 • 53 citations

One- and two-electron oxidations of tyrosine, monoiodotyrosine, and diiodotyrosine catalyzed by hog thyroid peroxidase.

1982 • 45 citations

Ubisemiquinone radicals in liver: Implications for a mitochondrial Q cycle in vivo

1982 • 44 citations

Chemical and Biological Alterations Induced by Irradiation of I131 Labeled Human Serum Albumin

1957 • 41 citations

Reaction of bovine‐liver copper‐zinc superoxide dismutase with hydrogen peroxide

1989 • 36 citations

Modulation of myoglobin-H2O2-mediated peroxidation reactions by sulfhydryl compounds.

1988 • 21 citations

The Role of Oxygen Radicals in Cardiovascular Diseases

1988 • 20 citations